Development Level

Tchem 5 | 1,598

IMPC Phenotype

abnormal cecum morphology 1 | 7
abnormal vibrissa morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
decreased cardiac muscle contr... 1 | 11
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged spleen 1 | 41
enlarged uterus 1 | 11
increased circulating choleste... 1 | 66
increased eosinophil cell numb... 1 | 11
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
small superior vagus ganglion 1 | 74

Disease

Carcinoma 5 | 11,493
ovarian cancer 5 | 8,520
cystic fibrosis 4 | 1,696
medulloblastoma, large-cell 4 | 6,241
psoriasis 4 | 6,694
tuberculosis 4 | 2,010
Astrocytoma, Pilocytic 3 | 3,081
Atherosclerosis 3 | 291
Cerebrovascular disease 3 | 238
Colorectal Neoplasms 3 | 243
Coronary artery disease 3 | 268
Liver Cirrhosis, Experimental 3 | 769
Perinatal necrotizing enterocolitis 3 | 21
Pneumonia 3 | 174
Rheumatoid arthritis 3 | 1,191
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
invasive ductal carcinoma 3 | 2,951
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
periodontitis 3 | 293
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Acne 2 | 52
Alcohol abuse 2 | 50
Allergic hypersensitivity disease 2 | 126
Arthritis 2 | 290
Arthritis, Rheumatoid 2 | 174
Aspergillosis 2 | 26
Asthma 2 | 385
Bipolar Disorder 2 | 666
Brain Injuries 2 | 65
Cancer 2 | 2,499
Cholestasis 2 | 155
Chorioamnionitis 2 | 14
Chronic obstructive pulmonary disease 2 | 184
Common cold 2 | 67
Dermatitis 2 | 157
Eosinophilia 2 | 28
Gastritis 2 | 47
Human immunodeficiency virus infectious disease 2 | 138
Hypersensitivity reaction type II disease 2 | 253
Inflammation 2 | 120
Inflammatory bowel disease 2 | 151
Influenza 2 | 142
Keratitis 2 | 62
Kidney disease 2 | 430
Leishmaniasis 2 | 47
Leptospirosis 2 | 18
Liver disease 2 | 237
Malaria 2 | 160
Mastitis 2 | 48
Meningitis 2 | 67
Neoplasm Metastasis 2 | 168
Obesity 2 | 678
Otitis Media 2 | 52
Peritonitis 2 | 43
Reperfusion Injury 2 | 86
Schizophrenia 2 | 1,160
Vasculitis 2 | 80
cutaneous lupus erythematosus 2 | 1,057
group 4 medulloblastoma 2 | 1,855
hepatocellular carcinoma 2 | 547
juvenile dermatomyositis 2 | 1,187
malignant mesothelioma 2 | 3,232
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
Abnormal blistering of the skin 1 | 54
Age related macular degeneration 1 | 72
Animal Mammary Neoplasms 1 | 136
Blister of skin 1 | 54
Brain disease 1 | 96
Carcinoma of colon 1 | 32
Carcinoma, Renal Cell 1 | 124
Fatty Liver 1 | 70
Fatty liver disease 1 | 103
Fibrosis 1 | 44
Filariasis 1 | 21
Hearing Loss 1 | 17
Hepatitis C 1 | 94
Intermittent migraine headaches 1 | 68
Macular degeneration 1 | 65
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Migraine Disorders 1 | 76
Neonatal abstinence syndrome 1 | 11
Neurogenic bowel 1 | 6
Non-alcoholic Fatty Liver Disease 1 | 42
Ovarian Neoplasms 1 | 102
Photodysphoria 1 | 121
Photophobia 1 | 121
Renal Cell Carcinoma 1 | 214
Salmonellosis 1 | 42
Skin bulla 1 | 54
fascioscapulohumeral muscular dystrophy 1 | 100
inflammatory breast cancer 1 | 286
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Non-IDG 4 | 12,091
GPCR 1 | 408

GO Function

lipopolysaccharide receptor ac... 5 | 5
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Lymphocyte antigen 96 LY96 Tchem Non-IDG -2.77678 541.2 369
Platelet-activating factor receptor PTAFR Tchem GPCR -2.02420 116.1 134
Toll-like receptor 4 TLR4 Tchem Non-IDG -3.81927 6905.8 1289
Toll-like receptor 2 TLR2 Tchem Non-IDG -3.50532 3420.9 1102