Development Level

Tbio 16 | 11,445
Tdark 5 | 6,588
Tchem 4 | 1,598
Tclin 2 | 613

IMPC Phenotype

decreased erythrocyte cell num... 2 | 62
increased circulating alkaline... 2 | 122
increased circulating triglyce... 2 | 42
preweaning lethality, complete... 2 | 979
abnormal coat- hair morphology 1 | 19
abnormal retina morphology 1 | 71
abnormal tooth morphology 1 | 24
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased lymphocyte cell numb... 1 | 83
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33

Disease

Carcinoma 17 | 11,493
osteosarcoma 11 | 7,950
psoriasis 11 | 6,694
ovarian cancer 10 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
glioblastoma 9 | 5,792
group 3 medulloblastoma 9 | 4,104
lung cancer 9 | 4,740
medulloblastoma, large-cell 9 | 6,241
Kidney cancer 8 | 2,613
atypical teratoid / rhabdoid tumor 8 | 5,112
diabetes mellitus 8 | 1,728
Atherosclerosis 7 | 291
Autosomal recessive predisposition 7 | 1,442
Breast cancer 7 | 3,578
Coronary artery disease 7 | 268
ependymoma 7 | 4,679
invasive ductal carcinoma 7 | 2,951
lung adenocarcinoma 7 | 2,716
lung carcinoma 7 | 2,843
astrocytic glioma 6 | 2,597
interstitial cystitis 6 | 2,312
malignant mesothelioma 6 | 3,232
oligodendroglioma 6 | 2,850
pancreatic cancer 6 | 2,398
Cardiovascular system disease 5 | 246
Lipid metabolism disorder 5 | 114
Pick disease 5 | 1,894
acute quadriplegic myopathy 5 | 1,158
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
non-small cell lung cancer 5 | 2,890
ulcerative colitis 5 | 1,819
Endometrial cancer 4 | 311
Hypercholesterolemia, Familial 4 | 23
Hyperlipoproteinemia Type II 4 | 12
Obesity 4 | 678
Schizophrenia 4 | 1,160
Seizures 4 | 596
Skin cancer 4 | 469
adrenocortical carcinoma 4 | 1,428
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Age related macular degeneration 3 | 72
Alzheimer's disease 3 | 658
Astrocytoma, Pilocytic 3 | 3,081
Bipolar Disorder 3 | 666
Colorectal Neoplasms 3 | 243
Dementia 3 | 175
Down syndrome 3 | 499
Dyslipidemias 3 | 27
Epilepsy 3 | 792
Liver cancer 3 | 604
Neurodegenerative disease 3 | 414
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
nasopharyngeal carcinoma 3 | 1,058
nephrosclerosis 3 | 333
pediatric high grade glioma 3 | 1,064
progressive supranuclear palsy 3 | 676
Acquired metabolic disease 2 | 336
Amyotrophic lateral sclerosis 2 | 451
Arcus Senilis 2 | 11
Atopic dermatitis 2 | 952
Cancer 2 | 2,499
Cardiovascular Diseases 2 | 59
Cerebrovascular disease 2 | 238
Coarse facial features 2 | 108
Decreased joint mobility 2 | 53
Decreased to absent deep tendon reflexes 2 | 42
Duchenne muscular dystrophy 2 | 601
Electroencephalogram abnormal 2 | 101
Failure to gain weight 2 | 365
Hypercholesterolemia 2 | 44
Hypertension 2 | 396
Kidney disease 2 | 430
Liver Cirrhosis, Experimental 2 | 769
Liver disease 2 | 237
Melanoma 2 | 711
Movement Disorders 2 | 55
Multiple Sclerosis 2 | 540
Muscle Spasticity 2 | 195
Myocardial Infarction 2 | 151
Parkinson's disease 2 | 392
Pediatric failure to thrive 2 | 365
Recurrent respiratory infections 2 | 141
Thickened facial skin with coarse facial features 2 | 108
Toxic encephalopathy 2 | 141
active Crohn's disease 2 | 922
cutaneous lupus erythematosus 2 | 1,057
esophageal adenocarcinoma 2 | 737
gastric cancer 2 | 459
hearing impairment 2 | 199
hepatocellular carcinoma 2 | 547
juvenile dermatomyositis 2 | 1,187
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Blood and immune system 27 | 16,909
Endocrine System 27 | 18,159
Digestive Tract 26 | 17,369
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678
Nervous System 24 | 16,725
Respiratory system 23 | 16,393
Cardiovascular System 21 | 15,192

Target Family

Non-IDG 21 | 12,091
Transporter 4 | 473
Ion Channel 1 | 344
Kinase 1 | 634

GO Function

lipid transporter activity 27 | 27
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HEAT repeat-containing protein 4 HEATR4 Tdark Non-IDG 0.90 0.10 40
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
ATP-binding cassette sub-family A member 5 ABCA5 Tbio Transporter -1.09683 13.2 131
ATP-binding cassette sub-family A member 3 ABCA3 Tbio Transporter -2.25972 187.7 32
ATP-binding cassette sub-family A member 12 ABCA12 Tbio Transporter -2.05873 115.5 66
Maestro heat-like repeat-containing protein family member 6 MROH6 Tdark Non-IDG 0.78 0.05 6
Integrator complex subunit 7 INTS7 Tdark Non-IDG -0.82823 6.83 37
Brefeldin A-inhibited guanine nucleotide-exchange protein 3 ARFGEF3 Tdark Non-IDG -0.47852 3.29 6
Pulmonary surfactant-associated protein A1 SFTPA1 Tbio Non-IDG -2.05283 109.3 228
HEAT repeat-containing protein 6 HEATR6 Tdark Non-IDG -1.49589 12.0 43