Development Level

Tbio 7 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged seminal vesicle 1 | 10
enlarged testis 1 | 6
preweaning lethality, complete... 1 | 979

Disease

psoriasis 8 | 6,694
Carcinoma 6 | 11,493
atypical teratoid / rhabdoid tumor 5 | 5,112
group 4 medulloblastoma 5 | 1,855
medulloblastoma, large-cell 5 | 6,241
ovarian cancer 5 | 8,520
ependymoma 4 | 4,679
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
osteosarcoma 3 | 7,950
pancreatic cancer 3 | 2,398
posterior fossa group B ependymoma 3 | 416
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Breast cancer 2 | 3,578
Dental caries 2 | 164
Down syndrome 2 | 499
Pick disease 2 | 1,894
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
lung cancer 2 | 4,740
nephrosclerosis 2 | 333
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Acute kidney injury 1 | 70
Adverse reaction to drug 1 | 61
Allergic asthma 1 | 6
Asthma management 1 | 19
Carcinoma of thyroid 1 | 17
Cardiovascular system disease 1 | 246
Cataract 1 | 297
Cerebrovascular disease 1 | 238
Congenital muscular dystrophy 1 | 29
Coronary artery disease 1 | 268
Disease Progression 1 | 136
Drug-Related Side Effects and Adverse Reactions 1 | 62
Gastrointestinal stromal tumor 1 | 62
Globe disease 1 | 67
Heart failure 1 | 162
Hypercholesterolemia, Familial 1 | 23
Hyperlipoproteinemia Type IIa 1 | 11
Hypomyelinating leukodystrophy 1 | 9
Intellectual disability 1 | 1,016
Kidney cancer 1 | 2,613
Liver Cirrhosis, Experimental 1 | 769
Liver cell carcinoma 1 | 15
MUSCULAR DYSTROPHY, CONGENITAL, WITH CATARACTS AND INTELLECTUAL DISABILITY 1 | 1
Mastitis 1 | 48
Metastasis from malignant tumor of colon 1 | 8
Metastatic Breast Cancer Progression Post-Antiestrogen Therapy 1 | 4
Myocardial Reperfusion Injury 1 | 37
Non-allergic asthma 1 | 5
Oculocerebrorenal syndrome 1 | 29
Parkinson's disease 1 | 392
Pseudohypoparathyroidism 1 | 18
Renal Cell Carcinoma 1 | 214
Secondary progressive multiple sclerosis 1 | 10
Seizures 1 | 596
Staphyloenterotoxemia 1 | 18
Stomach Neoplasms 1 | 300
Toxic shock syndrome 1 | 28
Ventricular Dysfunction, Left 1 | 22
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
acute quadriplegic myopathy 1 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
dermatomyositis 1 | 966
esophageal adenocarcinoma 1 | 737
gastric cancer 1 | 459
hepatocellular carcinoma 1 | 547
inflammatory breast cancer 1 | 286
interstitial lung disease 1 | 298
lung carcinoma 1 | 2,843
mucosa-associated lymphoid tissue lymphoma 1 | 484
non primary Sjogren syndrome sicca 1 | 891
pancreatic carcinoma 1 | 562
pediatric high grade glioma 1 | 1,064
permanent atrial fibrillation 1 | 45
pituitary cancer 1 | 1,972
primitive neuroectodermal tumor 1 | 3,035
sarcoidosis 1 | 370
ulcerative colitis 1 | 1,819

Tissue

Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Blood and immune system 9 | 16,909
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192
Skin and soft tissues 8 | 17,230

Target Family

Enzyme 11 | 4,145

GO Function

lipid phosphatase activity 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phospholipid phosphatase 2 PLPP2 Tbio Enzyme -1.34465 21.0 105
Phospholipid phosphatase 6 PLPP6 Tbio Enzyme -1.30463 23.2 111
Phospholipid phosphatase 3 PLPP3 Tbio Enzyme -1.77858 65.1 94
Phospholipid phosphatase-related protein type 4 PLPPR4 Tbio Enzyme -1.15591 13.7 92
Phospholipid phosphatase-related protein type 5 PLPPR5 Tdark Enzyme -0.07918 1.14 87
Bifunctional epoxide hydrolase 2 EPHX2 Tchem Enzyme -2.57266 349.1 245
Phospholipid phosphatase-related protein type 3 PLPPR3 Tbio Enzyme -1.11680 11.9 86
Inositol polyphosphate 5-phosphatase K INPP5K Tbio Enzyme -0.93536 10.1 92
Phospholipid phosphatase-related protein type 2 PLPPR2 Tdark Enzyme 0.30 0.58 56
Phospholipid phosphatase 1 PLPP1 Tbio Enzyme -1.44460 28.0 119