Development Level

Tbio 2 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

Disease

lung cancer 5 | 4,740
ovarian cancer 5 | 8,520
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
medulloblastoma, large-cell 4 | 6,241
Carcinoma 3 | 11,493
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
osteosarcoma 3 | 7,950
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
Autosomal recessive predisposition 2 | 1,442
Cardiovascular system disease 2 | 246
Cholesterol ester storage disease 2 | 6
Multiple myeloma 2 | 1,332
Obesity 2 | 678
Steatorrhea 2 | 34
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
primary Sjogren syndrome 2 | 735
subependymal giant cell astrocytoma 2 | 2,287
Abdomen distended 1 | 43
Amnestic disorder 1 | 35
Anemia 1 | 365
Anemia, Megaloblastic 1 | 16
Arteriosclerosis 1 | 11
Ascites 1 | 22
Astrocytoma, Pilocytic 1 | 3,081
Breast cancer 1 | 3,578
Cachexia 1 | 50
Cancer 1 | 2,499
Chorioamnionitis 1 | 14
Chronic diarrhea 1 | 29
Coronary artery disease 1 | 268
Death in early childhood 1 | 82
Death in infancy 1 | 82
Diarrhea 1 | 253
Down syndrome 1 | 499
Duchenne muscular dystrophy 1 | 601
Ectropion 1 | 38
Esophageal Varices 1 | 6
Exocrine pancreatic insufficiency 1 | 32
Failure to gain weight 1 | 365
Fibrosis, Liver 1 | 32
Gilles de la Tourette syndrome 1 | 47
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Hardened artery wall 1 | 6
Hemoglobin low 1 | 124
Hepatomegaly 1 | 285
Hepatosplenomegaly 1 | 22
Hypercholesterolemia 1 | 44
Hypertriglyceridemia result 1 | 37
Idiopathic pulmonary arterial hypertension 1 | 40
Intestinal disease 1 | 14
Lipid metabolism disorder 1 | 114
Liver Cirrhosis, Experimental 1 | 769
Liver Failure 1 | 73
Major Depressive Disorder 1 | 301
Malnutrition 1 | 11
Methemoglobinemia 1 | 17
Nausea and vomiting 1 | 97
Neutral lipid storage disease 1 | 12
Niemann-Pick disease, type C 1 | 5
Pancreatic Insufficiency 1 | 13
Pancreatitis 1 | 123
Panniculitis 1 | 9
Pediatric failure to thrive 1 | 365
Pick disease 1 | 1,894
Poor growth 1 | 114
Prostate cancer 1 | 175
Prostatic Neoplasms 1 | 495
Protuberant abdomen 1 | 16
Pulmonary hypertension 1 | 85
Serum cholesterol raised 1 | 22
Very poor growth 1 | 114
Vomiting 1 | 116
Waldenstrons macroglobulinemia 1 | 765
Wolman disease 1 | 6
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
cystic fibrosis 1 | 1,696
hereditary spastic paraplegia 1 | 318
juvenile dermatomyositis 1 | 1,187
lung carcinoma 1 | 2,843
pancreatic cancer 1 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
periodontitis 1 | 293
pituitary cancer 1 | 1,972
pulmonary arterial hypertension 1 | 75
tuberculosis 1 | 2,010

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Enzyme 6 | 4,145

GO Function

lipase activity 6 | 6
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein ABHD1 ABHD1 Tdark Enzyme -0.22185 2.20 106
Lysosomal acid lipase/cholesteryl ester hydrolase LIPA Tchem Enzyme -2.80202 616.3 170
Lipid droplet-associated hydrolase LDAH Tbio Enzyme -0.86454 7.55 76
Acyl-protein thioesterase 1 LYPLA1 Tchem Enzyme -1.83454 68.8 214
Arylacetamide deacetylase AADAC Tbio Enzyme -1.33418 25.6 116
Pancreatic triacylglycerol lipase PNLIP Tclin Enzyme -3.31721 2006.8 311