Development Level

Tbio 15 | 11,445
Tchem 5 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

impaired glucose tolerance 2 | 75
increased startle reflex 2 | 112
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal tooth morphology 1 | 24
decreased circulating choleste... 1 | 93
decreased circulating creatine... 1 | 4
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating creatine... 1 | 5
increased circulating glycerol... 1 | 9
increased circulating triglyce... 1 | 42
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 19 | 11,493
glioblastoma 14 | 5,792
ovarian cancer 14 | 8,520
osteosarcoma 13 | 7,950
medulloblastoma, large-cell 11 | 6,241
Cancer 10 | 2,499
lung cancer 10 | 4,740
psoriasis 10 | 6,694
malignant mesothelioma 9 | 3,232
Kidney cancer 8 | 2,613
atypical teratoid / rhabdoid tumor 8 | 5,112
astrocytic glioma 7 | 2,597
group 3 medulloblastoma 7 | 4,104
ependymoma 6 | 4,679
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,035
Multiple myeloma 5 | 1,332
Prostatic Neoplasms 5 | 495
astrocytoma 5 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Breast Neoplasms 4 | 445
Carcinoma, Hepatocellular 4 | 228
Endometriosis 4 | 540
Liver carcinoma 4 | 240
Mammary Neoplasms 4 | 425
Pick disease 4 | 1,894
aldosterone-producing adenoma 4 | 665
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
oligodendroglioma 4 | 2,850
subependymal giant cell astrocytoma 4 | 2,287
Bladder Neoplasm 3 | 112
Breast cancer 3 | 3,578
Liver cancer 3 | 604
Primary cutaneous T-cell lymphoma 3 | 29
Urinary Bladder Neoplasms 3 | 114
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
adult high grade glioma 3 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
ulcerative colitis 3 | 1,819
AMYOTROPHIC LATERAL SCLEROSIS 1 2 | 49
Abnormality of cardiovascular system morphology 2 | 23
Acquired scoliosis 2 | 281
Adenocarcinoma 2 | 122
Adenoid Cystic Carcinoma 2 | 99
Amyotrophic lateral sclerosis 2 | 451
Bipolar Disorder 2 | 666
Broad flat nasal bridge 2 | 236
Carcinoma, Adenoid Cystic 2 | 99
Carcinoma, Transitional Cell 2 | 32
Cerebellar hypoplasia and atrophy 2 | 41
Chemical and Drug Induced Liver Injury 2 | 195
Chronic Lymphocytic Leukemia 2 | 262
Coarse facial features 2 | 108
Coffin-Siris syndrome 2 | 17
Concave bridge of nose 2 | 195
Congenital deafness 2 | 185
Curvature of spine 2 | 282
Deafness 2 | 198
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Epilepsy 2 | 792
Fatty liver disease 2 | 103
Generalized hirsutism 2 | 36
Hearing Loss, Partial 2 | 185
Joint hyperflexibility 2 | 78
Liver Cirrhosis, Experimental 2 | 769
Liver neoplasms 2 | 130
Long eyelashes 2 | 37
Lymphoid leukemia 2 | 160
Nasal bridge wide 2 | 236
Neoplasm Metastasis 2 | 168
Patella aplasia-hypoplasia 2 | 12
Peripheral T-cell lymphoma 2 | 25
Recurrent respiratory infections 2 | 141
Seizures 2 | 596
Strabismus 2 | 270
Thickened facial skin with coarse facial features 2 | 108
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
dermatomyositis 2 | 966
hearing impairment 2 | 199
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
nephrosclerosis 2 | 333
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
spina bifida 2 | 1,074
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 22 | 16,909
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Nervous System 21 | 16,725
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 8 | 12,091
Transcription Factor 7 | 1,400
Epigenetic 3 | 242
Nuclear Receptor 2 | 48
Enzyme 1 | 4,145
TF/Epigenetic 1 | 38
Transporter 1 | 473

GO Function

ligand-dependent nuclear recep... 23 | 23
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Tchem TF/Epigenetic -2.07564 115.2 51
Zinc transporter 9 SLC30A9 Tbio Transporter -0.88627 10.1 105
Transcription intermediary factor 1-alpha TRIM24 Tchem Epigenetic -2.15509 143.0 372
Insulin gene enhancer protein ISL-1 ISL1 Tbio Transcription Factor -2.63352 410.3 382
Prospero homeobox protein 1 PROX1 Tbio Transcription Factor -2.31691 210.1 472
AT-rich interactive domain-containing protein 1A ARID1A Tbio Transcription Factor -2.61778 423.3 132
Putative nuclear receptor corepressor 1-like protein NCOR1P1 NCOR1P1 Tdark Non-IDG 0.00000 0
Transcription factor jun-D JUND Tbio Transcription Factor -2.47292 252.6 452
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 SMARCD3 Tbio Non-IDG -1.30404 22.1 170
Nuclear receptor corepressor 2 NCOR2 Tchem Transcription Factor -2.83392 645.1 189