Development Level

Tbio 15 | 11,445
Tchem 5 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

impaired glucose tolerance 2 | 75
increased startle reflex 2 | 112
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal tooth morphology 1 | 24
decreased circulating choleste... 1 | 93
decreased circulating creatine... 1 | 4
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating creatine... 1 | 5
increased circulating glycerol... 1 | 9
increased circulating triglyce... 1 | 42
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 19 | 11,493
glioblastoma 14 | 5,792
ovarian cancer 14 | 8,520
osteosarcoma 13 | 7,950
medulloblastoma, large-cell 11 | 6,241
Cancer 10 | 2,499
lung cancer 10 | 4,740
psoriasis 10 | 6,694
malignant mesothelioma 9 | 3,232
Kidney cancer 8 | 2,613
atypical teratoid / rhabdoid tumor 8 | 5,112
astrocytic glioma 7 | 2,597
group 3 medulloblastoma 7 | 4,104
ependymoma 6 | 4,679
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,035
Multiple myeloma 5 | 1,332
Prostatic Neoplasms 5 | 495
astrocytoma 5 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Breast Neoplasms 4 | 445
Carcinoma, Hepatocellular 4 | 228
Endometriosis 4 | 540
Liver carcinoma 4 | 240
Mammary Neoplasms 4 | 425
Pick disease 4 | 1,894
aldosterone-producing adenoma 4 | 665
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
oligodendroglioma 4 | 2,850
subependymal giant cell astrocytoma 4 | 2,287
Bladder Neoplasm 3 | 112
Breast cancer 3 | 3,578
Liver cancer 3 | 604
Primary cutaneous T-cell lymphoma 3 | 29
Urinary Bladder Neoplasms 3 | 114
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
adult high grade glioma 3 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
ulcerative colitis 3 | 1,819
AMYOTROPHIC LATERAL SCLEROSIS 1 2 | 49
Abnormality of cardiovascular system morphology 2 | 23
Acquired scoliosis 2 | 281
Adenocarcinoma 2 | 122
Adenoid Cystic Carcinoma 2 | 99
Amyotrophic lateral sclerosis 2 | 451
Bipolar Disorder 2 | 666
Broad flat nasal bridge 2 | 236
Carcinoma, Adenoid Cystic 2 | 99
Carcinoma, Transitional Cell 2 | 32
Cerebellar hypoplasia and atrophy 2 | 41
Chemical and Drug Induced Liver Injury 2 | 195
Chronic Lymphocytic Leukemia 2 | 262
Coarse facial features 2 | 108
Coffin-Siris syndrome 2 | 17
Concave bridge of nose 2 | 195
Congenital deafness 2 | 185
Curvature of spine 2 | 282
Deafness 2 | 198
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Epilepsy 2 | 792
Fatty liver disease 2 | 103
Generalized hirsutism 2 | 36
Hearing Loss, Partial 2 | 185
Joint hyperflexibility 2 | 78
Liver Cirrhosis, Experimental 2 | 769
Liver neoplasms 2 | 130
Long eyelashes 2 | 37
Lymphoid leukemia 2 | 160
Nasal bridge wide 2 | 236
Neoplasm Metastasis 2 | 168
Patella aplasia-hypoplasia 2 | 12
Peripheral T-cell lymphoma 2 | 25
Recurrent respiratory infections 2 | 141
Seizures 2 | 596
Strabismus 2 | 270
Thickened facial skin with coarse facial features 2 | 108
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
dermatomyositis 2 | 966
hearing impairment 2 | 199
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
nephrosclerosis 2 | 333
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
spina bifida 2 | 1,074
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 22 | 16,909
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Nervous System 21 | 16,725
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 8 | 12,091
Transcription Factor 7 | 1,400
Epigenetic 3 | 242
Nuclear Receptor 2 | 48
Enzyme 1 | 4,145
TF/Epigenetic 1 | 38
Transporter 1 | 473

GO Function

ligand-dependent nuclear recep... 23 | 23
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc transporter 9 SLC30A9 Tbio Transporter -0.88627 10.1 105
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Tchem TF/Epigenetic -2.07564 115.2 51
Transcription intermediary factor 1-alpha TRIM24 Tchem Epigenetic -2.15509 143.0 372
Insulin gene enhancer protein ISL-1 ISL1 Tbio Transcription Factor -2.63352 410.3 382
Putative nuclear receptor corepressor 1-like protein NCOR1P1 NCOR1P1 Tdark Non-IDG 0.00000 0
AT-rich interactive domain-containing protein 1A ARID1A Tbio Transcription Factor -2.61778 423.3 132
Prospero homeobox protein 1 PROX1 Tbio Transcription Factor -2.31691 210.1 472
Transcription factor jun-D JUND Tbio Transcription Factor -2.47292 252.6 452
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 SMARCD3 Tbio Non-IDG -1.30404 22.1 170
Activating signal cointegrator 1 TRIP4 Tbio Non-IDG -0.69308 4.86 198