Development Level

Tbio 13 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

female infertility 1 | 60
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 12 | 11,493
lung cancer 10 | 4,740
osteosarcoma 10 | 7,950
ovarian cancer 10 | 8,520
Breast cancer 8 | 3,578
medulloblastoma, large-cell 8 | 6,241
ependymoma 6 | 4,679
group 3 medulloblastoma 6 | 4,104
psoriasis 6 | 6,694
atypical teratoid / rhabdoid tumor 5 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
malignant mesothelioma 5 | 3,232
primitive neuroectodermal tumor 5 | 3,035
Atopic dermatitis 4 | 952
Emery-Dreifuss muscular dystrophy 4 | 23
Waldenstrons macroglobulinemia 4 | 765
adult high grade glioma 4 | 3,801
glioblastoma 4 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
oligodendroglioma 4 | 2,850
subependymal giant cell astrocytoma 4 | 2,287
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Progeria 3 | 25
Rheumatoid arthritis 3 | 1,191
colon cancer 3 | 1,478
dermatomyositis 3 | 966
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
primary Sjogren syndrome 3 | 735
Acrodermatitis enteropathica 2 | 18
Amyloidosis 2 | 67
Bipolar Disorder 2 | 666
Cardiomyopathy 2 | 116
Dilated cardiomyopathy 2 | 56
Duchenne muscular dystrophy 2 | 601
Familial isolated dilated cardiomyopathy 2 | 41
Kidney cancer 2 | 2,613
Liver cancer 2 | 604
Melanoma 2 | 711
Multiple myeloma 2 | 1,332
Muscular dystrophy 2 | 75
Myasthenia gravis 2 | 23
Nezelof syndrome 2 | 4
Oligospermia 2 | 36
Pick disease 2 | 1,894
Pruritus 2 | 58
Skin Ulcer 2 | 48
Skin cancer 2 | 469
active Crohn's disease 2 | 922
acute quadriplegic myopathy 2 | 1,158
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
dilated cardiomyopathy 1T 2 | 2
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
interstitial cystitis 2 | 2,312
nasopharyngeal carcinoma 2 | 1,058
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abnormal maturation of the pelvis bone 1 | 3
Abnormal ossification involving the femoral head and neck 1 | 2
Abnormal pelvis bone ossification 1 | 3
Absent or minimally ossified vertebral bodies 1 | 3
Absent toenails (anonychia) 1 | 7
Blepharitis 1 | 23
CREST Syndrome 1 | 16
Calvarial defect 1 | 10
Cellulitis of eyelid 1 | 17
Chronic diarrhea 1 | 29
Cranial defect 1 | 10
Dry Eye Syndromes 1 | 8
Eyebrow abnormalities 1 | 12
Fissured tongue 1 | 25
Gastrointestinal Hemorrhage 1 | 52
Islets of Langerhans hyperplasia 1 | 11
Lethal skeletal dysplasia 1 | 6
Mesomelia 1 | 8
Mucosal telangiectasiae 1 | 14
Myalgia 1 | 54
Pelger-Huet anomaly 1 | 8
Pleural effusion disorder 1 | 6
Schizotypal personality disorder 1 | 7
Sclerodactyly 1 | 1
Scleroderma 1 | 7
Scleroderma-like secondary cutaneous sclerosis 1 | 7
Seizures, Focal 1 | 14
Short phalanx of finger 1 | 32
Skull defect 1 | 10
Spade-like hand 1 | 16
White blood cell abnormality 1 | 1
Xerophthalmia 1 | 16
Xerostomia 1 | 42
joint abnormality 1 | 5

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Non-IDG 12 | 12,091
Enzyme 3 | 4,145
Epigenetic 1 | 242

GO Function

lamin binding 16 | 16
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interferon alpha-inducible protein 27, mitochondrial IFI27 Tbio Non-IDG -1.51419 33.3 0
Nuclear prelamin A recognition factor NARF Tbio Non-IDG -1.27665 18.1 132
A-kinase anchor protein 8-like AKAP8L Tbio Enzyme -1.03730 13.2 140
Plakophilin-1 PKP1 Tbio Non-IDG -1.86062 76.3 103
Transmembrane protein 201 TMEM201 Tdark Non-IDG -2.07296 119.8 17
Nesprin-1 SYNE1 Tbio Non-IDG -2.28105 171.4 65
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like BNIP3L Tbio Non-IDG -2.20837 153.7 355
Major prion protein PRNP Tchem Non-IDG -3.45326 5611.1 484
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 PLCB1 Tbio Enzyme -2.50444 332.8 190
Lamina-associated polypeptide 2, isoform alpha TMPO Tbio Non-IDG -2.11834 246.0 283