Development Level

Tclin 5 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

Disease

Bipolar Disorder 5 | 666
Carcinoma 5 | 11,493
Epilepsy characterized by intractable complex partial seizures 5 | 28
Kidney cancer 5 | 2,613
Lennox-Gastaut syndrome 5 | 34
Migraine Prevention 5 | 23
Schizophrenia 5 | 1,160
Simple partial seizure 5 | 26
Tonic-clonic epilepsy 5 | 47
astrocytic glioma 4 | 2,597
Epilepsy 3 | 792
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
psoriasis 3 | 6,694
Alcoholic Intoxication, Chronic 2 | 289
Attention deficit hyperactivity disorder 2 | 278
Autistic Disorder 2 | 364
Liver cancer 2 | 604
Melanoma 2 | 711
Psychotic Disorders 2 | 151
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
subependymal giant cell astrocytoma 2 | 2,287
Acquired metabolic disease 1 | 336
Alcohol dependence 1 | 107
Alcoholic Intoxication 1 | 34
Astrocytoma, Pilocytic 1 | 3,081
Autosomal recessive non-syndromic intellectual disability 1 | 7
Autosomal recessive predisposition 1 | 1,442
Bipolar I disorder 1 | 23
Brain Ischemia 1 | 110
Cognitive delay 1 | 608
Depression, Bipolar 1 | 12
Depressive disorder 1 | 409
Dull intelligence 1 | 645
Global developmental delay 1 | 608
Huntington's disease 1 | 76
Infantile onset 1 | 238
Intellectual disability 1 | 1,016
Kidney disease 1 | 430
Low intelligence 1 | 645
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 6 1 | 1
Major Depressive Disorder 1 | 301
Mental Depression 1 | 333
Mental Retardation 1 | 645
Mental and motor retardation 1 | 608
Mental deficiency 1 | 645
Migraine 1 | 83
Mood Disorders 1 | 184
Nonorganic psychosis 1 | 84
Organ system cancer 1 | 18
Overdose of cocaine 1 | 1
Poor school performance 1 | 645
Psychosexual Disorders 1 | 6
Retinitis pigmentosa 13 1 | 11
Seizures 1 | 596
Sexual Dysfunctions, Psychological 1 | 6
Skin cancer 1 | 469
Small Cell Lung Carcinoma 1 | 41
Small cell carcinoma of lung 1 | 45
Spinocerebellar ataxia type 11 1 | 4
Substance-Related Disorders 1 | 115
Unipolar Depression 1 | 250
adult high grade glioma 1 | 3,801
atypical teratoid/rhabdoid tumor 1 | 357
cocaine use 1 | 11
group 4 medulloblastoma 1 | 1,855
heavy drinking 1 | 5
lung cancer 1 | 4,740
malignant mesothelioma 1 | 3,232
non primary Sjogren syndrome sicca 1 | 891
ovarian cancer 1 | 8,520
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
primitive neuroectodermal tumor 1 | 3,035
sarcoidosis 1 | 370
sonic hedgehog group medulloblastoma 1 | 467

Tissue

Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Cardiovascular System 4 | 15,192

Target Family

Ion Channel 5 | 344

GO Function

kainate selective glutamate re... 5 | 5
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutamate receptor ionotropic, kainate 4 GRIK4 Tclin Ion Channel -2.19499 147.3 105
Glutamate receptor ionotropic, kainate 5 GRIK5 Tclin Ion Channel -2.11616 127.3 179
Glutamate receptor ionotropic, kainate 1 GRIK1 Tclin Ion Channel -2.44487 279.7 219
Glutamate receptor ionotropic, kainate 2 GRIK2 Tclin Ion Channel -2.43062 278.4 240
Glutamate receptor ionotropic, kainate 3 GRIK3 Tclin Ion Channel -1.52669 31.0 139