Development Level

Tbio 72 | 10,625
Tchem 41 | 1,890
Tclin 14 | 602
Tdark 14 | 7,003

IMPC Term

decreased bone mineral density 3 | 126
decreased grip strength 3 | 123
decreased total body fat amoun... 3 | 186
hyperactivity 3 | 108
preweaning lethality, complete... 3 | 633
preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
abnormal bone structure 2 | 131
abnormal femur morphology 2 | 14
decreased bone mineral content 2 | 157
decreased circulating choleste... 2 | 85
decreased circulating iron lev... 2 | 25
decreased lean body mass 2 | 195
decreased mean platelet volume 2 | 12
improved glucose tolerance 2 | 56
increased circulating alkaline... 2 | 119
increased circulating choleste... 2 | 53
increased or absent threshold ... 2 | 128
small kidney 2 | 10
abnormal behavioral response t... 1 | 52
abnormal clavicle morphology 1 | 5
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal coping response 1 | 12
abnormal craniofacial morpholo... 1 | 12
abnormal cranium morphology 1 | 32
abnormal fibula morphology 1 | 2
abnormal forebrain morphology 1 | 4
abnormal heart left ventricle ... 1 | 20
abnormal hindbrain morphology 1 | 2
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 14
abnormal lens morphology 1 | 73
abnormal limb position 1 | 3
abnormal lumbar vertebrae morp... 1 | 6
abnormal midbrain morphology 1 | 2
abnormal neural tube closure 1 | 37
abnormal pelvic girdle bone mo... 1 | 11
abnormal radius morphology 1 | 8
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal scapula morphology 1 | 3
abnormal skin condition 1 | 6
abnormal thoracic vertebrae mo... 1 | 16
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
abnormal vocalization 1 | 21
absent mammary gland 1 | 1
decreased CD8-positive, alpha-... 1 | 26
decreased IgM level 1 | 1
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased body weight 1 | 174
decreased cardiac muscle contr... 1 | 5
decreased caudal vertebrae num... 1 | 49
decreased cervical vertebrae n... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating calcium ... 1 | 33
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased circulating triglyce... 1 | 83
decreased granulocyte number 1 | 8
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased skeletal muscle mass 1 | 1
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
enlarged spleen 1 | 26
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased B cell number 1 | 23
increased circulating HDL chol... 1 | 63
increased circulating bilirubi... 1 | 16
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased lean body mass 1 | 107
increased lumbar vertebrae num... 1 | 1
increased respiratory quotient 1 | 12
increased rib number 1 | 41
increased startle reflex 1 | 38
increased thoracic vertebrae n... 1 | 8
increased total body fat amoun... 1 | 57
short tibia 1 | 82
shortened QRS complex duration 1 | 1
small heart 1 | 8
small ovary 1 | 1
small spleen 1 | 11
small uterus 1 | 1
thin skin 1 | 1
vertebral transformation 1 | 12

Disease

ovarian cancer 61 | 8,484
psoriasis 61 | 6,685
osteosarcoma 52 | 7,933
medulloblastoma, large-cell 48 | 6,234
lung cancer 39 | 4,466
glioblastoma 34 | 5,572
Cancer 33 | 2,346
non-small cell lung cancer 33 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,289
lung adenocarcinoma 29 | 2,713
lung carcinoma 28 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,956
pancreatic cancer 27 | 2,300
atypical teratoid / rhabdoid tumor 26 | 4,369
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,795
interstitial cystitis 24 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,988
invasive ductal carcinoma 23 | 2,950
Breast cancer 22 | 3,094
malignant mesothelioma 22 | 3,162
pilocytic astrocytoma 22 | 3,086
Prostatic Neoplasms 20 | 471
oligodendroglioma 20 | 2,849
pediatric high grade glioma 20 | 2,712
tuberculosis 20 | 1,557
cystic fibrosis 19 | 1,665
diabetes mellitus 18 | 1,663
ductal carcinoma in situ 18 | 1,745
group 3 medulloblastoma 18 | 2,254
pituitary cancer 18 | 1,972
posterior fossa group A ependymoma 18 | 1,511
subependymal giant cell astrocytoma 18 | 2,287
group 4 medulloblastoma 17 | 1,875
ulcerative colitis 16 | 2,087
adrenocortical carcinoma 15 | 1,427
adult high grade glioma 15 | 2,148
astrocytoma 15 | 1,493
ependymoma 15 | 2,514
primary pancreatic ductal adenocarcinoma 15 | 1,271
primitive neuroectodermal tumor 15 | 3,031
breast carcinoma 14 | 1,614
Hypertension 13 | 287
astrocytic glioma 12 | 2,241
Atopic dermatitis 11 | 944
Multiple myeloma 11 | 1,327
Pick disease 11 | 1,893
active Crohn's disease 11 | 918
Liver disease 10 | 219
atypical teratoid/rhabdoid tumor 10 | 1,095
chronic rhinosinusitis 10 | 512
cutaneous lupus erythematosus 10 | 1,056
mucosa-associated lymphoid tissue lymphoma 10 | 480
Anemia 9 | 252
Kidney disease 9 | 396
Obesity 9 | 616
Thalassemia 9 | 46
acute quadriplegic myopathy 9 | 1,157
Congenital adrenal hyperplasia 8 | 74
Malaria 8 | 140
Schizophrenia 8 | 501
esophageal adenocarcinoma 8 | 737
pancreatic carcinoma 8 | 567
Alzheimer's disease 7 | 644
Carcinoma 7 | 2,147
Drug-Induced Liver Injury 7 | 118
Hemolytic anemia 7 | 66
Lung Neoplasms 7 | 171
Mammary Neoplasms 7 | 410
Peripheral Neuropathy 7 | 303
Vascular disease 7 | 281
aldosterone-producing adenoma 7 | 664
colon cancer 7 | 1,475
periodontitis 7 | 269
sonic hedgehog group medulloblastoma 7 | 1,482
Acute kidney injury 6 | 65
Adenocarcinoma 6 | 115
Adenoma 6 | 165
Antley-Bixler syndrome 6 | 15
Atherosclerosis 6 | 275
Endometriosis 6 | 535
Heart disease 6 | 279
Neurodegenerative disease 6 | 383
Sickle cell anemia 6 | 35
Waldenstrons macroglobulinemia 6 | 765
gastric carcinoma 6 | 832
hepatocellular carcinoma 6 | 532
medulloblastoma 6 | 1,524
nasopharyngeal carcinoma 6 | 1,056
non primary Sjogren syndrome sicca 6 | 840
Duchenne muscular dystrophy 5 | 602
Liver carcinoma 5 | 217
Male infertility 5 | 170
Polycystic Ovary Syndrome 5 | 332
Rheumatoid Arthritis 5 | 1,160
acute myeloid leukemia 5 | 780
dermatomyositis 5 | 933
glioblastoma multiforme 5 | 347
inflammatory breast cancer 5 | 404
juvenile dermatomyositis 5 | 1,189
nephrosclerosis 5 | 329

Tissue

Endocrine System 138 | 18,512
Female tissues 138 | 18,647
Blood and immune system 136 | 17,995
Digestive Tract 136 | 18,473
Liver and Pancreas 136 | 18,136
Nervous System 136 | 18,561
Skin and soft tissues 136 | 18,115
Cardiovascular System 135 | 17,958
Urinary Tract 135 | 18,444
Male tissues 134 | 17,969
Respiratory system 132 | 17,484

Target Family

Enzyme 72 | 4,146
Non-IDG 62 | 11,971
Epigenetic 6 | 242
Transporter 1 | 473

GO Function

iron ion binding 141 | 141
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 OGFOD2 Tdark Enzyme 0.00000 75
24-hydroxycholesterol 7-alpha-hydroxylase CYP39A1 Tbio Enzyme -0.95411 6.43 97
Ferritin heavy chain FTH1 Tbio Non-IDG -2.95630 924.5 435
Ferritin light chain FTL Tbio Non-IDG -2.37909 242.0 430
Lysine-specific demethylase PHF2 PHF2 Tbio Epigenetic -0.67973 5.14 73
Cytochrome P450 4V2 CYP4V2 Tbio Non-IDG -2.66290 481.8 87
Methylcytosine dioxygenase TET1 TET1 Tbio Enzyme -2.91558 843.1 141
Prolyl 4-hydroxylase subunit alpha-1 P4HA1 Tchem Enzyme -1.17728 13.6 143
Arachidonate 15-lipoxygenase B ALOX15B Tchem Enzyme -1.69492 53.8 147
Cytochrome P450 4F22 CYP4F22 Tbio Non-IDG -1.98060 100.6 25