Development Level

Tbio 6 | 11,445
Tchem 4 | 1,598
Tclin 4 | 613
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal joint morphology 1 | 23
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
brachydactyly 1 | 19
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to t... 1 | 278
hydrometra 1 | 53
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74
syndactyly 1 | 23

Disease

Carcinoma 9 | 11,493
lung cancer 6 | 4,740
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
osteosarcoma 5 | 7,950
Astrocytoma, Pilocytic 4 | 3,081
Hypertension 4 | 396
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
ependymoma 4 | 4,679
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
medulloblastoma, large-cell 4 | 6,241
non-small cell lung cancer 4 | 2,890
psoriasis 4 | 6,694
subependymal giant cell astrocytoma 4 | 2,287
Hypertensive disease 3 | 292
Liver Cirrhosis, Experimental 3 | 769
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
ulcerative colitis 3 | 1,819
Atrial Fibrillation 2 | 124
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Edema 2 | 81
Epilepsy 2 | 792
General anesthesia 2 | 53
Hyperaldosteronism 2 | 35
Infantile onset 2 | 238
Liver cancer 2 | 604
Muscle relaxation, function 2 | 8
Nicotine dependence 2 | 54
Pick disease 2 | 1,894
Schizophrenia 2 | 1,160
adrenocortical carcinoma 2 | 1,428
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
gastric carcinoma 2 | 807
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
nasopharyngeal carcinoma 2 | 1,058
ovarian cancer 2 | 8,520
primary Sjogren syndrome 2 | 735
primitive neuroectodermal tumor 2 | 3,035
sonic hedgehog group medulloblastoma 2 | 467
Bartter disease 1 | 13
Birk-Barel syndrome 1 | 8
Bronchiectasis 1 | 64
Bronchitis, Chronic 1 | 12
Central sleep apnea 1 | 11
Cerebral Ischemia 1 | 37
Congenital adrenal hyperplasia 1 | 73
Decreased plasma renin activity 1 | 9
Deglutition Disorders 1 | 132
Dehydration 1 | 40
Dentin sensitivity 1 | 14
Familial primary pulmonary hypertension 1 | 11
Fibrosis 1 | 44
Fused vertebrae 1 | 25
Hepatoblastoma 1 | 19
Hyperactive renin-angiotensin system 1 | 8
Hyperkalemia 1 | 17
Hypertensive disorder 1 | 56
Hypokalemia 1 | 52
Hypomagnesemia 1 | 12
Hypomagnesemia 2, renal 1 | 4
Hypomagnesemia primary 1 | 2
Hypotension 1 | 82
Idiopathic pulmonary arterial hypertension 1 | 40
Increased plasma renin activity 1 | 8
Intracranial hypotension 1 | 10
Kidney damage 1 | 25
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Liddle syndrome 1 | 14
Metabolic acidosis 1 | 90
Myasthenias 1 | 8
Non-immune hydrops fetalis 1 | 11
Oculodentodigital dysplasia 1 | 14
Ophthalmoparesis 1 | 11
Peripheral Edema due to Chronic Heart Failure 1 | 10
Primary hypomagnesemia 1 | 7
Primary hypomagnesemia (disorder) 1 | 2
Primary pulmonary hypertension 1 | 14
Pulmonary Edema due to Chronic Heart Failure 1 | 6
Pulmonary hypertension 1 | 85
Renal salt wasting 1 | 18
Sneddon syndrome 1 | 4
Spinal fusion 1 | 25
Vertebral body fusion 1 | 25
inflammatory breast cancer 1 | 286
non-inflammatory breast cancer 1 | 66
renal hypomagnesemia 3 1 | 2

Tissue

Endocrine System 15 | 18,159
Digestive Tract 14 | 17,369
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Nervous System 13 | 16,725
Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192

Target Family

Ion Channel 12 | 344
Non-IDG 2 | 12,091
Enzyme 1 | 4,145
Transporter 1 | 473

GO Function

ion channel activity 16 | 16
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transient receptor potential cation channel subfamily V member 2 TRPV2 Tchem Ion Channel -2.28525 197.9 203
Sodium/potassium-transporting ATPase subunit gamma FXYD2 Tclin Enzyme -1.58017 39.0 64
Acetylcholine receptor subunit alpha CHRNA1 Tclin Ion Channel -1.66400 41.7 307
Transient receptor potential cation channel subfamily M member 5 TRPM5 Tchem Ion Channel -1.98611 95.5 113
Neuronal acetylcholine receptor subunit alpha-7 CHRFAM7A Tchem Ion Channel -1.81173 87.7 226
Putative FXYD domain-containing ion transport regulator 8 FXYD6P3 Tdark Ion Channel 0.00000 0
Sodium/hydrogen exchanger 10 SLC9C1 Tdark Transporter -2.21216 132.6 11
FXYD domain-containing ion transport regulator 7 FXYD7 Tbio Ion Channel -0.95138 9.06 139
FXYD domain-containing ion transport regulator 5 FXYD5 Tbio Ion Channel -2.63544 427.6 173
Gap junction delta-3 protein GJD3 Tbio Non-IDG -0.48785 4.49 23