Development Level

Tbio 6 | 10,625
Tclin 4 | 602
Tchem 3 | 1,890
Tdark 2 | 7,003

Collection

Eligible Ion Channel Proteins 3 | 117

IMPC Term

abnormal pericardium morpholog... 1 | 11
cardiovascular system phenotyp... 1 | 35
embryonic lethality prior to t... 1 | 187
hydrometra 1 | 13
preweaning lethality, complete... 1 | 633
small superior vagus ganglion 1 | 20

Disease

lung cancer 6 | 4,466
osteosarcoma 5 | 7,933
glioblastoma 4 | 5,572
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
lung adenocarcinoma 4 | 2,713
lung carcinoma 4 | 2,844
medulloblastoma, large-cell 4 | 6,234
non-small cell lung cancer 4 | 2,798
psoriasis 4 | 6,685
sonic hedgehog group medulloblastoma 4 | 1,482
subependymal giant cell astrocytoma 4 | 2,287
Hypertensive disease 3 | 193
adult high grade glioma 3 | 2,148
astrocytic glioma 3 | 2,241
atypical teratoid / rhabdoid tumor 3 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
malignant mesothelioma 3 | 3,162
oligodendroglioma 3 | 2,849
pancreatic cancer 3 | 2,300
pilocytic astrocytoma 3 | 3,086
pituitary cancer 3 | 1,972
posterior fossa group B ependymoma 3 | 1,530
ulcerative colitis 3 | 2,087
Atrial Fibrillation 2 | 110
Cancer 2 | 2,346
General anesthesia 2 | 53
Hypertension 2 | 287
Pick disease 2 | 1,893
adrenocortical carcinoma 2 | 1,427
astrocytoma 2 | 1,493
atypical teratoid/rhabdoid tumor 2 | 1,095
colon cancer 2 | 1,475
cystic fibrosis 2 | 1,665
gastric carcinoma 2 | 832
invasive ductal carcinoma 2 | 2,950
juvenile dermatomyositis 2 | 1,189
nasopharyngeal carcinoma 2 | 1,056
ovarian cancer 2 | 8,484
pediatric high grade glioma 2 | 2,712
primary Sjogren syndrome 2 | 789
primitive neuroectodermal tumor 2 | 3,031
Amyotrophic Lateral Sclerosis 1 | 431
Bartter Disease 1 | 12
Central sleep apnea 1 | 12
Chronic Lymphocytic Leukemia 1 | 242
Chronic heart failure 1 | 46
Congenital adrenal hyperplasia 1 | 74
Congenital myasthenic syndrome 1 | 28
Congestive heart failure 1 | 30
Conn's syndrome 1 | 22
Cystic lymphangioma 1 | 14
Dentin sensitivity 1 | 14
EAST syndrome 1 | 5
Edema 1 | 38
Fibrosis 1 | 40
Gliosis 1 | 16
Heart disease 1 | 279
Hepatoblastoma 1 | 17
Hydrops Fetalis, Non-Immune 1 | 12
Hyperaldosteronism 1 | 27
Hypertensive disorder 1 | 58
Hypotension 1 | 53
Intracranial hypotension 1 | 8
Kidney disease 1 | 396
Leukemia, Myelocytic, Acute 1 | 113
Liddle syndrome 1 | 14
MULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE 1 | 4
Metabolic acidosis 1 | 49
Multiple pterygium syndrome 1 | 17
Nephrocalcinosis 1 | 18
Neuropathy 1 | 210
Neutropenia 1 | 78
Nicotine dependence 1 | 53
Oculodentodigital dysplasia 1 | 14
Peripheral Edema due to Chronic Heart Failure 1 | 10
Poisoning by digitalis glycoside 1 | 8
Primary hypomagnesemia (disorder) 1 | 2
Pseudohypoaldosteronism 1 | 22
Pulmonary Edema due to Chronic Heart Failure 1 | 6
Sinoatrial node disease 1 | 7
Sneddon syndrome 1 | 4
active Crohn's disease 1 | 918
active ulcerative colitis 1 | 477
acute quadriplegic myopathy 1 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
cystic fibrosis and chronic rhinosinusitis 1 | 213
glioblastoma multiforme 1 | 347
inflammatory breast cancer 1 | 404
limb girdle muscular dystrophy 2A 1 | 156
nephrosclerosis 1 | 329
non-inflammatory breast cancer 1 | 208
pancreatic carcinoma 1 | 567
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,795
progressive supranuclear palsy 1 | 674
severe Alzheimer's disease 1 | 49
spina bifida 1 | 1,064
tuberculosis 1 | 1,557
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 13 | 17,995
Cardiovascular System 13 | 17,958
Digestive Tract 13 | 18,473
Endocrine System 13 | 18,512
Female tissues 13 | 18,647
Liver and Pancreas 13 | 18,136
Male tissues 13 | 17,969
Nervous System 13 | 18,561
Respiratory system 13 | 17,484
Skin and soft tissues 13 | 18,115
Urinary Tract 13 | 18,444

Target Family

Ion Channel 11 | 341
Non-IDG 2 | 11,971
Enzyme 1 | 4,146
Transporter 1 | 473

GO Function

ion channel activity 15 | 15
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Amiloride-sensitive sodium channel subunit gamma SCNN1G Tclin Ion Channel -2.03787 117.0 162
Gap junction gamma-1 protein GJC1 Tbio Non-IDG -2.26749 174.8 192
FXYD domain-containing ion transport regulator 6 FXYD6 Tbio Ion Channel -1.08048 14.6 65
Acetylcholine receptor subunit alpha CHRNA1 Tclin Ion Channel -1.59352 37.2 293
Sodium/potassium-transporting ATPase subunit gamma FXYD2 Tclin Enzyme -1.39439 23.9 56
Transient receptor potential cation channel subfamily M member 5 TRPM5 Tchem Ion Channel -1.89870 83.4 103
Transient receptor potential cation channel subfamily V member 2 TRPV2 Tchem Ion Channel -2.21345 186.1 187
P2X purinoceptor 5 P2RX5 Tchem Ion Channel -1.53806 34.9 126
FXYD domain-containing ion transport regulator 7 FXYD7 Tbio Ion Channel -0.79189 6.02 118
Putative FXYD domain-containing ion transport regulator 8 FXYD6P3 Tdark Ion Channel 0.00000 0