Development Level

Tbio 8 | 11,445
Tchem 7 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased mean platelet volume 1 | 25
increased circulating magnesiu... 1 | 10
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
tremors 1 | 39

Disease

Carcinoma 12 | 11,493
psoriasis 10 | 6,694
adult high grade glioma 8 | 3,801
atypical teratoid / rhabdoid tumor 8 | 5,112
group 3 medulloblastoma 8 | 4,104
medulloblastoma, large-cell 8 | 6,241
ependymoma 7 | 4,679
oligodendroglioma 7 | 2,850
primitive neuroectodermal tumor 7 | 3,035
subependymal giant cell astrocytoma 7 | 2,287
Astrocytoma, Pilocytic 6 | 3,081
Schnyder Corneal Dystrophy 6 | 23
gastric carcinoma 6 | 807
glioblastoma 6 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung cancer 6 | 4,740
ovarian cancer 6 | 8,520
Hypokalemia 5 | 52
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
malignant mesothelioma 5 | 3,232
pancreatic cancer 5 | 2,398
Long QT syndrome 4 | 39
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
pituitary cancer 4 | 1,972
Atrial Fibrillation 3 | 124
Autosomal recessive predisposition 3 | 1,442
Breast cancer 3 | 3,578
Brugada syndrome 3 | 29
Cardiac Arrhythmia 3 | 103
Down syndrome 3 | 499
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Familial atrial fibrillation 3 | 23
Intellectual disability 3 | 1,016
Pediatric failure to thrive 3 | 365
Prolonged QT interval 3 | 15
Seizures 3 | 596
Short QT syndrome 3 | 12
Syncope 3 | 22
Ventricular Fibrillation 3 | 17
adrenocortical carcinoma 3 | 1,428
cystic fibrosis 3 | 1,696
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
nephrosclerosis 3 | 333
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 2 | 21
Acquired scoliosis 2 | 281
Alcohol dependence 2 | 107
Arrhythmias, Cardiac 2 | 19
Atopic dermatitis 2 | 952
Atrioventricular block 2 | 35
Big calvaria 2 | 147
Byzanthine arch palate 2 | 194
Cardiac arrest 2 | 36
Cardiomyopathy 2 | 116
Catecholaminergic polymorphic ventricular tachycardia 2 | 12
Curvature of spine 2 | 282
Delayed bone age 2 | 136
Depressive disorder 2 | 409
Elevated plasma renin 2 | 9
Globe of eye large 2 | 20
Hyperaldosteronism 2 | 35
Hypokalemic metabolic alkalosis 2 | 4
Hypokalemic periodic paralysis 2 | 11
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Long QT syndrome 1 2 | 20
Multiple Sclerosis 2 | 540
Nerve Degeneration 2 | 121
Pain agnosia 2 | 104
Palpitations 2 | 18
Parkinson's disease 2 | 392
Pick disease 2 | 1,894
Polydipsia 2 | 15
Polyhydramnios 2 | 108
Polyuria 2 | 23
Renal potassium wasting 2 | 5
Renal salt wasting 2 | 18
Romano-Ward Syndrome 2 | 12
Schizophrenia 2 | 1,160
Sudden Cardiac Death 2 | 29
Sudden infant death syndrome 2 | 32
Timothy syndrome 2 | 11
Torsades de Pointes 2 | 8
Triangular face 2 | 58
active Crohn's disease 2 | 922
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis and chronic rhinosinusitis 2 | 214
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819

Tissue

Endocrine System 17 | 18,159
Nervous System 16 | 16,725
Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Female tissues 15 | 17,400
Skin and soft tissues 15 | 17,230
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Respiratory system 13 | 16,393
Urinary Tract 13 | 16,678
Cardiovascular System 11 | 15,192

Target Family

Ion Channel 17 | 344

GO Function

inward rectifier potassium cha... 17 | 17
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inward rectifier potassium channel 18 KCNJ18 Tdark Ion Channel 0.00000 43
ATP-sensitive inward rectifier potassium channel 14 KCNJ14 Tchem Ion Channel -1.15435 15.5 7
Inward rectifier potassium channel 2 KCNJ2 Tchem Ion Channel -2.36978 224.8 221
Potassium voltage-gated channel subfamily H member 2 KCNH2 Tclin Ion Channel -3.22575 1653.9 243
ATP-sensitive inward rectifier potassium channel 1 KCNJ1 Tchem Ion Channel -2.50371 327.8 188
G protein-activated inward rectifier potassium channel 3 KCNJ9 Tbio Ion Channel -1.46707 27.2 98
Potassium channel subfamily K member 1 KCNK1 Tbio Ion Channel -1.91364 80.5 208
ATP-sensitive inward rectifier potassium channel 8 KCNJ8 Tbio Ion Channel -2.31405 197.3 142
Inward rectifier potassium channel 13 KCNJ13 Tchem Ion Channel -1.75948 58.5 89
Potassium channel subfamily K member 6 KCNK6 Tbio Ion Channel -2.57152 358.7 83