Development Level

Tbio 8 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

abnormal vocalization 1 | 21

Disease

Carcinoma 7 | 11,493
Breast cancer 5 | 3,578
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung cancer 5 | 4,740
psoriasis 5 | 6,694
Kidney cancer 4 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
primitive neuroectodermal tumor 4 | 3,035
Cancer 3 | 2,499
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
Bullous pemphigoid 2 | 18
Carcinoma, Hepatocellular 2 | 228
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Hydrocephalus 2 | 152
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Myopathy 2 | 185
Pediatric failure to thrive 2 | 365
acute myeloid leukemia 2 | 783
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
glioblastoma 2 | 5,792
invasive ductal carcinoma 2 | 2,951
medulloblastoma, large-cell 2 | 6,241
subependymal giant cell astrocytoma 2 | 2,287
Abdominal Pain 1 | 98
Absent eyelashes 1 | 16
Alopecia 1 | 115
Aneurysm 1 | 7
Aneurysmal disease 1 | 6
Aplasia of eyelashes 1 | 16
Arachnodactyly 1 | 49
Arrhythmogenic Right Ventricular Dysplasia, Familial, 9 1 | 1
Arrhythmogenic right ventricular cardiomyopathy 1 | 30
Arrhythmogenic right ventricular cardiomyopathy, type 9 1 | 1
Atrioventricular block 1 | 35
Barrett's esophagus 1 | 182
Big calvaria 1 | 147
Bladder exstrophy 1 | 32
Bone pain 1 | 42
Cardiomyopathy 1 | 116
Cardiomyopathy, Hypertrophic 1 | 24
Cardiomyopathy, right ventricular 1 | 7
Chloracne 1 | 32
Colorectal Neoplasms 1 | 243
Dental caries 1 | 164
Diaphragmatic eventration 1 | 11
Dry skin 1 | 75
Ectodermal Dysplasia 1 | 14
Erythema 1 | 58
Failure of development of eyelashes 1 | 16
Fever 1 | 138
Flushing 1 | 60
Fragile skin 1 | 18
Ganglioneuroma 1 | 13
Hemangioma, Cavernous 1 | 20
Hypertrophic Cardiomyopathy 1 | 117
Immunologic Deficiency Syndromes 1 | 113
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Mask-like facies 1 | 25
Myoclonus 1 | 74
Nail Diseases 1 | 24
Nail abnormality 1 | 22
Narrow face 1 | 54
Neoplasm Metastasis 1 | 168
Nephrosis 1 | 21
Nonepidermolytic palmoplantar keratoderma 1 | 12
Opsoclonus 1 | 5
Palmoplantar keratosis 1 | 74
Palpitations 1 | 18
Panic disorder 1 | 61
Pruritus 1 | 58
Respiratory Distress Syndrome 1 | 15
Respiratory Failure 1 | 104
Skin Ulcer 1 | 48
Skin disease 1 | 66
Sudden Cardiac Death 1 | 29
Syncope 1 | 22
Thin face 1 | 54
VACTERL association 1 | 26
Ventricular aneurysm 1 | 2
Weight decreased 1 | 103
X- linked recessive 1 | 110
Xerosis 1 | 75
non-small cell lung carcinoma 1 | 317
sarcoidosis 1 | 370

Tissue

Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Nervous System 8 | 16,725

Target Family

Non-IDG 7 | 12,091
Kinase 2 | 634
Enzyme 1 | 4,145

GO Function

intermediate filament binding 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Envoplakin-like protein EVPLL Tdark Non-IDG 0.00000 61
Synemin SYNM Tbio Non-IDG -1.91854 92.6 68
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945
Plakophilin-1 PKP1 Tbio Non-IDG -1.86062 76.3 103
Nestin NES Tbio Non-IDG -3.38537 2273.7 741
Epiplakin EPPK1 Tdark Non-IDG -1.29990 21.1 0
Nucleoside diphosphate kinase B NME1-NME2 Tbio Kinase -2.85003 1033.0 85
Myotubularin MTM1 Tbio Enzyme -2.72507 527.3 235
Envoplakin EVPL Tbio Non-IDG -2.45189 261.7 25