Development Level

Tchem 2 | 1,388

IMPC Phenotype

improved glucose tolerance 1 | 79
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased circulating total pr... 1 | 28

Disease

Asthma 2 | 385
Cancer 2 | 2,499
Carcinoma 2 | 11,493
Chronic obstructive pulmonary disease 2 | 184
Colitis, Ulcerative 2 | 59
Mastitis 2 | 48
lung carcinoma 2 | 2,843
osteosarcoma 2 | 7,950
psoriasis 2 | 6,694
ulcerative colitis 2 | 1,819
Actinic keratosis 1 | 21
Acute cystitis 1 | 35
Ankylosing spondylitis 1 | 140
Arthritis 1 | 290
Arthritis, Juvenile 1 | 126
Aspergillosis 1 | 26
Bacteriuria 1 | 8
Blastomycosis 1 | 12
Candidemia 1 | 1
Candidiasis of the esophagus 1 | 1
Chronic NK-cell lymphocytosis 1 | 6
Denture stomatitis 1 | 11
Disseminated candidiasis 1 | 4
Dysmenorrhea 1 | 21
Fungal Infection due to Fusarium Solani 1 | 1
Fungal Infection due to Scedosporium Apiospermum 1 | 1
Fusarium infection 1 | 1
HIV Infections 1 | 102
Histoplasmosis 1 | 13
Human immunodeficiency virus type 1, susceptibility to 1 | 26
Hypersensitivity 1 | 63
Hypertension 1 | 396
Infarction, Middle Cerebral Artery 1 | 33
Inflammatory bowel disease 1 | 151
Invasive pulmonary aspergillosis 1 | 1
Juvenile arthritis 1 | 126
Onychomycosis of fingernails 1 | 2
Onychomycosis of toenails 1 | 2
Oropharyngeal Candidiasis 1 | 3
Osteoarthritis 1 | 184
Osteoarthritis in Patients at High Ulcer Risk 1 | 7
Osteoarthrosis of the Knee 1 | 4
Pain 1 | 103
Pneumonia 1 | 174
Post-Op Ocular Inflammation 1 | 9
Post-Op Photophobia 1 | 4
Postoperative Ocular Pain 1 | 5
Pyelonephritis 1 | 13
Rheumatoid Arthritis in Patient at High Ulcer Risk 1 | 7
Rheumatoid arthritis 1 | 1,191
Sepsis 1 | 24
Sprains and Strains 1 | 6
Vascular Remodeling 1 | 3
Vascular disease 1 | 319
colon cancer 1 | 1,478
cutaneous lupus erythematosus 1 | 1,057
esophageal adenocarcinoma 1 | 737
hepatocellular carcinoma 1 | 547
lung adenocarcinoma 1 | 2,716
lung cancer 1 | 4,740
mucosa-associated lymphoid tissue lymphoma 1 | 484
non-small cell lung cancer 1 | 2,890
non-small cell lung carcinoma 1 | 317
ovarian cancer 1 | 8,520
pancreatic cancer 1 | 2,398
pancreatic carcinoma 1 | 562
tuberculosis 1 | 2,010
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

GPCR 2 | 408

GO Function

interleukin-8 receptor activit... 2 | 2
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-X-C chemokine receptor type 1 CXCR1 Tchem GPCR -2.48051 278.1 378
C-X-C chemokine receptor type 2 CXCR2 Tchem GPCR -2.87313 723.9 643