Development Level

Tchem 6 | 1,598
Tclin 2 | 613
Tbio 1 | 11,445

IMPC Phenotype

abnormal coat-hair pigmentatio... 1 | 64
abnormal lung morphology 1 | 26
abnormal urinary bladder morph... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
enlarged heart 1 | 210
short tibia 1 | 97

Disease

Cancer 9 | 2,499
glioblastoma 8 | 5,792
medulloblastoma, large-cell 8 | 6,241
ovarian cancer 8 | 8,520
ependymoma 7 | 4,679
pancreatic cancer 7 | 2,398
atypical teratoid / rhabdoid tumor 6 | 5,112
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
psoriasis 6 | 6,694
Breast cancer 5 | 3,578
Obesity 5 | 678
adrenocortical carcinoma 5 | 1,428
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
pituitary cancer 5 | 1,972
Astrocytoma, Pilocytic 4 | 3,081
Carcinoma 4 | 11,493
Hyperinsulinism 4 | 133
Hypoglycemia 4 | 152
dermatomyositis 4 | 966
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
oligodendroglioma 4 | 2,850
osteosarcoma 4 | 7,950
pediatric high grade glioma 4 | 1,064
primitive neuroectodermal tumor 4 | 3,035
Abortion, Spontaneous 3 | 109
Acromegaly 3 | 51
Autosomal recessive predisposition 3 | 1,442
Duchenne muscular dystrophy 3 | 601
Hyperglycemia 3 | 137
Liver Cirrhosis, Experimental 3 | 769
Polycystic ovary syndrome 3 | 360
Spontaneous abortion 3 | 113
adult high grade glioma 3 | 3,801
astrocytoma 3 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
esophageal adenocarcinoma 3 | 737
group 4 medulloblastoma 3 | 1,855
juvenile dermatomyositis 3 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Abdomen distended 2 | 43
Acquired metabolic disease 2 | 336
Alzheimer Disease 2 | 83
Alzheimer's disease 2 | 658
Anorexia nervosa 2 | 80
Arthritis, Rheumatoid 2 | 174
Becker muscular dystrophy 2 | 191
Bladder Neoplasm 2 | 112
Breast Neoplasms 2 | 445
Congenital anomaly of face 2 | 56
Congenital diaphragmatic hernia 2 | 67
Contact Dermatitis 2 | 81
Delayed bone age 2 | 136
Dermatitis, Contact 2 | 71
Distortion of face 2 | 46
Dysmorphic facies 2 | 46
Endometriosis 2 | 540
Fetal Growth Retardation 2 | 189
Funny looking face 2 | 46
Gout 2 | 106
Hyperandrogenism 2 | 34
Hypothyroidism 2 | 122
Infant, Small for Gestational Age 2 | 176
Insulin Resistance 2 | 72
Intrauterine retardation 2 | 176
Kidney disease 2 | 430
Liver Cirrhosis 2 | 181
Lung diseases 2 | 50
Mammary Neoplasms 2 | 425
Nail dysplasia 2 | 52
Parkinson Disease 2 | 64
Peripheral Neuropathy 2 | 134
Prenatal onset 2 | 139
Prostatic Neoplasms 2 | 495
Rheumatoid arthritis 2 | 1,191
Short stature 2 | 531
Silver-Russell syndrome 2 | 39
Urinary Bladder Neoplasms 2 | 114
active Crohn's disease 2 | 922
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
facial deformity 2 | 46
fibroadenoma 2 | 559
interstitial lung disease 2 | 298
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 7 | 12,091
Kinase 2 | 634

GO Function

insulin-like growth factor I b... 9 | 9
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Insulin-like growth factor-binding protein 5 IGFBP5 Tchem Non-IDG -2.52721 351.8 278
Insulin-like growth factor-binding protein 2 IGFBP2 Tchem Non-IDG -2.93237 835.0 335
Insulin-like growth factor 1 receptor IGF1R Tclin Kinase -3.37168 2419.5 1686
Insulin receptor INSR Tclin Kinase -2.50045 306.8 1417
Integrin alpha-6 ITGA6 Tbio Non-IDG -2.30127 180.4 944
Insulin-like growth factor-binding protein 6 IGFBP6 Tchem Non-IDG -2.07870 126.1 254
Insulin-like growth factor-binding protein 3 IGFBP3 Tchem Non-IDG -3.35760 2176.5 510
Insulin-like growth factor-binding protein 1 IGFBP1 Tchem Non-IDG -3.07028 1156.1 425
Insulin-like growth factor-binding protein 4 IGFBP4 Tchem Non-IDG -2.48513 285.8 416