Development Level

Tbio 7 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
increased lymphocyte cell numb... 1 | 32
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
tremors 1 | 39

Disease

Carcinoma 8 | 11,493
Oculocerebrorenal syndrome 6 | 29
adult high grade glioma 5 | 3,801
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
ovarian cancer 4 | 8,520
Astrocytoma, Pilocytic 3 | 3,081
Intellectual disability 3 | 1,016
Pick disease 3 | 1,894
astrocytoma 3 | 1,146
lung carcinoma 3 | 2,843
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Acquired scoliosis 2 | 281
Autosomal recessive predisposition 2 | 1,442
Cataract 2 | 297
Cryptorchidism 2 | 296
Curvature of spine 2 | 282
Dent disease 2 | 18
Dull intelligence 2 | 645
Epilepsy 2 | 792
Frontal bossing 2 | 157
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Poor school performance 2 | 645
Seizures 2 | 596
active Crohn's disease 2 | 922
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
group 4 medulloblastoma 2 | 1,855
lung adenocarcinoma 2 | 2,716
oligodendroglioma 2 | 2,850
spina bifida 2 | 1,074
Abnormal urinary amino-acid findings 1 | 38
Abnormality of the fingernails 1 | 51
Abnormality of the renal tubule 1 | 7
Adult Fanconi syndrome 1 | 12
Aminoaciduria 1 | 38
Calcinosis 1 | 70
Chronic Kidney Diseases 1 | 13
Clonus 1 | 18
Defective enamel matrix 1 | 35
Dehydration 1 | 40
Dental Enamel Hypoplasia 1 | 43
Dysphasia 1 | 23
Dysplasia of tooth enamel 1 | 35
Edema 1 | 81
Fine hair 1 | 42
Gait, Shuffling 1 | 8
Generalized hypopigmentation 1 | 12
Hooked clavicle 1 | 5
Hypercalciuria 1 | 27
Hyperkyphosis 1 | 111
Hyperphosphaturia 1 | 21
Hypokalemia 1 | 52
Hypophonia 1 | 7
Hypoplastic ilia 1 | 12
Hypoplastic ischia 1 | 11
Hypoplastic pubic bone 1 | 7
Hypoplastic toenails 1 | 22
Joint swelling 1 | 26
Kyphosis deformity of spine 1 | 114
Lymphatic obstruction 1 | 21
MUSCULAR DYSTROPHY, CONGENITAL, WITH CATARACTS AND INTELLECTUAL DISABILITY 1 | 1
Malignant neoplasm of skin 1 | 15
Metabolic Syndrome 1 | 20
Muscle Rigidity 1 | 49
Obsessive compulsive behavior 1 | 25
Onset of lymphedema around puberty 1 | 21
Platyspondyly 1 | 56
Postural instability 1 | 19
Progressive renal failure 1 | 13
Pyramidal sign 1 | 29
Reduced visual acuity 1 | 63
Renal glomerular disease 1 | 12
Resting Tremor 1 | 9
Retinopathy of prematurity 1 | 22
Self-Injurious Behavior 1 | 12
Serum cholesterol raised 1 | 22
Short hands 1 | 50
Short ribs 1 | 30
Short tubular bones 1 | 22
Shuffling, short-stepped gait 1 | 5
Skin Neoplasms 1 | 69
Small wings of the pelvic girdle 1 | 12
Sparse scalp hair 1 | 42
Spinocerebellar ataxia type 2 1 | 23
Supranuclear gaze palsy 1 | 6
Thin dental enamel 1 | 35
Urine phosphorous concentration above normal 1 | 21
Voice Fatigue 1 | 7
X- linked recessive 1 | 110

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Enzyme 7 | 4,145
Kinase 1 | 634
Non-IDG 1 | 12,091

GO Function

inositol-1,3,4,5-tetrakisphosp... 9 | 9
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synaptojanin-1 SYNJ1 Tbio Non-IDG -1.76329 62.0 93
Type II inositol 1,4,5-trisphosphate 5-phosphatase INPP5B Tbio Enzyme -1.53163 29.3 109
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 INPPL1 Tchem Enzyme -2.05056 144.2 215
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 INPP5D Tbio Enzyme -2.06945 104.7 374
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A INPP5J Tbio Enzyme -1.87182 73.3 126
Inositol-tetrakisphosphate 1-kinase ITPK1 Tbio Kinase -1.38434 24.8 201
Inositol polyphosphate 5-phosphatase K INPP5K Tbio Enzyme -0.93536 10.1 92
Inositol polyphosphate 5-phosphatase OCRL-1 OCRL Tbio Enzyme -2.20394 172.2 226
Type I inositol 1,4,5-trisphosphate 5-phosphatase INPP5A Tchem Enzyme -1.32753 19.3 109