Development Level

Tbio 5 | 11,445
Tchem 5 | 1,598

IMPC Phenotype

abnormal forelimb morphology 1 | 2
abnormal gait 1 | 69
abnormal locomotor activation 1 | 16
abnormal response to new envir... 1 | 10
corneal vascularization 1 | 6
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating glycerol... 1 | 16
decreased circulating triglyce... 1 | 79
decreased prepulse inhibition 1 | 82
hyperactivity 1 | 148
increased lean body mass 1 | 172
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
mammalian phenotype 1 | 17
preweaning lethality, complete... 1 | 979
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 10 | 11,493
lung cancer 7 | 4,740
Kidney cancer 6 | 2,613
atypical teratoid / rhabdoid tumor 6 | 5,112
Hypertension 5 | 396
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
Breast cancer 4 | 3,578
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
medulloblastoma, large-cell 4 | 6,241
psoriasis 4 | 6,694
subependymal giant cell astrocytoma 4 | 2,287
Astrocytoma, Pilocytic 3 | 3,081
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
primitive neuroectodermal tumor 3 | 3,035
Alzheimer's disease 2 | 658
Down syndrome 2 | 499
Endometriosis 2 | 540
Hypertensive disease 2 | 292
Liver cancer 2 | 604
Pick disease 2 | 1,894
adrenocortical carcinoma 2 | 1,428
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
group 4 medulloblastoma 2 | 1,855
head and neck cancer 2 | 271
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
progressive supranuclear palsy 2 | 676
substance-related disorder 2 | 162
Adult onset 1 | 82
Amenorrhea Secondary to Ovarian Dysfunction 1 | 8
Atrophic vaginitis 1 | 14
Atrophy of cerebellum 1 | 103
Autistic Disorder 1 | 364
Autosomal dominant cerebellar ataxia 1 | 33
Barrett's esophagus 1 | 182
Bipolar Disorder 1 | 666
Cancer 1 | 2,499
Cardiomegaly 1 | 116
Cerebellar degeneration 1 | 103
Chronic obstructive pulmonary disease 1 | 184
Contraception 1 | 15
Corpus Luteum Insufficiency Syndrome 1 | 8
DOID:2627 1 | 94
Disease of anatomical entity 1 | 32
Duchenne muscular dystrophy 1 | 601
Dysfunctional uterine bleeding 1 | 9
Endometrial Hyperplasia Prevention 1 | 9
Endometrial cancer 1 | 311
Endometrial carcinoma 1 | 15
Focal glomerulosclerosis 1 | 37
Glomerulosclerosis, Focal Segmental 1 | 28
Griscelli syndrome 1 | 24
Infertility Secondary to Progesterone Deficiency 1 | 8
Infratentorial atrophy 1 | 103
Intracranial aneurysm 1 | 24
Kidney disease 1 | 430
Megalocornea 1 | 13
Melanoma 1 | 711
Menopausal flushing 1 | 17
Neurodegenerative disease 1 | 414
Osteoporosis 1 | 363
Polycystic kidney disease 1 1 | 21
Polycystic kidney disease 2 1 | 11
Postmenopausal osteoporosis 1 | 19
Prevention of Premature Labor 1 | 9
Progressive disorder 1 | 142
Prostate cancer 1 | 175
Proteinuria 1 | 144
Secondary malignant neoplasm of kidney 1 | 9
Secondary physiologic amenorrhea 1 | 32
Skin cancer 1 | 469
Spinocerebellar Ataxias 1 | 34
Thyrotoxicosis 1 | 38
Waldenstrons macroglobulinemia 1 | 765
aldosterone-producing adenoma 1 | 665
atypical teratoid/rhabdoid tumor 1 | 357
breast carcinoma 1 | 1,638
facioscapulohumeral dystrophy 1 | 288
pancreatic carcinoma 1 | 562
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pituitary cancer 1 | 1,972
posterior fossa group B ependymoma 1 | 416
sonic hedgehog group medulloblastoma 1 | 467
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409

Tissue

Liver and Pancreas 10 | 16,750
Nervous System 10 | 16,725
Urinary Tract 10 | 16,678
Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Male tissues 9 | 17,142
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Cardiovascular System 8 | 15,192

Target Family

Ion Channel 6 | 344
Enzyme 2 | 4,145
Epigenetic 1 | 242
Non-IDG 1 | 12,091

GO Function

inositol 1,4,5 trisphosphate b... 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inactive phospholipase C-like protein 2 PLCL2 Tbio Enzyme -0.30556 2.11 96
Short transient receptor potential channel 1 TRPC1 Tbio Ion Channel -2.52589 340.7 162
Inactive phospholipase C-like protein 1 PLCL1 Tbio Enzyme -2.22526 167.9 97
Cytohesin-2 CYTH2 Tbio Non-IDG -1.72707 0.00000 220
Inositol 1,4,5-trisphosphate receptor type 3 ITPR3 Tchem Ion Channel -2.51894 316.1 127
Short transient receptor potential channel 6 TRPC6 Tchem Ion Channel -2.82303 661.6 320
Short transient receptor potential channel 3 TRPC3 Tchem Ion Channel -2.46704 294.6 217
Short transient receptor potential channel 5 TRPC5 Tchem Ion Channel -2.25002 172.0 220
Rabphilin-3A RPH3A Tbio Epigenetic -1.78352 69.1 198
Short transient receptor potential channel 4 TRPC4 Tchem Ion Channel -2.28183 190.1 229