Development Level

Tbio 3 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
anophthalmia 1 | 33
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased prepulse inhibition 1 | 32
microphthalmia 1 | 26
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 4 | 11,493
Kidney cancer 4 | 2,613
Breast cancer 3 | 3,578
Pre-Eclampsia 3 | 68
interstitial cystitis 3 | 2,312
ovarian cancer 3 | 8,520
ulcerative colitis 3 | 1,819
Astrocytoma, Pilocytic 2 | 3,081
Cancer 2 | 2,499
Liver cancer 2 | 604
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
invasive ductal carcinoma 2 | 2,951
osteosarcoma 2 | 7,950
pituitary cancer 2 | 1,972
psoriasis 2 | 6,694
tuberculosis 2 | 2,010
Abortion, Spontaneous 1 | 109
Autosomal recessive Robinow syndrome 1 | 27
Carcinoma of pancreas 1 | 5
Congenital hypothyroidism 1 | 26
Congenital myasthenic syndrome 4C 1 | 9
Down syndrome 1 | 499
Edwards syndrome 1 | 17
Familial Testotoxicosis 1 | 3
Fibroid Tumor 1 | 6
HYPOTHYROIDISM, CENTRAL, AND TESTICULAR ENLARGEMENT 1 | 1
Hypopituitarism 1 | 40
Hypothyroidism 1 | 122
Juvenile absence epilepsy 1 | 8
Leiomyoma 1 | 32
Liver Failure, Acute 1 | 29
Melanoma 1 | 711
Microsatellite Instability 1 | 12
Multiple synostoses syndrome 1 | 9
Premature ovarian failure 1 | 65
Skin cancer 1 | 469
Spontaneous abortion 1 | 113
Testicular Diseases 1 | 4
Uterine Neoplasms 1 | 9
X- linked recessive 1 | 110
X-linked cerebral adrenoleukodystrophy 1 | 116
acute myeloid leukemia 1 | 783
colon cancer 1 | 1,478
cystic fibrosis 1 | 1,696
ductal carcinoma in situ 1 | 1,745
gastric carcinoma 1 | 807
group 4 medulloblastoma 1 | 1,855
head and neck cancer 1 | 271
lung adenocarcinoma 1 | 2,716
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
malignant mesothelioma 1 | 3,232
medulloblastoma 1 | 720
nasopharyngeal carcinoma 1 | 1,058
ovarian adenocarcinoma 1 | 1
pancreatic cancer 1 | 2,398
permanent atrial fibrillation 1 | 45
primary Sjogren syndrome 1 | 735
primary pancreatic ductal adenocarcinoma 1 | 1,109

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Non-IDG 3 | 12,091
Kinase 2 | 634

GO Function

inhibin binding 5 | 5
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Activin receptor type-1B ACVR1B Tchem Kinase -2.00550 91.2 418
Immunoglobulin superfamily member 1 IGSF1 Tbio Non-IDG -1.62840 43.8 149
Inhibin beta A chain INHBA Tbio Non-IDG -1.92108 76.6 319
Inhibin alpha chain INHA Tbio Non-IDG -2.40544 248.6 478