Development Level

Tbio 8 | 11,651
Tchem 1 | 1,388
Tclin 1 | 612
Tdark 1 | 6,593

IMPC Phenotype

decreased startle reflex 2 | 75
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
corneal opacity 1 | 32
decreased grip strength 1 | 116
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
hyperactivity 1 | 148
hypoactivity 1 | 132
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
limb grasping 1 | 41

Disease

Carcinoma 7 | 11,493
ependymoma 6 | 4,679
glioblastoma 6 | 5,792
medulloblastoma, large-cell 6 | 6,241
osteosarcoma 6 | 7,950
Astrocytoma, Pilocytic 5 | 3,081
astrocytic glioma 5 | 2,597
invasive ductal carcinoma 5 | 2,951
oligodendroglioma 5 | 2,850
ovarian cancer 5 | 8,520
Intellectual disability 4 | 1,016
atypical teratoid / rhabdoid tumor 4 | 5,112
group 3 medulloblastoma 4 | 4,104
interstitial cystitis 4 | 2,312
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
primitive neuroectodermal tumor 4 | 3,035
psoriasis 4 | 6,694
ulcerative colitis 4 | 1,819
Atopic dermatitis 3 | 952
Breast cancer 3 | 3,578
Pick disease 3 | 1,894
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
Obesity 2 | 678
Seizures 2 | 596
active ulcerative colitis 2 | 764
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
fibroadenoma 2 | 559
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010
Abnormal vision 1 | 52
Abnormal visual evoked potential 1 | 26
Amenorrhea 1 | 58
Amnestic disorder 1 | 35
Angelman syndrome 1 | 34
Argininosuccinic aciduria 1 | 17
Asthma, susceptibility to 1 | 11
Body dysmorphic disorder 1 | 11
Breast Neoplasms 1 | 445
COPD 1 | 118
Canavan disease 1 | 10
Carcinoma, Renal Cell 1 | 124
Central nervous system demyelination 1 | 28
Chromosome 1p36 deletion syndrome 1 | 23
Chromosome 9p deletion syndrome 1 | 13
Cocaine abuse 1 | 19
Comatose 1 | 56
Coronary Disease 1 | 25
Cri-Du-Chat syndrome 1 | 16
Deglutition Disorders 1 | 132
DiGeorge syndrome 1 | 47
Drug-Related Side Effects and Adverse Reactions 1 | 62
Factor XII deficiency 1 | 13
Hepatitis 1 | 67
Hyperactive behavior 1 | 91
Hyperkinesis 1 | 32
Hypersensitivity, Immediate 1 | 8
Hypertriglyceridemia 1 | 17
Hypospadias 1 | 53
IgE RESPONSIVENESS, ATOPIC 1 | 8
Immediate hypersensitivity 1 | 8
Imperforate anus 1 | 25
Lethargy 1 | 77
Leukocoria 1 | 10
Leukodystrophy 1 | 55
Microphthalmia 1 | 76
Mild global developmental delay 1 | 14
Muscular Dystrophies 1 | 8
Muscular fasciculation 1 | 22
Myasthenia gravis 1 | 23
Neurotoxicity Syndromes 1 | 26
Opioid abuse 1 | 5
Paralysed 1 | 42
Paralysis 1 | 9
Poisoning 1 | 16
Prader-Willi syndrome 1 | 48
Psychomotor retardation, mild 1 | 14
Renal Cell Carcinoma 1 | 214
Retinitis pigmentosa 23 1 | 27
Retinoblastoma 1 | 19
Sialuria 1 | 9
Sleep Apnea Syndromes 1 | 13
Sleep disturbances 1 | 37
Wilson disease 1 | 16
Wolf-Hirschhorn syndrome 1 | 32
non-small cell lung carcinoma 1 | 317
sarcoidosis 1 | 370

Tissue

Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Cardiovascular System 10 | 15,192

Target Family

Enzyme 10 | 4,145
Non-IDG 1 | 12,091

GO Function

hydrolase activity, acting on ... 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ester hydrolase C11orf54 C11orf54 Tbio Enzyme -0.36001 2.22 46
Aspartoacylase ASPA Tbio Enzyme -2.04271 107.1 151
Cholinesterase BCHE Tclin Enzyme -3.34790 2272.5 276
S-formylglutathione hydrolase ESD Tbio Enzyme -2.32609 210.3 140
Phosphotriesterase-related protein PTER Tbio Enzyme -2.99001 948.7 83
Lipase member J LIPJ Tbio Enzyme -0.76592 6.31 71
N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) ACY3 Tbio Enzyme -0.86435 6.57 152
GPI inositol-deacylase PGAP1 Tbio Enzyme -1.11041 12.5 25
Post-GPI attachment to proteins factor 3 PGAP3 Tbio Non-IDG -1.44616 29.4 135
Protein ABHD15 ABHD15 Tdark Enzyme 0.70 0.00000 39