Development Level

Tbio 37 | 11,445
Tdark 34 | 6,588
Tchem 7 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal seminal vesicle morph... 2 | 114
increased bone mineral density 2 | 72
increased lean body mass 2 | 172
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal eye morphology 1 | 68
abnormal hair growth 1 | 10
abnormal retina morphology 1 | 71
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
decreased body length 1 | 101
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating lipase l... 1 | 3
decreased circulating potassiu... 1 | 20
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased vertical activity 1 | 208
enlarged seminal vesicle 1 | 10
enlarged testis 1 | 6
hydrometra 1 | 53
hyperactivity 1 | 148
impaired righting response 1 | 26
increased body length 1 | 32
increased caudal vertebrae num... 1 | 7
increased circulating alkaline... 1 | 122
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
male infertility 1 | 123
microphthalmia 1 | 26
preweaning lethality, complete... 1 | 979
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Carcinoma 35 | 11,493
ovarian cancer 29 | 8,520
osteosarcoma 22 | 7,950
glioblastoma 20 | 5,792
psoriasis 20 | 6,694
atypical teratoid / rhabdoid tumor 18 | 5,112
medulloblastoma, large-cell 17 | 6,241
group 3 medulloblastoma 16 | 4,104
ependymoma 15 | 4,679
adult high grade glioma 14 | 3,801
lung cancer 13 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Breast cancer 12 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
group 4 medulloblastoma 11 | 1,855
lung carcinoma 11 | 2,843
malignant mesothelioma 11 | 3,232
non-small cell lung cancer 11 | 2,890
oligodendroglioma 11 | 2,850
pancreatic cancer 11 | 2,398
Astrocytoma, Pilocytic 10 | 3,081
ductal carcinoma in situ 10 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
primitive neuroectodermal tumor 10 | 3,035
invasive ductal carcinoma 9 | 2,951
astrocytic glioma 8 | 2,597
cystic fibrosis 8 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
pituitary cancer 8 | 1,972
tuberculosis 8 | 2,010
colon cancer 7 | 1,478
interstitial cystitis 7 | 2,312
lung adenocarcinoma 7 | 2,716
Autosomal recessive predisposition 6 | 1,442
Pick disease 6 | 1,894
breast carcinoma 6 | 1,638
diabetes mellitus 6 | 1,728
pediatric high grade glioma 6 | 1,064
Bipolar Disorder 5 | 666
Prostatic Neoplasms 5 | 495
Schizophrenia 5 | 1,160
acute quadriplegic myopathy 5 | 1,158
astrocytoma 5 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
nasopharyngeal carcinoma 5 | 1,058
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Cancer 4 | 2,499
Duchenne muscular dystrophy 4 | 601
Kidney cancer 4 | 2,613
esophageal adenocarcinoma 4 | 737
fibroadenoma 4 | 559
gastric cancer 4 | 459
hepatocellular carcinoma 4 | 547
inflammatory breast cancer 4 | 286
juvenile dermatomyositis 4 | 1,187
non primary Sjogren syndrome sicca 4 | 891
pancreatic carcinoma 4 | 562
posterior fossa group A ependymoma 4 | 468
Abnormality of metabolism/homeostasis 3 | 134
Alzheimer's disease 3 | 658
Atopic dermatitis 3 | 952
Creatine phosphokinase serum increased 3 | 110
Crohn's disease 3 | 321
Elevated creatine kinase 3 | 110
Parkinson's disease 3 | 392
Seizures 3 | 596
acute myeloid leukemia 3 | 783
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
non-small cell lung carcinoma 3 | 317
spina bifida 3 | 1,074
tuberculosis and treatment for 3 months 3 | 179
Amphetamine-Related Disorders 2 | 74
Becker muscular dystrophy 2 | 191
Cardiovascular system disease 2 | 246
Epilepsy 2 | 792
Frontal bossing 2 | 157
Kidney Failure 2 | 111
Liver Cirrhosis, Experimental 2 | 769
Myopathy 2 | 185
Neuropathy 2 | 261
Polycystic ovary syndrome 2 | 360
Progressive disorder 2 | 142
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Stomach Neoplasms 2 | 300
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
atypical teratoid/rhabdoid tumor 2 | 357
gastric carcinoma 2 | 807
head and neck cancer 2 | 271
limb girdle muscular dystrophy 2A 2 | 213
medulloblastoma 2 | 720
periodontitis 2 | 293
posterior fossa group B ependymoma 2 | 416
progressive supranuclear palsy 2 | 676
pterygium 2 | 76

Tissue

Female tissues 78 | 17,400
Digestive Tract 77 | 17,369
Endocrine System 77 | 18,159
Male tissues 77 | 17,142
Skin and soft tissues 77 | 17,230
Blood and immune system 76 | 16,909
Liver and Pancreas 75 | 16,750
Nervous System 75 | 16,725
Urinary Tract 75 | 16,678
Respiratory system 72 | 16,393
Cardiovascular System 71 | 15,192

Target Family

Enzyme 57 | 4,145
Non-IDG 21 | 12,091
Kinase 2 | 634

GO Function

hydrolase activity 80 | 80
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HRAS-like suppressor 2 HRASLS2 Tbio Non-IDG -0.19299 1.65 72
Phospholipid-metabolizing enzyme A-C1 HRASLS Tbio Non-IDG -0.89072 8.53 0
Protein ABHD14A ABHD14A Tdark Enzyme 0.23 0.52 90
AFG1-like ATPase AFG1L Tbio Non-IDG -2.05946 114.5 134
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 ENPP5 Tdark Enzyme -0.64428 4.38 121
Nucleoside diphosphate-linked moiety X motif 22 NUDT22 Tdark Non-IDG 0.00000 0.00000 72
Serine/threonine-protein kinase RIO1 RIOK1 Tchem Kinase -0.83569 7.38 159
Nucleoside diphosphate-linked moiety X motif 8 NUDT8 Tdark Non-IDG 0.00000 101
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 NDST3 Tbio Enzyme -0.66930 5.78 111
NADPH--cytochrome P450 reductase POR Tbio Enzyme -2.43541 216.2 257