Development Level

Tbio 10 | 11,651
Tdark 4 | 6,593
Tchem 3 | 1,388

IMPC Phenotype

abnormal coat appearance 1 | 31
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating alkaline... 1 | 122
narrow eye opening 1 | 12
preweaning lethality, complete... 1 | 979
small adrenal glands 1 | 16
small lymph nodes 1 | 1

Disease

ovarian cancer 8 | 8,520
Carcinoma 7 | 11,493
osteosarcoma 6 | 7,950
psoriasis 5 | 6,694
medulloblastoma, large-cell 4 | 6,241
Multiple myeloma 3 | 1,332
astrocytic glioma 3 | 2,597
lung cancer 3 | 4,740
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
3-methylglutaconic aciduria 2 | 29
Anemia 2 | 365
Autosomal recessive predisposition 2 | 1,442
Cardiomyopathy 2 | 116
Cerebellar Ataxia 2 | 304
Leigh disease 2 | 100
Mitochondrial myopathy 2 | 26
Parkinson's disease 2 | 392
Pneumonia 2 | 174
Sensorineural Hearing Loss (disorder) 2 | 284
Waldenstrons macroglobulinemia 2 | 765
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
ulcerative colitis 2 | 1,819
ANONYCHIA 1 | 20
Abnormal vision 1 | 52
Aceruloplasminemia 1 | 16
Acute lymphoid leukemia 1 | 25
Adenocarcinoma of lung (disorder) 1 | 60
Anemia, Iron-Deficiency 1 | 4
Anterior hypopituitarism 1 | 18
Blind spot located at fixation point 1 | 21
Blurred vision 1 | 19
Burkitt's lymphoma 1 | 15
Bushy eyebrows 1 | 49
Carcinoma of female breast 1 | 20
Central retinal vessel vascular tortuosity 1 | 9
Congenital defect of folate absorption 1 | 1
Decreased visual acuity, slowly progressive 1 | 13
Deep philtrum 1 | 21
Depressed philtrum 1 | 21
Diphyllobothriasis 1 | 6
Echinococcosis 1 | 26
Enamel erosion 1 | 19
Enlarged vestibular aqueduct 1 | 10
Fatal familial insomnia 1 | 10
Folate Malabsorption, Hereditary 1 | 1
Folic acid deficiency anemia 1 | 1
Gestational trophoblastic neoplasia 1 | 14
Glucose Intolerance 1 | 19
HYPERGLYCINURIA (disorder) 1 | 12
Heart Diseases 1 | 43
Hemochromatosis 1 | 54
Hyperglycinuria 1 | 3
Hypertrophy 1 | 17
Iminoglycinuria 1 | 4
Impaired glucose tolerance 1 | 28
Iron deficiency anemia 1 | 12
Juvenile rheumatoid arthritis 1 | 111
Kearns-Sayre syndrome 1 | 7
Leber hereditary optic neuropathy 1 | 14
Leber's optic atrophy 1 | 10
Leigh syndrome 1 | 28
Malabsorption Syndrome 1 | 1
Malabsorption Syndromes 1 | 1
Malignant mesothelioma of pleura 1 | 7
Malignant tumor of head and/or neck 1 | 15
Malignant tumor of lung 1 | 5
Meningeal Leukemia 1 | 7
Metabolic acidosis 1 | 90
Micronychia (disorder) 1 | 24
Mitochondrial Myopathies 1 | 21
Mitochondrial respiratory chain defects 1 | 15
Mycosis fungoides 1 | 29
Non-Hodgkin's lymphoma 1 | 22
Optic Atrophy, Hereditary, Leber 1 | 14
Optic Neuropathy 1 | 12
Osteosarcoma of bone 1 | 6
Peripheral Neuropathy 1 | 134
Pigmented villonodular synovitis 1 | 9
Polyneuropathy 1 | 64
RENAL TUBULAR ACIDOSIS, DISTAL, AUTOSOMAL RECESSIVE 1 | 3
Ragged-red fibers 1 | 21
Renal Tubular Acidosis, Distal, with Progressive Nerve Deafness 1 | 1
Retinal telangiectasia 1 | 12
STRIATONIGRAL DEGENERATION, INFANTILE (disorder) 1 | 3
Salt and pepper retinal pigmentation 1 | 8
Scotoma, Central 1 | 21
Scotoma, Centrocecal 1 | 11
Sensory neuropathy 1 | 20
Slow decrease in visual acuity 1 | 13
Static Tremor 1 | 21
Striatonigral Degeneration, Infantile 1 | 4
Thick vermilion border 1 | 25
Thin hypoplastic alae nasi 1 | 51
Tortuous retinal vessels 1 | 15
biotin-responsive basal ganglia disease 1 | 8

Tissue

Endocrine System 17 | 18,159
Male tissues 17 | 17,142
Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Cardiovascular System 15 | 15,192

Target Family

Enzyme 12 | 4,145
Transporter 5 | 473

GO Function

hydrogen ion transmembrane tra... 17 | 17
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
V-type proton ATPase subunit B, kidney isoform ATP6V1B1 Tchem Enzyme -1.71459 43.7 251
Proton-coupled amino acid transporter 3 SLC36A3 Tdark Transporter -1.40039 22.5 31
ATP synthase F(0) complex subunit B1, mitochondrial ATP5PB Tbio Enzyme -0.79382 5.36 113
ATP synthase subunit g, mitochondrial ATP5MG Tdark Enzyme -0.27244 1.15 21
ATP synthase subunit g 2, mitochondrial ATP5MGL Tdark Enzyme 0.00000 82
Proton-coupled amino acid transporter 1 SLC36A1 Tbio Transporter -1.49042 31.8 68
ATP synthase subunit d, mitochondrial ATP5PD Tbio Enzyme -0.80693 5.27 179
ATP synthase subunit a MT-ATP6 Tbio Enzyme -2.74832 542.1 40
ATP synthase protein 8 MT-ATP8 Tbio Enzyme -2.35771 201.5 23
Proton-coupled folate transporter SLC46A1 Tchem Transporter -2.23182 177.1 76