Development Level

Tbio 11 | 10,625
Tdark 4 | 7,003
Tchem 3 | 1,890

IMPC Phenotype

preweaning lethality, complete... 3 | 633
decreased leukocyte cell numbe... 2 | 54
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
abnormal coat appearance 1 | 25
decreased circulating glucose ... 1 | 121
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased total body fat amoun... 1 | 186
increased fasted circulating g... 1 | 68
narrow eye opening 1 | 15
small adrenal glands 1 | 15
small lymph nodes 1 | 1

Disease

ovarian cancer 8 | 8,491
osteosarcoma 6 | 7,933
psoriasis 6 | 6,685
medulloblastoma, large-cell 5 | 6,234
Multiple myeloma 3 | 1,327
astrocytic glioma 3 | 2,241
lung cancer 3 | 4,473
malignant mesothelioma 3 | 3,163
oligodendroglioma 3 | 2,849
3-methylglutaconic aciduria 2 | 29
Anemia 2 | 252
IGA Glomerulonephritis 2 | 454
Leigh disease 2 | 81
Mitochondrial myopathy 2 | 24
Parkinson's disease 2 | 364
Pneumonia 2 | 133
Waldenstrons macroglobulinemia 2 | 764
atypical teratoid / rhabdoid tumor 2 | 4,369
glioblastoma 2 | 5,572
group 4 medulloblastoma 2 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
ulcerative colitis 2 | 2,087
Aceruloplasminemia 1 | 17
Acute lymphoid leukemia 1 | 25
Adenocarcinoma of lung (disorder) 1 | 48
Alcohol dependence 1 | 107
Anemia, Hypochromic Microcytic, With Iron Overload 1 | 1
Anemia, hypochromic microcytic, with iron overload 1 1 | 1
Body dysmorphic disorder 1 | 10
Burkitt's lymphoma 1 | 15
Carcinoma of female breast 1 | 20
Congenital defect of folate absorption 1 | 1
Degenerative polyarthritis 1 | 93
Diphyllobothriasis 1 | 6
Echinococcosis 1 | 28
Enamel erosion 1 | 15
Enlarged vestibular aqueduct 1 | 10
Fatal Familial Insomnia 1 | 6
Folate Malabsorption, Hereditary 1 | 1
Folic acid deficiency anemia 1 | 1
Gestational trophoblastic neoplasia 1 | 14
HYPERGLYCINURIA (disorder) 1 | 3
Hartnup disease 1 | 13
Heart Diseases 1 | 42
Hemochromatosis 1 | 55
Hereditary folate malabsorption 1 | 1
Hyperglycinuria 1 | 3
Hyperhomocysteinemia 1 | 34
Iminoglycinuria 1 | 4
Impaired glucose tolerance 1 | 12
Iron deficiency anemia 1 | 6
Juvenile rheumatoid arthritis 1 | 105
Lactic acidosis 1 | 43
Leber hereditary optic neuropathy 1 | 17
Leber's optic atrophy 1 | 10
Leigh syndrome 1 | 34
Liver carcinoma 1 | 217
Liver neoplasms 1 | 108
Major Depressive Disorder 1 | 106
Malabsorption Syndrome 1 | 1
Malignant hyperthermia 1 | 25
Malignant mesothelioma of pleura 1 | 7
Malignant tumor of head and/or neck 1 | 15
Malignant tumor of lung 1 | 5
Meningeal Leukemia 1 | 7
Mental depression 1 | 58
Metabolic acidosis 1 | 49
Mitochondrial complex V deficiency, mitochondrial 2 1 | 1
Mucopolysaccharidosis I 1 | 6
Mycosis fungoides 1 | 30
Nephrocalcinosis 1 | 18
Nephrolithiasis 1 | 31
Neuropathy 1 | 210
Non-Hodgkin's lymphoma 1 | 22
Optic Atrophy, Hereditary, Leber 1 | 14
Osteopetrosis 1 | 40
Osteoporosis 1 | 259
Osteosarcoma of bone 1 | 6
Ovarian Cysts 1 | 34
Pancytopenia 1 | 9
Pigmented villonodular synovitis 1 | 9
Renal tubular acidosis 1 | 14
Renal tubular acidosis, distal, with progressive nerve deafness 1 | 1
Retinitis pigmentosa 1 | 156
Sensorineural hearing loss 1 | 107
Stomach Neoplasms 1 | 282
Striatonigral Degeneration, Infantile 1 | 4
Toxic encephalopathy 1 | 131
adrenocortical carcinoma 1 | 1,427
astrocytoma 1 | 1,493
biotin-responsive basal ganglia disease 1 | 8
breast carcinoma 1 | 1,614
colon cancer 1 | 1,475
glioblastoma multiforme 1 | 347
glucocorticoid-induced osteoporosis 1 | 3
inflammatory breast cancer 1 | 404
medulloblastoma 1 | 1,524
pancreatic carcinoma 1 | 567
sarcoidosis 1 | 368
tuberculosis 1 | 1,563

Tissue

Blood and immune system 18 | 17,994
Cardiovascular System 18 | 17,957
Digestive Tract 18 | 18,472
Endocrine System 18 | 18,511
Female tissues 18 | 18,646
Liver and Pancreas 18 | 18,135
Nervous System 18 | 18,560
Respiratory system 18 | 17,483
Skin and soft tissues 18 | 18,114
Urinary Tract 18 | 18,443
Male tissues 17 | 17,968

Target Family

Enzyme 13 | 4,146
Transporter 5 | 473

GO Function

hydrogen ion transmembrane tra... 18 | 18
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine-threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP synthase subunit g 2, mitochondrial ATP5L2 Tdark Enzyme 0.00000 74
ATP synthase subunit a MT-ATP6 Tbio Enzyme -2.72887 525.9 36
ATP synthase subunit d, mitochondrial ATP5H Tbio Enzyme -0.73122 4.09 146
Proton-coupled amino acid transporter 1 SLC36A1 Tbio Transporter -1.46581 28.8 60
V-type proton ATPase subunit B, brain isoform ATP6V1B2 Tbio Enzyme -1.38406 23.2 119
ATP synthase subunit g, mitochondrial ATP5L Tdark Enzyme -0.27244 0.98 15
Natural resistance-associated macrophage protein 2 SLC11A2 Tchem Transporter -2.51831 352.2 235
ATP synthase protein 8 MT-ATP8 Tbio Enzyme -2.32809 191.4 20
V-type proton ATPase subunit F ATP6V1F Tbio Enzyme -0.91914 8.62 102
Proton-coupled folate transporter SLC46A1 Tchem Transporter -2.19727 163.1 71