Development Level

Tbio 84 | 11,445
Tdark 7 | 6,588
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

decreased vertical activity 4 | 208
prolonged QT interval 4 | 38
prolonged ST segment 4 | 36
preweaning lethality, complete... 3 | 979
decreased bone mineral content 2 | 151
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal locomotor behavior 1 | 24
abnormal ovary morphology 1 | 7
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
corneal opacity 1 | 32
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased lean body mass 1 | 135
decreased pulmonary respirator... 1 | 5
enlarged heart atrium 1 | 4
hyperactivity 1 | 148
increased blood uric acid leve... 1 | 5
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating triglyce... 1 | 42
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small testis 1 | 58

Disease

diabetes mellitus 39 | 1,728
Cancer 31 | 2,499
Obesity 31 | 678
psoriasis 31 | 6,694
Hypertension 29 | 396
Carcinoma 23 | 11,493
Kidney disease 21 | 430
Adenoma 20 | 167
ovarian cancer 20 | 8,520
pituitary cancer 20 | 1,972
osteosarcoma 19 | 7,950
Hypertensive disease 18 | 292
glioblastoma 18 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
lung cancer 18 | 4,740
Breast cancer 17 | 3,578
Heart disease 17 | 306
Hypoglycemia 17 | 152
Hypothyroidism 17 | 122
Polycystic ovary syndrome 17 | 360
medulloblastoma, large-cell 17 | 6,241
Coronary artery disease 16 | 268
Astrocytoma, Pilocytic 15 | 3,081
Diarrhea 15 | 253
Hyperglycemia 15 | 137
Hyperinsulinism 15 | 133
atypical teratoid / rhabdoid tumor 15 | 5,112
cystic fibrosis 15 | 1,696
ependymoma 15 | 4,679
adult high grade glioma 14 | 3,801
breast carcinoma 14 | 1,638
invasive ductal carcinoma 14 | 2,951
Acromegaly 13 | 51
Autosomal recessive predisposition 13 | 1,442
Constipation 13 | 181
Hyperthyroidism 13 | 53
Liver Cirrhosis, Experimental 13 | 769
Schizophrenia 13 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
malignant mesothelioma 13 | 3,232
Arthritis 12 | 290
Atherosclerosis 12 | 291
Cerebrovascular disease 12 | 238
Heart failure 12 | 162
Liver disease 12 | 237
ductal carcinoma in situ 12 | 1,745
oligodendroglioma 12 | 2,850
Amenorrhea 11 | 58
Anemia 11 | 365
Bipolar Disorder 11 | 666
Bradycardia 11 | 36
Hyperparathyroidism 11 | 48
Hypogonadism 11 | 173
Hypopituitarism 11 | 40
Hypotension 11 | 82
Infertility 11 | 188
Osteoporosis 11 | 363
group 4 medulloblastoma 11 | 1,855
lung carcinoma 11 | 2,843
Alzheimer's disease 10 | 658
Anorexia nervosa 10 | 80
Cushing's syndrome 10 | 48
Depressive disorder 10 | 409
Pancreatitis 10 | 123
Pituitary adenoma 10 | 38
astrocytic glioma 10 | 2,597
pancreatic cancer 10 | 2,398
Alcoholic Intoxication, Chronic 9 | 289
Autistic Disorder 9 | 364
Endometriosis 9 | 540
Hyperandrogenism 9 | 34
Inflammation 9 | 120
Mental Depression 9 | 333
Seizures 9 | 596
Weight decreased 9 | 103
colon cancer 9 | 1,478
fibroadenoma 9 | 559
group 3 medulloblastoma 9 | 4,104
primitive neuroectodermal tumor 9 | 3,035
Cardiomegaly 8 | 116
Cardiomyopathies 8 | 110
Diabetes Mellitus, Type 2 8 | 142
Down syndrome 8 | 499
Hyperprolactinemia 8 | 27
Major Depressive Disorder 8 | 301
Thyrotoxicosis 8 | 38
acute quadriplegic myopathy 8 | 1,158
ulcerative colitis 8 | 1,819
Diabetes Mellitus, Non-Insulin-Dependent 7 | 145
Epilepsy 7 | 792
Male infertility 7 | 206
Myocardial Ischemia 7 | 169
Pain agnosia 7 | 104
Prostatic Neoplasms 7 | 495
Tachycardia 7 | 43
adrenocortical carcinoma 7 | 1,428
interstitial cystitis 7 | 2,312
lung adenocarcinoma 7 | 2,716
primary pancreatic ductal adenocarcinoma 7 | 1,109

Tissue

Endocrine System 92 | 18,159
Digestive Tract 86 | 17,369
Female tissues 86 | 17,400
Liver and Pancreas 78 | 16,750
Skin and soft tissues 78 | 17,230
Blood and immune system 76 | 16,909
Respiratory system 73 | 16,393
Urinary Tract 71 | 16,678
Male tissues 69 | 17,142
Nervous System 66 | 16,725
Cardiovascular System 51 | 15,192

Target Family

Non-IDG 95 | 12,091
Enzyme 1 | 4,145

GO Function

hormone activity 96 | 96
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombopoietin THPO Tbio Non-IDG -3.23551 1632.3 440
Relaxin-3 RLN3 Tbio Non-IDG -1.88808 92.6 93
Urocortin-2 UCN2 Tbio Non-IDG -2.05990 129.7 107
Guanylin GUCA2A Tbio Non-IDG -1.92667 79.2 137
Insulin, isoform 2 INS-IGF2 Tbio Non-IDG -0.94621 7.72 72
Apelin receptor early endogenous ligand APELA Tbio Non-IDG 0.00000 0
Chorionic somatomammotropin hormone 2 CSH2 Tbio Non-IDG -2.95755 830.6 89
Stanniocalcin-2 STC2 Tbio Non-IDG -1.78204 65.8 317
Choriogonadotropin subunit beta 7 CGB7 Tdark Non-IDG -1.81507 82.5 0
Parathyroid hormone-related protein PTHLH Tbio Non-IDG -3.27676 2151.5 283