Development Level

Tbio 5 | 11,651
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
absent spleen 1 | 3
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged urinary bladder 1 | 8
hypoactivity 1 | 132
increased cardiac muscle contr... 1 | 8
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26

Disease

Carcinoma 4 | 11,493
Waldenstrons macroglobulinemia 4 | 765
lung cancer 4 | 4,740
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Cancer 3 | 2,499
acute quadriplegic myopathy 3 | 1,158
primary pancreatic ductal adenocarcinoma 3 | 1,109
Breast cancer 2 | 3,578
Multiple myeloma 2 | 1,332
Neurodegenerative disease 2 | 414
Prostatic Neoplasms 2 | 495
adult high grade glioma 2 | 3,801
dermatomyositis 2 | 966
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
psoriasis 2 | 6,694
Abnormal coordination 1 | 15
Abnormal visual pursuit 1 | 14
Adenocarcinoma of lung 1 | 142
Amyotrophic lateral sclerosis 1 | 451
Astrocytoma, Pilocytic 1 | 3,081
Ataxia, Appendicular 1 | 25
Atrophy of cerebellum 1 | 103
Atrophy of tongue 1 | 4
Autosomal dominant cerebellar ataxia 1 | 33
Babinski Reflex 1 | 100
Cerebellar Ataxia 1 | 304
Cerebellar degeneration 1 | 103
Congenital Pain Insensitivity 1 | 6
Disease Models, Animal 1 | 155
Disease Progression 1 | 136
Dysarthria 1 | 192
Fasciculation, Tongue 1 | 8
Gait Ataxia 1 | 51
HIV Infections 1 | 102
Hereditary sensory and autonomic neuropathy type 5 1 | 3
Hereditary sensory neuropathy 1 | 11
Hyperreflexia 1 | 209
Impaired smooth pursuit 1 | 14
Infratentorial atrophy 1 | 103
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE VIII 1 | 1
Neuropathy 1 | 261
Olivopontocerebellar atrophy 1 | 9
Pain Insensitivity, Congenital 1 | 2
Progressive disorder 1 | 142
Rheumatoid arthritis 1 | 1,191
Sensorineural hearing loss 1 | 106
Slowed saccades 1 | 12
Spinocerebellar Ataxias 1 | 34
Spinocerebellar ataxia 36 1 | 1
Spinocerebellar ataxia type 36 1 | 2
Stomach Neoplasms 1 | 300
Treacher Collins syndrome 1 | 27
Warsaw breakage syndrome 1 | 11
Wasting of tongue 1 | 4
active Crohn's disease 1 | 922
acute myeloid leukemia 1 | 783
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
atypical teratoid / rhabdoid tumor 1 | 5,112
colon cancer 1 | 1,478
diabetes mellitus 1 | 1,728
esophageal adenocarcinoma 1 | 737
gastric cancer 1 | 459
glioblastoma 1 | 5,792
interstitial cystitis 1 | 2,312
interstitial lung disease 1 | 298
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
invasive ductal carcinoma 1 | 2,951
nasopharyngeal carcinoma 1 | 1,058
pancreatic carcinoma 1 | 562
primitive neuroectodermal tumor 1 | 3,035
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Endocrine System 6 | 18,159
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Epigenetic 2 | 242
Non-IDG 2 | 12,091
TF/Epigenetic 2 | 38

GO Function

histone methyltransferase bind... 6 | 6
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chromobox protein homolog 3 CBX3 Tbio Epigenetic -2.00023 90.5 366
PR domain zinc finger protein 4 PRDM4 Tbio TF/Epigenetic -0.87918 7.84 221
Heat shock protein HSP 90-beta HSP90AB1 Tchem Non-IDG -2.04844 173.5 988
PR domain zinc finger protein 12 PRDM12 Tbio TF/Epigenetic -0.96029 10.5 105
Chromobox protein homolog 1 CBX1 Tbio Epigenetic -2.31837 203.1 260
Nucleolar protein 56 NOP56 Tbio Non-IDG -1.60255 40.7 73