Development Level

Tbio 83 | 11,445
Tchem 20 | 1,598
Tdark 7 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal behavior 4 | 298
decreased erythrocyte cell num... 4 | 62
preweaning lethality, incomple... 4 | 499
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
decreased body length 3 | 101
decreased body weight 3 | 161
decreased lymphocyte cell numb... 3 | 83
abnormal eye morphology 2 | 68
abnormal kidney morphology 2 | 65
abnormal neural tube closure 2 | 46
abnormal rib morphology 2 | 10
decreased circulating LDL chol... 2 | 38
decreased heart left ventricle... 2 | 28
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
edema 2 | 59
embryonic lethality prior to o... 2 | 239
increased bone mineral density 2 | 72
increased neutrophil cell numb... 2 | 46
increased total body fat amoun... 2 | 134
male infertility 2 | 123
prenatal lethality prior to he... 2 | 87
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal midbrain morphology 1 | 10
abnormal neural tube morpholog... 1 | 12
abnormal pelvic girdle bone mo... 1 | 12
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal tail morphology 1 | 25
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
corneal opacity 1 | 32
decreased basophil cell number 1 | 16
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased heart rate 1 | 18
decreased hematocrit 1 | 46
decreased kidney weight 1 | 1
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hydrometra 1 | 53
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased blood uric acid leve... 1 | 5
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating creatine... 1 | 5
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
narrow eye opening 1 | 12
polycystic kidney 1 | 15
prolonged RR interval 1 | 8
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56
thrombocytosis 1 | 27
tremors 1 | 39
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 81 | 11,493
ovarian cancer 66 | 8,520
osteosarcoma 57 | 7,950
medulloblastoma, large-cell 49 | 6,241
glioblastoma 45 | 5,792
psoriasis 40 | 6,694
atypical teratoid / rhabdoid tumor 39 | 5,112
group 3 medulloblastoma 39 | 4,104
lung cancer 38 | 4,740
Cancer 33 | 2,499
Breast cancer 30 | 3,578
primitive neuroectodermal tumor 28 | 3,035
malignant mesothelioma 26 | 3,232
Kidney cancer 25 | 2,613
ependymoma 25 | 4,679
adult high grade glioma 23 | 3,801
lung adenocarcinoma 21 | 2,716
oligodendroglioma 21 | 2,850
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
invasive ductal carcinoma 19 | 2,951
non-small cell lung cancer 19 | 2,890
tuberculosis 18 | 2,010
Pick disease 17 | 1,894
pancreatic cancer 17 | 2,398
subependymal giant cell astrocytoma 16 | 2,287
Multiple myeloma 15 | 1,332
acute myeloid leukemia 15 | 783
dermatomyositis 15 | 966
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
breast carcinoma 14 | 1,638
juvenile dermatomyositis 14 | 1,187
Intellectual disability 13 | 1,016
Rheumatoid arthritis 13 | 1,191
colon cancer 13 | 1,478
Waldenstrons macroglobulinemia 12 | 765
ductal carcinoma in situ 12 | 1,745
primary Sjogren syndrome 12 | 735
Atopic dermatitis 11 | 952
astrocytic glioma 11 | 2,597
astrocytoma 11 | 1,146
diabetes mellitus 11 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
progressive supranuclear palsy 11 | 676
ulcerative colitis 11 | 1,819
Astrocytoma, Pilocytic 10 | 3,081
pediatric high grade glioma 10 | 1,064
adrenocortical carcinoma 9 | 1,428
group 4 medulloblastoma 9 | 1,855
interstitial cystitis 9 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
cutaneous lupus erythematosus 8 | 1,057
hepatocellular carcinoma 8 | 547
lung carcinoma 8 | 2,843
Autistic Disorder 7 | 364
Endometriosis 7 | 540
acute quadriplegic myopathy 7 | 1,158
gastric cancer 7 | 459
nasopharyngeal carcinoma 7 | 1,058
pituitary cancer 7 | 1,972
primary pancreatic ductal adenocarcinoma 7 | 1,109
tuberculosis and treatment for 6 months 7 | 409
Alzheimer's disease 6 | 658
Disease Models, Animal 6 | 155
Multiple Sclerosis 6 | 540
active Crohn's disease 6 | 922
aldosterone-producing adenoma 6 | 665
cystic fibrosis 6 | 1,696
pancreatic carcinoma 6 | 562
sarcoidosis 6 | 370
Down syndrome 5 | 499
Epilepsy 5 | 792
Liver cancer 5 | 604
Schizophrenia 5 | 1,160
Systemic lupus erythematosus 5 | 194
hereditary spastic paraplegia 5 | 318
medulloblastoma 5 | 720
Adenoid Cystic Carcinoma 4 | 99
Anemia 4 | 365
Arthritis 4 | 290
Autism spectrum disorder 4 | 101
Breast Neoplasms 4 | 445
Carcinoma, Adenoid Cystic 4 | 99
Cognitive delay 4 | 608
Crohn's disease 4 | 321
Global developmental delay 4 | 608
Hypersensitivity reaction type II disease 4 | 253
Kidney disease 4 | 430
Mental and motor retardation 4 | 608
Neoplasm Metastasis 4 | 168
Obesity 4 | 678
Polycystic ovary syndrome 4 | 360
Thrombocytopenia 4 | 197
gastric carcinoma 4 | 807
inflammatory breast cancer 4 | 286
sonic hedgehog group medulloblastoma 4 | 467
spina bifida 4 | 1,074
Bipolar Disorder 3 | 666
Prostatic Neoplasms 3 | 495
Vascular disease 3 | 319
esophageal adenocarcinoma 3 | 737

Tissue

Endocrine System 107 | 18,159
Blood and immune system 106 | 16,909
Digestive Tract 106 | 17,369
Female tissues 106 | 17,400
Male tissues 106 | 17,142
Nervous System 106 | 16,725
Liver and Pancreas 105 | 16,750
Respiratory system 105 | 16,393
Skin and soft tissues 105 | 17,230
Urinary Tract 105 | 16,678
Cardiovascular System 104 | 15,192

Target Family

Non-IDG 56 | 12,091
Epigenetic 25 | 242
Enzyme 16 | 4,145
Transcription Factor 6 | 1,400
TF/Epigenetic 5 | 38
Kinase 3 | 634

GO Function

histone binding 111 | 111
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Importin-9 IPO9 Tbio Non-IDG -1.14983 12.2 108
FACT complex subunit SPT16 SUPT16H Tbio Enzyme -1.85453 70.7 324
Acidic leucine-rich nuclear phosphoprotein 32 family member E ANP32E Tbio Non-IDG -0.82034 5.60 97
E3 ubiquitin-protein ligase UHRF2 UHRF2 Tbio Epigenetic -1.57250 40.4 202
PHD finger protein 12 PHF12 Tbio Epigenetic -2.57717 385.3 70
Scm-like with four MBT domains protein 1 SFMBT1 Tbio Epigenetic -2.06810 112.0 113
Protein AF-9 MLLT3 Tbio Non-IDG -1.99555 93.8 210
Protein arginine N-methyltransferase 7 PRMT7 Tchem Epigenetic -1.32370 24.3 163
Transcription elongation factor SPT6 SUPT6H Tbio Non-IDG -1.80696 66.9 123
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Tchem TF/Epigenetic -2.07564 115.2 51