Development Level

Tbio 21 | 11,445
Tchem 6 | 1,598

IMPC Phenotype

abnormal embryo size 2 | 220
embryonic growth retardation 2 | 106
prenatal lethality prior to he... 2 | 87
preweaning lethality, complete... 2 | 979
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain development 1 | 20
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
absent seminal vesicle 1 | 4
anophthalmia 1 | 33
decreased body length 1 | 101
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hemorrhage 1 | 23
impaired righting response 1 | 26
increased circulating potassiu... 1 | 29
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small uterus 1 | 3

Disease

Carcinoma 20 | 11,493
ovarian cancer 19 | 8,520
Cancer 17 | 2,499
glioblastoma 17 | 5,792
medulloblastoma, large-cell 16 | 6,241
psoriasis 15 | 6,694
osteosarcoma 14 | 7,950
Breast cancer 11 | 3,578
ependymoma 10 | 4,679
group 3 medulloblastoma 10 | 4,104
lung cancer 10 | 4,740
atypical teratoid / rhabdoid tumor 9 | 5,112
primitive neuroectodermal tumor 9 | 3,035
Rheumatoid arthritis 8 | 1,191
diabetes mellitus 8 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung carcinoma 8 | 2,843
non-small cell lung cancer 8 | 2,890
oligodendroglioma 8 | 2,850
pancreatic cancer 8 | 2,398
ulcerative colitis 8 | 1,819
Astrocytoma, Pilocytic 7 | 3,081
adult high grade glioma 6 | 3,801
breast carcinoma 6 | 1,638
juvenile dermatomyositis 6 | 1,187
lung adenocarcinoma 6 | 2,716
tuberculosis 6 | 2,010
Multiple myeloma 5 | 1,332
Schizophrenia 5 | 1,160
adrenocortical carcinoma 5 | 1,428
astrocytic glioma 5 | 2,597
astrocytoma 5 | 1,146
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,109
Autosomal recessive predisposition 4 | 1,442
Brain Ischemia 4 | 110
Kidney cancer 4 | 2,613
Neurodegenerative disease 4 | 414
Prostatic Neoplasms 4 | 495
Short stature 4 | 531
Somatic mutation 4 | 61
Vascular disease 4 | 319
atypical teratoid/rhabdoid tumor 4 | 357
malignant mesothelioma 4 | 3,232
nasopharyngeal carcinoma 4 | 1,058
pediatric high grade glioma 4 | 1,064
primary Sjogren syndrome 4 | 735
subependymal giant cell astrocytoma 4 | 2,287
Amyotrophic lateral sclerosis 3 | 451
Arthritis, Rheumatoid 3 | 174
Asthma 3 | 385
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
Breast Neoplasms 3 | 445
Carcinoma, Hepatocellular 3 | 228
Cell Transformation, Neoplastic 3 | 97
Cryptorchidism 3 | 296
Endometriosis 3 | 540
Epilepsy 3 | 792
Ischemia 3 | 28
Kidney disease 3 | 430
Liver cancer 3 | 604
Liver carcinoma 3 | 240
Lung Neoplasms 3 | 232
Lung disease 3 | 142
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Mood Disorders 3 | 184
Neoplasm Invasiveness 3 | 161
Neoplasm Metastasis 3 | 168
Neoplastic Cell Transformation 3 | 89
Parkinson's disease 3 | 392
Skin Neoplasms 3 | 69
Stomach Neoplasms 3 | 300
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
colon cancer 3 | 1,478
dermatomyositis 3 | 966
gastric carcinoma 3 | 807
interstitial cystitis 3 | 2,312
mucosa-associated lymphoid tissue lymphoma 3 | 484
Allergic rhinitis 2 | 94
Atherosclerosis 2 | 291
Dermatitis 2 | 157
Heart disease 2 | 306
Hypersensitivity reaction type II disease 2 | 253
Hypertension 2 | 396
Inflammatory bowel disease 2 | 151
Multiple Sclerosis 2 | 540
Polycystic ovary syndrome 2 | 360
Psychotic Disorders 2 | 151
Reperfusion Injury 2 | 86
Seizures 2 | 596
Ventricular Septal Defects 2 | 119

Tissue

Blood and immune system 27 | 16,909
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678
Cardiovascular System 25 | 15,192

Target Family

Transcription Factor 14 | 1,400
Non-IDG 10 | 12,091
Enzyme 1 | 4,145
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GO Function

histone acetyltransferase bind... 27 | 27
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Metal regulatory transcription factor 1 MTF1 Tbio Transcription Factor -1.98140 101.0 135
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
Myocardin MYOCD Tbio Non-IDG -2.37801 242.7 84
Transcription initiation factor TFIID subunit 7 TAF7 Tbio Non-IDG -1.16026 13.4 138
Protein C-ets-1 ETS1 Tbio Transcription Factor -2.89500 760.0 463
E3 ubiquitin-protein ligase TRIM68 TRIM68 Tbio Enzyme -0.55159 4.50 126
Nuclear receptor subfamily 4 group A member 3 NR4A3 Tbio Nuclear Receptor -2.02752 112.7 289
Breast carcinoma-amplified sequence 3 BCAS3 Tbio Non-IDG -1.24719 16.2 149
Zinc finger and BTB domain-containing protein 7A ZBTB7A Tbio Transcription Factor -2.18148 152.0 284