Development Level

Tbio 118 | 11,445
Tchem 30 | 1,598
Tclin 9 | 613
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 7 | 499
preweaning lethality, complete... 6 | 979
abnormal bone structure 4 | 187
abnormal embryo size 3 | 220
abnormal retinal vasculature m... 3 | 27
decreased vertical activity 3 | 208
enlarged heart 3 | 210
abnormal behavioral response t... 2 | 66
abnormal heart morphology 2 | 162
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased erythrocyte cell num... 2 | 62
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
impaired pupillary reflex 2 | 26
impaired righting response 2 | 26
increased circulating bilirubi... 2 | 16
increased circulating choleste... 2 | 66
increased mean corpuscular hem... 2 | 36
increased total body fat amoun... 2 | 134
abnormal body wall morphology 1 | 9
abnormal cornea morphology 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal heart left ventricle ... 1 | 16
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal outer nuclear... 1 | 3
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
cleft palate 1 | 8
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased spleen weight 1 | 10
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
female infertility 1 | 60
fused cornea and lens 1 | 5
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased startle reflex 1 | 112
iris synechia 1 | 3
limb grasping 1 | 41
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small testis 1 | 58
tremors 1 | 39

Disease

Carcinoma 98 | 11,493
ovarian cancer 85 | 8,520
psoriasis 79 | 6,694
Cancer 65 | 2,499
osteosarcoma 65 | 7,950
glioblastoma 64 | 5,792
Breast cancer 62 | 3,578
lung cancer 62 | 4,740
invasive ductal carcinoma 60 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 59 | 2,955
malignant mesothelioma 57 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 56 | 2,989
medulloblastoma, large-cell 56 | 6,241
lung adenocarcinoma 55 | 2,716
lung carcinoma 54 | 2,843
cystic fibrosis 51 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 51 | 3,291
non-small cell lung cancer 51 | 2,890
atypical teratoid / rhabdoid tumor 49 | 5,112
ependymoma 49 | 4,679
interstitial cystitis 47 | 2,312
adult high grade glioma 46 | 3,801
pancreatic cancer 46 | 2,398
Astrocytoma, Pilocytic 44 | 3,081
diabetes mellitus 39 | 1,728
group 3 medulloblastoma 38 | 4,104
breast carcinoma 37 | 1,638
ulcerative colitis 37 | 1,819
pituitary cancer 36 | 1,972
oligodendroglioma 34 | 2,850
ductal carcinoma in situ 33 | 1,745
Kidney cancer 32 | 2,613
astrocytic glioma 28 | 2,597
colon cancer 28 | 1,478
primary pancreatic ductal adenocarcinoma 27 | 1,109
Atopic dermatitis 26 | 952
adrenocortical carcinoma 26 | 1,428
primitive neuroectodermal tumor 26 | 3,035
Atherosclerosis 25 | 291
cutaneous lupus erythematosus 25 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
nasopharyngeal carcinoma 24 | 1,058
Autosomal recessive predisposition 23 | 1,442
Schizophrenia 22 | 1,160
Hypertension 21 | 396
Kidney disease 21 | 430
autosomal dominant Emery-Dreifuss muscular dystrophy 21 | 510
gastric carcinoma 21 | 807
juvenile dermatomyositis 21 | 1,187
fibroadenoma 20 | 559
Coronary artery disease 19 | 268
Pick disease 19 | 1,894
tuberculosis 19 | 2,010
Vascular disease 18 | 319
subependymal giant cell astrocytoma 18 | 2,287
Alzheimer's disease 17 | 658
Duchenne muscular dystrophy 17 | 601
Liver Cirrhosis, Experimental 17 | 769
limb girdle muscular dystrophy 2A 16 | 213
Arthritis 15 | 290
Cerebrovascular disease 15 | 238
Endometriosis 15 | 540
Heart disease 15 | 306
Hypertensive disease 15 | 292
Rheumatoid arthritis 15 | 1,191
group 4 medulloblastoma 15 | 1,855
Lung disease 14 | 142
non primary Sjogren syndrome sicca 14 | 891
Breast Neoplasms 13 | 445
Down syndrome 13 | 499
Liver Cirrhosis 13 | 181
Mammary Neoplasms 13 | 425
active ulcerative colitis 13 | 764
acute quadriplegic myopathy 13 | 1,158
Obesity 12 | 678
esophageal adenocarcinoma 12 | 737
mucosa-associated lymphoid tissue lymphoma 12 | 484
Asthma 11 | 385
Becker muscular dystrophy 11 | 191
Cleft Palate 11 | 271
Melanoma 11 | 711
Multiple myeloma 11 | 1,332
Osteoporosis 11 | 363
Seizures 11 | 596
astrocytoma 11 | 1,146
medulloblastoma 11 | 720
Cleft Lip 10 | 141
Depressive disorder 10 | 409
Glaucoma 10 | 239
Multiple Sclerosis 10 | 540
Orbital separation excessive 10 | 244
Skin cancer 10 | 469
Waldenstrons macroglobulinemia 10 | 765
interstitial lung disease 10 | 298
pediatric high grade glioma 10 | 1,064
Arthritis, Rheumatoid 9 | 174
Cognitive delay 9 | 608
Mental and motor retardation 9 | 608
gastric cancer 9 | 459
spina bifida 9 | 1,074

Tissue

Endocrine System 158 | 18,159
Digestive Tract 156 | 17,369
Liver and Pancreas 156 | 16,750
Skin and soft tissues 156 | 17,230
Female tissues 155 | 17,400
Male tissues 153 | 17,142
Urinary Tract 153 | 16,678
Blood and immune system 152 | 16,909
Respiratory system 149 | 16,393
Nervous System 145 | 16,725
Cardiovascular System 132 | 15,192

Target Family

Non-IDG 118 | 12,091
Enzyme 36 | 4,145
Kinase 3 | 634
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408

GO Function

heparin binding 161 | 161
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
R-spondin-4 RSPO4 Tbio Non-IDG -1.45244 28.7 66
Teneurin-1 TENM1 Tbio Non-IDG -1.81805 61.8 60
Transmembrane glycoprotein NMB GPNMB Tbio Non-IDG -2.05817 130.8 293
Latexin LXN Tbio Enzyme -2.54426 344.4 419
Latent-transforming growth factor beta-binding protein 2 LTBP2 Tbio Non-IDG -1.22721 18.2 100
Megakaryocyte and platelet inhibitory receptor G6b MPIG6B Tbio Non-IDG -1.00429 11.8 53
Reticulon-4 receptor-like 1 RTN4RL1 Tbio Non-IDG -0.81334 6.43 92
A disintegrin and metalloproteinase with thrombospondin motifs 1 ADAMTS1 Tchem Enzyme -2.44459 279.8 227
Follistatin-related protein 1 FSTL1 Tbio Non-IDG -1.98038 117.5 265