Development Level

Tbio 17 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
decreased exploration in new e... 2 | 11
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal limb bud morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
decreased circulating bilirubi... 1 | 19
decreased heart rate variabili... 1 | 13
decreased leukocyte cell numbe... 1 | 73
edema 1 | 59
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
pallor 1 | 34
premature death 1 | 5
small adrenal glands 1 | 16
small kidney 1 | 16
tremors 1 | 39

Disease

Carcinoma 17 | 11,493
psoriasis 16 | 6,694
glioblastoma 11 | 5,792
ovarian cancer 11 | 8,520
medulloblastoma, large-cell 10 | 6,241
osteosarcoma 10 | 7,950
Breast cancer 9 | 3,578
atypical teratoid / rhabdoid tumor 9 | 5,112
lung carcinoma 9 | 2,843
Astrocytoma, Pilocytic 7 | 3,081
Kidney cancer 7 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
invasive ductal carcinoma 7 | 2,951
lung cancer 7 | 4,740
non-small cell lung cancer 7 | 2,890
primitive neuroectodermal tumor 7 | 3,035
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
pituitary cancer 6 | 1,972
Cancer 5 | 2,499
Congenital Epicanthus 5 | 177
Simpson-Golabi-Behmel syndrome 5 | 19
cystic fibrosis 5 | 1,696
ductal carcinoma in situ 5 | 1,745
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
oligodendroglioma 5 | 2,850
Acquired scoliosis 4 | 281
Broad flat nasal bridge 4 | 236
Curvature of spine 4 | 282
Melanoma 4 | 711
Nasal bridge wide 4 | 236
Orbital separation excessive 4 | 244
Parkinson's disease 4 | 392
Short neck 4 | 140
breast carcinoma 4 | 1,638
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
juvenile dermatomyositis 4 | 1,187
pediatric high grade glioma 4 | 1,064
Atopic dermatitis 3 | 952
Atrial Septal Defects 3 | 85
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Cleft Palate 3 | 271
Concave bridge of nose 3 | 195
Cryptorchidism 3 | 296
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Depressive disorder 3 | 409
Downward slant of palpebral fissure 3 | 158
Hypoplastic feet 3 | 66
Low-set, posteriorly rotated ears 3 | 110
Mental Depression 3 | 333
Multiple Sclerosis 3 | 540
Muscle hypotonia 3 | 571
Pick disease 3 | 1,894
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Short distal phalanges 3 | 50
Short hands 3 | 50
Short nose 3 | 132
Skin cancer 3 | 469
Small nose 3 | 132
Splenomegaly 3 | 190
Thrombocytopenia 3 | 197
Umbilical hernia 3 | 93
Vascular disease 3 | 319
Ventricular Septal Defects 3 | 119
astrocytic glioma 3 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
fibroadenoma 3 | 559
group 4 medulloblastoma 3 | 1,855
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109
sonic hedgehog group medulloblastoma 3 | 467
ulcerative colitis 3 | 1,819
Breast Neoplasms 2 | 445
Cardiac Arrhythmia 2 | 103
Cardiac conduction abnormalities 2 | 78
Cardiomyopathies 2 | 110
Class III malocclusion 2 | 78
Conduction disorder of the heart 2 | 79
Congenital deafness 2 | 185
Craniofacial Abnormalities 2 | 151
Deafness 2 | 198
EKG abnormalities 2 | 78
Electrocardiogram abnormal 2 | 81
Electrocardiogram change 2 | 78
Hearing Loss, Partial 2 | 185
Increased size of mandible 2 | 78
Mammary Neoplasms 2 | 425
Mandibular hyperplasia 2 | 78
Nail dysplasia 2 | 52
Somatic mutation 2 | 61
hearing impairment 2 | 199
mandibular excess (physical finding) 2 | 78

Tissue

Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Blood and immune system 20 | 16,909
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Cardiovascular System 16 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 4 | 4,145
Transporter 1 | 473

GO Function

heparan sulfate proteoglycan b... 21 | 21
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glypican-6 GPC6 Tbio Non-IDG -1.33560 21.9 125
Semaphorin-5A SEMA5A Tbio Non-IDG -1.82162 69.8 238
Sodium/potassium-transporting ATPase subunit alpha-3 ATP1A3 Tclin Transporter -2.24223 170.0 132
Fibroblast growth factor 20 FGF20 Tbio Non-IDG -1.71980 55.3 117
Cartilage oligomeric matrix protein COMP Tbio Non-IDG -2.77423 538.3 259
Follistatin FST Tbio Non-IDG -3.07812 1179.4 356
Glypican-2 GPC2 Tbio Non-IDG -1.10212 12.9 106
Glypican-5 GPC5 Tbio Non-IDG -1.65766 45.7 200
Inactive heparanase-2 HPSE2 Tbio Enzyme -2.52081 326.4 137
Group IID secretory phospholipase A2 PLA2G2D Tchem Enzyme -2.16892 139.3 119