Development Level

Tbio 60 | 10,625
Tchem 38 | 1,890
Tclin 19 | 602
Tdark 10 | 7,003

IMPC Term

decreased total body fat amoun... 5 | 186
abnormal behavior 3 | 226
abnormal bone structure 3 | 131
decreased bone mineral content 3 | 157
increased bone mineral content 3 | 92
preweaning lethality, incomple... 3 | 260
abnormal femur morphology 2 | 14
abnormal lens morphology 2 | 73
decreased blood urea nitrogen ... 2 | 31
decreased bone mineral density 2 | 126
decreased circulating alkaline... 2 | 41
decreased circulating choleste... 2 | 85
decreased circulating insulin ... 2 | 75
decreased circulating triglyce... 2 | 83
decreased lean body mass 2 | 195
decreased mean platelet volume 2 | 12
decreased vertical activity 2 | 22
improved glucose tolerance 2 | 56
increased circulating alkaline... 2 | 119
increased fasted circulating g... 2 | 68
small kidney 2 | 10
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal clavicle morphology 1 | 5
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal cranium morphology 1 | 32
abnormal eye morphology 1 | 38
abnormal eye posterior chamber... 1 | 3
abnormal fibula morphology 1 | 2
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 14
abnormal pelvic girdle bone mo... 1 | 11
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 28
abnormal scapula morphology 1 | 3
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
absent mammary gland 1 | 1
absent vibrissae 1 | 14
cataract 1 | 26
decreased NK cell number 1 | 16
decreased body length 1 | 108
decreased cardiac output 1 | 2
decreased caudal vertebrae num... 1 | 49
decreased cervical vertebrae n... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating amylase ... 1 | 24
decreased circulating calcium ... 1 | 33
decreased circulating glucose ... 1 | 121
decreased circulating phosphat... 1 | 15
decreased grip strength 1 | 123
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased leukocyte cell numbe... 1 | 54
decreased skeletal muscle mass 1 | 1
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased circulating HDL chol... 1 | 63
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased respiratory quotient 1 | 12
increased spleen weight 1 | 3
increased total body fat amoun... 1 | 57
persistence of hyaloid vascula... 1 | 22
preweaning lethality, complete... 1 | 633
short tibia 1 | 82
shortened QRS complex duration 1 | 1
small heart 1 | 8
small ovary 1 | 1
small spleen 1 | 11
small uterus 1 | 1
stereotypic behavior 1 | 3
thin skin 1 | 1
thin ventricular wall 1 | 5
trunk curl 1 | 15

Disease

psoriasis 61 | 6,685
osteosarcoma 48 | 7,933
ovarian cancer 48 | 8,484
Cancer 39 | 2,346
lung cancer 37 | 4,466
glioblastoma 34 | 5,572
medulloblastoma, large-cell 33 | 6,234
interstitial cystitis 31 | 2,299
lung carcinoma 31 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,289
lung adenocarcinoma 27 | 2,713
non-small cell lung cancer 27 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,956
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
diabetes mellitus 23 | 1,663
invasive ductal carcinoma 23 | 2,950
pancreatic cancer 23 | 2,300
ulcerative colitis 23 | 2,087
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,988
pilocytic astrocytoma 22 | 3,086
Hypertension 21 | 287
pediatric high grade glioma 21 | 2,712
Prostatic Neoplasms 20 | 471
atypical teratoid / rhabdoid tumor 20 | 4,369
oligodendroglioma 20 | 2,849
tuberculosis 20 | 1,557
Breast cancer 19 | 3,094
Kidney disease 19 | 396
primitive neuroectodermal tumor 19 | 3,031
malignant mesothelioma 18 | 3,162
Mammary Neoplasms 17 | 410
adrenocortical carcinoma 16 | 1,427
posterior fossa group A ependymoma 16 | 1,511
breast carcinoma 15 | 1,614
cystic fibrosis 15 | 1,665
ductal carcinoma in situ 15 | 1,745
group 3 medulloblastoma 15 | 2,254
pituitary cancer 14 | 1,972
Atherosclerosis 13 | 275
adult high grade glioma 13 | 2,148
group 4 medulloblastoma 13 | 1,875
Carcinoma 12 | 2,147
Liver disease 12 | 219
cutaneous lupus erythematosus 12 | 1,056
ependymoma 12 | 2,514
gastric carcinoma 12 | 832
Anemia 11 | 252
Atopic dermatitis 11 | 944
Pick disease 11 | 1,893
astrocytic glioma 11 | 2,241
astrocytoma 11 | 1,493
atypical teratoid/rhabdoid tumor 11 | 1,095
primary pancreatic ductal adenocarcinoma 11 | 1,271
Alzheimer's disease 10 | 644
Cerebrovascular disease 10 | 231
Endometriosis 10 | 535
Lung Neoplasms 10 | 171
Malaria 10 | 140
Obesity 10 | 616
Rheumatoid Arthritis 10 | 1,160
Thalassemia 10 | 46
active Crohn's disease 10 | 918
aldosterone-producing adenoma 10 | 664
chronic rhinosinusitis 10 | 512
subependymal giant cell astrocytoma 10 | 2,287
Acute kidney injury 9 | 65
Coronary artery disease 9 | 240
Diabetes Mellitus, Experimental 9 | 106
Drug-Induced Liver Injury 9 | 118
Heart disease 9 | 279
Hypertensive disease 9 | 193
Kidney Failure, Chronic 9 | 45
Vascular disease 9 | 281
medulloblastoma 9 | 1,524
posterior fossa group B ependymoma 9 | 1,530
Asthma 8 | 349
Heart failure 8 | 80
Peripheral Neuropathy 8 | 303
Reperfusion Injury 8 | 84
Schizophrenia 8 | 501
esophageal adenocarcinoma 8 | 737
pancreatic carcinoma 8 | 567
primary Sjogren syndrome 8 | 789
sonic hedgehog group medulloblastoma 8 | 1,482
Adenocarcinoma 7 | 115
Arthritis 7 | 248
Brain Ischemia 7 | 87
Congenital adrenal hyperplasia 7 | 74
Hemolytic anemia 7 | 66
Liver Cirrhosis, Experimental 7 | 108
Parkinson's disease 7 | 364
Polycystic Ovary Syndrome 7 | 332
Toxic encephalopathy 7 | 131
colon cancer 7 | 1,475
nasopharyngeal carcinoma 7 | 1,056
periodontitis 7 | 269
acute myeloid leukemia 6 | 780
acute quadriplegic myopathy 6 | 1,157
juvenile dermatomyositis 6 | 1,189
mucosa-associated lymphoid tissue lymphoma 6 | 480

Tissue

Endocrine System 124 | 18,512
Female tissues 124 | 18,647
Digestive Tract 123 | 18,473
Nervous System 123 | 18,561
Skin and soft tissues 123 | 18,115
Urinary Tract 123 | 18,444
Blood and immune system 122 | 17,995
Cardiovascular System 122 | 17,958
Liver and Pancreas 122 | 18,136
Male tissues 121 | 17,969
Respiratory system 121 | 17,484

Target Family

Non-IDG 64 | 11,971
Enzyme 56 | 4,146
Kinase 3 | 634
Ion Channel 1 | 341
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Function

heme binding 127 | 127
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Indoleamine 2,3-dioxygenase 2 IDO2 Tchem Enzyme -1.88853 82.2 208
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.56294 358.8 154
24-hydroxycholesterol 7-alpha-hydroxylase CYP39A1 Tbio Enzyme -0.95411 6.43 97
Cytochrome b5 CYB5A Tchem Non-IDG -3.24788 1711.2 249
Microprocessor complex subunit DGCR8 DGCR8 Tbio Non-IDG -2.41582 254.1 201
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.20847 1594.9 391
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.32560 2206.3 649
Cytochrome P450 4V2 CYP4V2 Tbio Non-IDG -2.66290 481.8 87
Lactoperoxidase LPO Tbio Enzyme -2.69742 442.5 160
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.03668 12041.6 648