Development Level

Tbio 34 | 11,445
Tchem 11 | 1,598
Tdark 5 | 6,588
Tclin 4 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
decreased total body fat amoun... 4 | 207
increased lean body mass 4 | 172
preweaning lethality, complete... 4 | 979
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
corneal opacity 1 | 32
decreased anxiety-related resp... 1 | 12
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating sodium l... 1 | 71
increased mean platelet volume 1 | 45
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 33 | 11,493
ovarian cancer 30 | 8,520
lung cancer 22 | 4,740
medulloblastoma, large-cell 22 | 6,241
Cancer 20 | 2,499
osteosarcoma 20 | 7,950
glioblastoma 19 | 5,792
psoriasis 19 | 6,694
atypical teratoid / rhabdoid tumor 16 | 5,112
group 3 medulloblastoma 16 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
ependymoma 14 | 4,679
Rheumatoid arthritis 12 | 1,191
pancreatic cancer 11 | 2,398
adult high grade glioma 10 | 3,801
astrocytoma 10 | 1,146
interstitial cystitis 10 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
invasive ductal carcinoma 9 | 2,951
lung adenocarcinoma 9 | 2,716
oligodendroglioma 9 | 2,850
primitive neuroectodermal tumor 9 | 3,035
astrocytic glioma 8 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
malignant mesothelioma 8 | 3,232
non-small cell lung cancer 8 | 2,890
Astrocytoma, Pilocytic 7 | 3,081
Breast cancer 7 | 3,578
diabetes mellitus 7 | 1,728
lung carcinoma 7 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
subependymal giant cell astrocytoma 7 | 2,287
Intellectual disability 6 | 1,016
Kidney cancer 6 | 2,613
Multiple myeloma 6 | 1,332
Parkinson's disease 6 | 392
dermatomyositis 6 | 966
Major Depressive Disorder 5 | 301
Pick disease 5 | 1,894
Schizophrenia 5 | 1,160
Unipolar Depression 5 | 250
acute myeloid leukemia 5 | 783
acute quadriplegic myopathy 5 | 1,158
adrenocortical carcinoma 5 | 1,428
colon cancer 5 | 1,478
group 4 medulloblastoma 5 | 1,855
pancreatic carcinoma 5 | 562
tuberculosis 5 | 2,010
Alzheimer's disease 4 | 658
Arthritis 4 | 290
Asthma 4 | 385
Atherosclerosis 4 | 291
Autosomal recessive predisposition 4 | 1,442
Depressive disorder 4 | 409
Epilepsy 4 | 792
Kidney disease 4 | 430
Mental Depression 4 | 333
Muscle hypotonia 4 | 571
Vascular disease 4 | 319
Waldenstrons macroglobulinemia 4 | 765
breast carcinoma 4 | 1,638
gastric cancer 4 | 459
hepatocellular carcinoma 4 | 547
non primary Sjogren syndrome sicca 4 | 891
Amyotrophic lateral sclerosis 3 | 451
Autistic Disorder 3 | 364
Bipolar Disorder 3 | 666
Coronary artery disease 3 | 268
Dermatitis 3 | 157
Duchenne muscular dystrophy 3 | 601
Dull intelligence 3 | 645
Endometriosis 3 | 540
HIV Infections 3 | 102
Huntington's disease 3 | 76
Hyperreflexia 3 | 209
Liver Cirrhosis, Experimental 3 | 769
Long philtrum 3 | 137
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Mood Disorders 3 | 184
Muscle Weakness 3 | 170
Nerve Degeneration 3 | 121
Neuropathy 3 | 261
Obesity 3 | 678
Poor school performance 3 | 645
Prevention of Cardiac Transplant Rejection 3 | 15
Prevention of Liver Transplant Rejection 3 | 15
Renal Cell Carcinoma 3 | 214
Seizures 3 | 596
Short stature 3 | 531
Small head 3 | 374
aldosterone-producing adenoma 3 | 665
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,057
inflammatory breast cancer 3 | 286
nasopharyngeal carcinoma 3 | 1,058
pediatric high grade glioma 3 | 1,064
posterior fossa group B ependymoma 3 | 416
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Endocrine System 54 | 18,159
Female tissues 54 | 17,400
Male tissues 54 | 17,142
Respiratory system 54 | 16,393
Skin and soft tissues 54 | 17,230
Blood and immune system 53 | 16,909
Digestive Tract 53 | 17,369
Liver and Pancreas 53 | 16,750
Nervous System 53 | 16,725
Urinary Tract 53 | 16,678
Cardiovascular System 51 | 15,192

Target Family

Non-IDG 30 | 12,091
Enzyme 15 | 4,145
Kinase 3 | 634
GPCR 2 | 408
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
Ion Channel 1 | 344

GO Function

heat shock protein binding 54 | 54
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
FAS-associated factor 1 FAF1 Tbio Non-IDG -1.71858 56.5 209
DnaJ homolog subfamily A member 4 DNAJA4 Tbio Non-IDG -0.52235 2.67 120
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Methyltransferase-like protein 23 METTL23 Tdark Enzyme -0.17609 1.92 6
Peptidyl-prolyl cis-trans isomerase FKBP5 FKBP5 Tchem Enzyme -2.52114 348.1 299
Myotonin-protein kinase DMPK Tchem Kinase -2.70945 496.6 196
Integrin alpha-M ITGAM Tbio Non-IDG -3.63427 3939.5 2165
DnaJ homolog subfamily C member 9 DNAJC9 Tbio Non-IDG -0.73182 5.58 94
Heat shock 70 kDa protein 1B HSPA1B Tbio Non-IDG -1.61862 0.00000 60
Nucleoprotein TPR TPR Tbio Non-IDG -2.11491 135.6 161