Development Level

Tclin 6 | 602
Tbio 2 | 10,625
Tchem 1 | 1,890

Disease

Carcinoma 5 | 2,147
Decompensated cardiac failure 5 | 9
lung cancer 5 | 4,466
Angina Pectoris Prevention 4 | 4
Angina pectoris 4 | 21
Chronic heart failure 4 | 46
Controlled Hypotension 4 | 6
Hypertensive disorder 4 | 58
Hypertensive urgency 4 | 10
Left ventricular cardiac dysfunction 4 | 9
Malignant essential hypertension 4 | 5
Perioperative hypertension 4 | 5
Persistent pulmonary hypertension of the newborn 4 | 8
Pulmonary hypertension 4 | 52
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
ovarian cancer 4 | 8,484
Pick disease 3 | 1,893
adult high grade glioma 3 | 2,148
atypical teratoid / rhabdoid tumor 3 | 4,369
breast carcinoma 3 | 1,614
gastric carcinoma 3 | 832
glioblastoma 3 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
lung adenocarcinoma 3 | 2,713
lung carcinoma 3 | 2,844
medulloblastoma, large-cell 3 | 6,234
non-small cell lung cancer 3 | 2,798
osteosarcoma 3 | 7,933
posterior fossa group B ependymoma 3 | 1,530
ulcerative colitis 3 | 2,087
Breast cancer 2 | 3,094
Clostridium difficile colitis 2 | 12
Colorectal Neoplasms 2 | 217
Cone dystrophy 2 | 57
Hypertension 2 | 287
Hypertensive disease 2 | 193
Leber congenital amaurosis 2 | 72
acute myeloid leukemia 2 | 780
colon cancer 2 | 1,475
ductal carcinoma in situ 2 | 1,745
interstitial cystitis 2 | 2,299
invasive ductal carcinoma 2 | 2,950
malignant mesothelioma 2 | 3,162
non primary Sjogren syndrome sicca 2 | 840
pancreatic cancer 2 | 2,300
pancreatic carcinoma 2 | 567
pilocytic astrocytoma 2 | 3,086
primitive neuroectodermal tumor 2 | 3,031
psoriasis 2 | 6,685
tuberculosis 2 | 1,557
Achalasia 1 | 11
Acromesomelic dysplasia 1 | 10
Adenoid Cystic Carcinoma 1 | 99
Amaurosis congenita of Leber, type 1 1 | 1
Blindness 1 | 84
Blood pressure finding 1 | 56
Bradyopsia 1 | 10
Cardiomegaly 1 | 66
Central areolar choroidal sclerosis 1 | 2
Chronic idiopathic constipation 1 | 3
Chronic thromboembolic pulmonary hypertension 1 | 4
Colonic Neoplasms 1 | 126
Colorectal Cancer 1 | 47
Cone-Rod Dystrophy 5 1 | 2
Congestive heart failure 1 | 30
Constipation 1 | 43
Coronary artery disease 1 | 240
Diarrhea 1 | 155
Essential Hypertension 1 | 82
Fibrosis 1 | 40
Fundus dystrophy 1 | 77
Heart failure 1 | 80
Irritable bowel syndrome 1 | 59
Irritable bowel syndrome characterized by constipation 1 | 3
Kabuki syndrome 1 | 27
Kidney Diseases 1 | 86
Mammary Neoplasms 1 | 410
Mammographic Density 1 | 8
Parkinson's disease 1 | 364
Partial central choroid dystrophy 1 | 12
Pyloric stenosis 1 | 9
Retinal Degeneration 1 | 49
Retinal cone dystrophy 2 1 | 1
Retinitis pigmentosa 1 | 153
Salivary Gland Neoplasms 1 | 45
Systemic arterial pressure 1 | 56
astrocytic glioma 1 | 2,241
astrocytoma 1 | 1,493
cone-rod dystrophy 1 | 56
fibroadenoma 1 | 557
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,289
medulloblastoma 1 | 1,524
oligodendroglioma 1 | 2,849
pediatric high grade glioma 1 | 2,712
primary pancreatic ductal adenocarcinoma 1 | 1,271
progressive supranuclear palsy 1 | 674
pulmonary arterial hypertension 1 | 36
sarcoidosis 1 | 358
sonic hedgehog group medulloblastoma 1 | 1,482
spina bifida 1 | 1,064

Tissue

Blood and immune system 8 | 17,995
Cardiovascular System 8 | 17,958
Digestive Tract 8 | 18,473
Endocrine System 8 | 18,512
Female tissues 8 | 18,647
Liver and Pancreas 8 | 18,136
Male tissues 8 | 17,969
Nervous System 8 | 18,561
Respiratory system 8 | 17,484
Skin and soft tissues 8 | 18,115
Urinary Tract 8 | 18,444

Target Family

Kinase 5 | 634
Enzyme 4 | 4,146

GO Function

guanylate cyclase activity 9 | 9
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Retinal guanylyl cyclase 2 GUCY2F Tbio Kinase -1.03655 7.37 72
Retinal guanylyl cyclase 1 GUCY2D Tbio Kinase -2.21858 178.4 196
Heat-stable enterotoxin receptor GUCY2C Tclin Kinase -2.28326 196.5 217
Guanylate cyclase soluble subunit alpha-2 GUCY1A2 Tclin Enzyme -1.38714 23.4 87
Guanylate cyclase soluble subunit beta-2 GUCY1B2 Tclin Enzyme 0.00000 0
Atrial natriuretic peptide receptor 2 NPR2 Tchem Kinase -2.08865 135.1 159
Guanylate cyclase soluble subunit alpha-3 GUCY1A3 Tclin Enzyme -1.57897 36.7 140
Guanylate cyclase soluble subunit beta-1 GUCY1B3 Tclin Enzyme -1.48068 28.6 191
Atrial natriuretic peptide receptor 1 NPR1 Tclin Kinase -2.58111 394.8 177