Development Level

Tclin 3 | 613
Tbio 2 | 11,445

Disease

Carcinoma 5 | 11,493
Cancer 4 | 2,499
ovarian cancer 4 | 8,520
Immune system cancer 3 | 140
Kidney cancer 3 | 2,613
Liver Cirrhosis, Experimental 3 | 769
Lymphoid leukemia 3 | 160
Polycythemia vera 3 | 27
Rheumatoid arthritis 3 | 1,191
ependymoma 3 | 4,679
lung cancer 3 | 4,740
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
psoriasis 3 | 6,694
Anemia 2 | 365
Arthralgia 2 | 90
Autosomal recessive predisposition 2 | 1,442
Crohn's disease 2 | 321
Myelofibrosis 2 | 14
Myeloproliferative disorder 2 | 2
Obesity 2 | 678
Polycythemia 2 | 25
Systemic lupus erythematosus 2 | 194
Thrombocytopenia 2 | 197
atypical teratoid / rhabdoid tumor 2 | 5,112
cystic fibrosis 2 | 1,696
glioblastoma 2 | 5,792
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Acute blood cancer 1 | 6
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Anti-nuclear factor positive 1 | 18
Apraxias 1 | 27
Ascites 1 | 22
Biliary cirrhosis 1 | 45
Brain hemorrhage 1 | 14
C-reactive protein increased 1 | 15
Calcinosis 1 | 70
Cerebral Hemorrhage 1 | 42
Cerebral Ischemia 1 | 37
Colitis, Ulcerative 1 | 59
Depressed mood 1 | 17
Dyspnea on exertion 1 | 24
ESR raised 1 | 20
Elevated C-reactive protein level 1 | 15
Elevated IgE 1 | 10
Embolism and Thrombosis 1 | 6
Familial thrombocytosis 1 | 3
Florid red complexion (finding) 1 | 3
Gastrointestinal Hemorrhage 1 | 52
Growth Disorders 1 | 35
Growth Hormone-Secreting Pituitary Adenoma 1 | 6
Heart Valve Diseases 1 | 25
Heart valve disease 1 | 39
Hematocrit increased 1 | 5
Hemoglobin increased 1 | 6
Hypertension, Portal 1 | 22
Hypopituitarism 1 | 40
Immunologic Deficiency Syndromes 1 | 113
Increased megakaryocyte count 1 | 6
Increased red blood cell mass 1 | 4
Insulin Resistance 1 | 72
Iridocyclitis 1 | 19
Isolated growth hormone deficiency 1 | 30
Isolated somatotropin deficiency 1 | 30
Job's syndrome 1 | 3
Joint swelling 1 | 26
Juvenile rheumatoid arthritis 1 | 111
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Liver Cirrhosis, Biliary 1 | 33
Liver Neoplasms, Experimental 1 | 59
Lymphoma, Primary Cutaneous Anaplastic Large Cell 1 | 2
Lymphomatoid Papulosis 1 | 2
MYELODYSPLASTIC SYNDROME 1 | 53
Malocclusion 1 | 57
Mammary Neoplasms, Experimental 1 | 154
Mastitis 1 | 48
Muscular atrophy 1 | 71
Myeloproliferative Disorders 1 | 7
Narcolepsy 1 | 72
Non-alcoholic Fatty Liver Disease 1 | 42
Paranoia 1 | 20
Pauciarticular juvenile rheumatoid arthritis 1 | 9
Peripheral thrombosis 1 | 3
Polyarthritis 1 | 11
Portal hypertension 1 | 20
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1 | 25
Primary Myelofibrosis 1 | 5
Primary polycythemia 1 | 8
Recurrent fungal infections 1 | 13
Recurrent viral infections 1 | 15
THROMBOCYTHEMIA 3 1 | 3
Thromboembolism 1 | 15
Type 1 diabetes mellitus 1 | 109
Tyrosine Kinase 2 Deficiency 1 | 1
Weight Gain 1 | 100

Tissue

Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Respiratory system 5 | 16,393
Cardiovascular System 4 | 15,192
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Kinase 3 | 634
Non-IDG 2 | 12,091

GO Function

growth hormone receptor bindin... 5 | 5
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Non-receptor tyrosine-protein kinase TYK2 TYK2 Tclin Kinase -2.47105 252.9 547
Somatotropin GH1 Tbio Non-IDG -3.03406 1736.7 722
Suppressor of cytokine signaling 2 SOCS2 Tbio Non-IDG -2.90841 804.7 196
Tyrosine-protein kinase JAK1 JAK1 Tclin Kinase -2.80024 518.7 425
Tyrosine-protein kinase JAK2 JAK2 Tclin Kinase -3.54037 3339.7 801