Development Level

Tbio 17 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal kidney morphology 1 | 65
abnormal spleen morphology 1 | 55
decreased body weight 1 | 161
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74

Disease

Carcinoma 18 | 11,493
ovarian cancer 13 | 8,520
invasive ductal carcinoma 11 | 2,951
lung carcinoma 11 | 2,843
interstitial cystitis 10 | 2,312
lung adenocarcinoma 10 | 2,716
non-small cell lung cancer 10 | 2,890
psoriasis 10 | 6,694
ductal carcinoma in situ 9 | 1,745
glioblastoma 9 | 5,792
lung cancer 9 | 4,740
pancreatic cancer 9 | 2,398
breast carcinoma 8 | 1,638
cystic fibrosis 8 | 1,696
ependymoma 8 | 4,679
Breast cancer 7 | 3,578
Cancer 7 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
medulloblastoma, large-cell 7 | 6,241
Astrocytoma, Pilocytic 6 | 3,081
Duchenne muscular dystrophy 6 | 601
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
cutaneous lupus erythematosus 6 | 1,057
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
malignant mesothelioma 6 | 3,232
osteosarcoma 6 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
adrenocortical carcinoma 5 | 1,428
colon cancer 5 | 1,478
group 3 medulloblastoma 5 | 4,104
pituitary cancer 5 | 1,972
ulcerative colitis 5 | 1,819
Atopic dermatitis 4 | 952
Kidney cancer 4 | 2,613
Pick disease 4 | 1,894
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
gastric carcinoma 4 | 807
limb girdle muscular dystrophy 2A 4 | 213
primary pancreatic ductal adenocarcinoma 4 | 1,109
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 658
Atherosclerosis 3 | 291
Down syndrome 3 | 499
Epilepsy 3 | 792
Hypotrophic malar bone 3 | 129
Malar flattening 3 | 129
Myopia 3 | 176
Osteoarthritis 3 | 184
Seizures 3 | 596
acute quadriplegic myopathy 3 | 1,158
fibroadenoma 3 | 559
juvenile dermatomyositis 3 | 1,187
mucosa-associated lymphoid tissue lymphoma 3 | 484
oligodendroglioma 3 | 2,850
pterygium 3 | 76
sonic hedgehog group medulloblastoma 3 | 467
tuberculosis 3 | 2,010
ANEURYSM, INTRACRANIAL BERRY, 1 (disorder) 2 | 3
Becker muscular dystrophy 2 | 191
Brachydactyly 2 | 156
COPD 2 | 118
Ehlers-Danlos syndrome 2 | 43
Endometriosis 2 | 540
Eye Abnormalities 2 | 35
Flexion contracture of proximal interphalangeal joint 2 | 75
Gaucher disease type 1 2 | 180
Glaucoma 2 | 239
Hernia, Inguinal 2 | 89
Hydronephrosis 2 | 89
Hypertension 2 | 396
Hypoplastic mandible condyle 2 | 275
Hypotrophic midface 2 | 105
Intermittent migraine headaches 2 | 68
Liver Cirrhosis, Experimental 2 | 769
Mandibular hypoplasia 2 | 275
Melanoma 2 | 711
Midface retrusion 2 | 105
Migraine Disorders 2 | 76
Retrognathia 2 | 54
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Small midface 2 | 105
Type 2 diabetes mellitus 2 | 272
Vascular disease 2 | 319
X-linked cerebral adrenoleukodystrophy 2 | 116
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
chronic lymphosyte leukemia 2 | 204
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
facioscapulohumeral dystrophy 2 | 288
inflammatory breast cancer 2 | 286
posterior fossa group B ependymoma 2 | 416
primary Sjogren syndrome 2 | 735
urothelial carcinoma 2 | 318

Tissue

Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Male tissues 20 | 17,142
Nervous System 20 | 16,725
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678
Blood and immune system 19 | 16,909
Digestive Tract 19 | 17,369
Respiratory system 19 | 16,393
Cardiovascular System 18 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 3 | 4,145
Kinase 1 | 634

GO Function

glycosaminoglycan binding 20 | 20
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Epiphycan EPYC Tbio Non-IDG -1.62043 40.7 82
Versican core protein VCAN Tbio Non-IDG -2.88501 795.4 190
Latent-transforming growth factor beta-binding protein 4 LTBP4 Tbio Non-IDG -1.55113 39.1 57
Exostosin-like 2 EXTL2 Tbio Enzyme -1.08858 13.8 124
Pikachurin EGFLAM Tbio Non-IDG -2.31248 207.9 70
Testican-2 SPOCK2 Tbio Non-IDG -0.87419 6.75 57
Protein NDNF NDNF Tbio Non-IDG -2.41790 249.2 74
Hyaluronan-binding protein 2 HABP2 Tbio Enzyme -2.52006 357.1 177
Transforming growth factor beta receptor type 3 TGFBR3 Tbio Non-IDG -1.92250 80.6 270