Development Level

Tbio 14 | 11,445
Tchem 5 | 1,598
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal testis morphology 1 | 43
absent optic nerve 1 | 2
decreased circulating insulin ... 1 | 76
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
hydrometra 1 | 53
increased erythrocyte cell num... 1 | 39
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
prenatal lethality prior to he... 1 | 87
small testis 1 | 58

Disease

ovarian cancer 11 | 8,520
Cancer 8 | 2,499
osteosarcoma 8 | 7,950
psoriasis 8 | 6,694
Carcinoma 7 | 11,493
Schizophrenia 7 | 1,160
glioblastoma 7 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung cancer 7 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
tuberculosis 6 | 2,010
Lung Neoplasms 5 | 232
Multiple myeloma 5 | 1,332
Prostatic Neoplasms 5 | 495
diabetes mellitus 5 | 1,728
interstitial cystitis 5 | 2,312
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
Breast Neoplasms 4 | 445
Keshan disease 4 | 17
Mammary Neoplasms 4 | 425
Myocardial Ischemia 4 | 169
adrenocortical carcinoma 4 | 1,428
atypical teratoid / rhabdoid tumor 4 | 5,112
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary pancreatic ductal adenocarcinoma 4 | 1,109
Asthma 3 | 385
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Bladder Neoplasm 3 | 112
Breast cancer 3 | 3,578
Chemical and Drug Induced Liver Injury 3 | 195
Hypertension 3 | 396
Neurodegenerative Diseases 3 | 38
Neurodegenerative Disorders 3 | 79
Non-alcoholic Fatty Liver Disease 3 | 42
Urinary Bladder Neoplasms 3 | 114
acute quadriplegic myopathy 3 | 1,158
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
invasive ductal carcinoma 3 | 2,951
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Acute kidney injury 2 | 70
Amphetamine-Related Disorders 2 | 74
Autistic Disorder 2 | 364
Bipolar Disorder 2 | 666
Carcinoma, Hepatocellular 2 | 228
Carcinoma, Non-Small-Cell Lung 2 | 107
Carcinoma, Renal Cell 2 | 124
Cognitive delay 2 | 608
Contact Dermatitis 2 | 81
Depressive disorder 2 | 409
Dermatitis, Contact 2 | 71
Down syndrome 2 | 499
Drug allergy 2 | 36
Endometriosis 2 | 540
Epilepsy 2 | 792
Fatty Liver 2 | 70
Global developmental delay 2 | 608
Heart failure 2 | 162
Hypertensive disease 2 | 292
Liver Cirrhosis, Experimental 2 | 769
Liver carcinoma 2 | 240
Liver neoplasms 2 | 130
Male infertility 2 | 206
Mental Depression 2 | 333
Mental and motor retardation 2 | 608
Muscle hypotonia 2 | 571
Neoplasms 2 | 63
Obesity 2 | 678
Osteoarthritis 2 | 184
Parkinson Disease 2 | 64
Psychotic Disorders 2 | 151
Renal Cell Carcinoma 2 | 214
Rheumatoid arthritis 2 | 1,191
Vascular disease 2 | 319
Xeroderma pigmentosum group D 2 | 33
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
adult high grade glioma 2 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
group 3 medulloblastoma 2 | 4,104
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung carcinoma 2 | 317
primary Sjogren syndrome 2 | 735

Tissue

Male tissues 19 | 17,142
Endocrine System 18 | 18,159
Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678
Cardiovascular System 15 | 15,192

Target Family

Enzyme 18 | 4,145
Ion Channel 1 | 344
Non-IDG 1 | 12,091

GO Function

glutathione peroxidase activit... 20 | 20
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Maleylacetoacetate isomerase GSTZ1 Tbio Enzyme -1.99892 99.5 150
Phospholipid hydroperoxide glutathione peroxidase, mitochondrial GPX4 Tbio Enzyme -2.88891 707.6 227
Microsomal glutathione S-transferase 1 MGST1 Tbio Enzyme -2.30082 197.5 146
Leukotriene C4 synthase LTC4S Tchem Enzyme -1.98032 93.9 89
Glutathione peroxidase 2 GPX2 Tbio Enzyme -2.29928 197.6 144
Peroxiredoxin-6 PRDX6 Tbio Non-IDG -2.63290 435.3 425
Epididymal secretory glutathione peroxidase GPX5 Tbio Enzyme -1.87343 72.2 59
Chloride intracellular channel protein 2 CLIC2 Tbio Ion Channel -1.51704 30.1 115
Glutathione peroxidase 6 GPX6 Tdark Enzyme -1.61002 37.5 32
Glutathione peroxidase 3 GPX3 Tbio Enzyme -2.68271 472.3 196