Development Level

Tbio 7 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

increased mean corpuscular hem... 2 | 96
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal lung morphology 1 | 26
abnormal spleen morphology 1 | 55
anophthalmia 1 | 33
decreased fasted circulating g... 1 | 65
edema 1 | 59
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased fasted circulating g... 1 | 76
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
small kidney 1 | 16

Disease

ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
Carcinoma 6 | 11,493
Cancer 5 | 2,499
Chemical and Drug Induced Liver Injury 5 | 195
Neurodegenerative Diseases 4 | 38
Neurodegenerative Disorders 4 | 79
Schizophrenia 4 | 1,160
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
Breast cancer 3 | 3,578
Prostatic Neoplasms 3 | 495
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
osteosarcoma 3 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
tuberculosis 3 | 2,010
Acute kidney injury 2 | 70
Amphetamine-Related Disorders 2 | 74
Asthma 2 | 385
Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Bladder Neoplasm 2 | 112
Carcinoma, Hepatocellular 2 | 228
Carcinoma, Non-Small-Cell Lung 2 | 107
Carcinoma, Renal Cell 2 | 124
Chloracne 2 | 32
Chromosome Aberrations 2 | 16
Chronic obstructive pulmonary disease 2 | 184
Colorectal Neoplasms 2 | 243
Contact Dermatitis 2 | 81
Dermatitis, Contact 2 | 71
Drug Hypersensitivity 2 | 34
Drug allergy 2 | 36
Dull intelligence 2 | 645
Epilepsy 2 | 792
Hypertension 2 | 396
Intellectual disability 2 | 1,016
Kidney Diseases 2 | 114
Liver carcinoma 2 | 240
Low intelligence 2 | 645
Lung Neoplasms 2 | 232
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Metabolic acidosis 2 | 90
Myocardial Ischemia 2 | 169
Neutrophil count decreased 2 | 47
Non-alcoholic Fatty Liver Disease 2 | 42
Parkinson Disease 2 | 64
Poor school performance 2 | 645
Renal Cell Carcinoma 2 | 214
Retinitis Pigmentosa 2 | 226
Seizures 2 | 596
Urinary Bladder Neoplasms 2 | 114
Xeroderma pigmentosum group D 2 | 33
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
non-small cell lung carcinoma 2 | 317
pituitary cancer 2 | 1,972
sarcoidosis 2 | 370
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Anemia, Megaloblastic 1 | 16
Animal Mammary Neoplasms 1 | 136
Anorexia 1 | 43
Breast Neoplasms 1 | 445
Bruxism 1 | 18
Carcinoma, Squamous Cell 1 | 110
Cocaine Dependence 1 | 51
Confusion 1 | 21
Decreased platelet count 1 | 111
Essential tremor 1 | 28
Extrapyramidal Disorders 1 | 29
Extrapyramidal sign 1 | 29
Fatigue 1 | 182
Glioma 1 | 74
Kidney Calculi 1 | 7
Kidney damage 1 | 25
Lethargy 1 | 77
Liver Neoplasms, Experimental 1 | 59
Liver disease 1 | 237
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Mouth Diseases 1 | 12
Nonorganic psychosis 1 | 84
Pallor 1 | 40
Peripheral Neuropathy 1 | 134
Precancerous Conditions 1 | 80
Sarcoma 1 | 62
Skin Diseases 1 | 71
Squamous cell carcinoma 1 | 129
Thyroid Neoplasm 1 | 37
Thyroid Neoplasms 1 | 34
fascioscapulohumeral muscular dystrophy 1 | 100

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Enzyme 9 | 4,145
Non-IDG 2 | 12,091

GO Function

glutathione binding 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methylmalonic aciduria and homocystinuria type C protein MMACHC Tbio Non-IDG -1.83573 76.5 233
Glutathione synthetase GSS Tbio Enzyme -2.78139 592.8 229
Microsomal glutathione S-transferase 1 MGST1 Tbio Enzyme -2.30082 197.5 146
Prostaglandin E synthase PTGES Tchem Enzyme -3.05403 1164.2 151
Glutathione S-transferase Mu 1 GSTM1 Tbio Enzyme -3.27893 1991.1 469
Glutathione S-transferase Mu 4 GSTM4 Tbio Enzyme -1.21233 13.7 95
LanC-like protein 1 LANCL1 Tbio Non-IDG -1.08292 11.5 73
Glutathione S-transferase Mu 2 GSTM2 Tchem Enzyme -2.23927 166.1 164
Glutathione S-transferase P GSTP1 Tchem Enzyme -3.20051 1734.8 519
Prostaglandin E synthase 2 PTGES2 Tchem Enzyme -1.65834 34.9 176