Development Level

Tchem 8 | 1,598
Tclin 2 | 613
Tbio 1 | 11,445

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

increased circulating triglyce... 2 | 42
abnormal eye morphology 1 | 68
cataract 1 | 92
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
increased circulating choleste... 1 | 66
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased mean platelet volume 1 | 45
limb grasping 1 | 41
microphthalmia 1 | 26
mydriasis 1 | 6

Disease

Carcinoma 11 | 11,493
Kidney cancer 9 | 2,613
Schizophrenia 9 | 1,160
medulloblastoma, large-cell 8 | 6,241
Alcoholic Intoxication, Chronic 7 | 289
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
Bipolar Disorder 6 | 666
Epilepsy 6 | 792
Melanoma 6 | 711
adult high grade glioma 6 | 3,801
glioblastoma 6 | 5,792
psoriasis 6 | 6,694
Epilepsy, Temporal Lobe 5 | 23
Liver cancer 5 | 604
Mental Depression 5 | 333
Skin cancer 5 | 469
Toxic encephalopathy 5 | 141
astrocytic glioma 5 | 2,597
group 3 medulloblastoma 5 | 4,104
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
Alcohol dependence 4 | 107
Astrocytoma, Pilocytic 4 | 3,081
Attention Deficit Disorder with Hyperactivity 4 | 21
Attention deficit hyperactivity disorder 4 | 278
Autistic Disorder 4 | 364
Depressive disorder 4 | 409
Major Depressive Disorder 4 | 301
Parkinson's disease 4 | 392
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
Autosomal recessive predisposition 3 | 1,442
Fragile X syndrome 3 | 34
Intellectual disability 3 | 1,016
Unipolar Depression 3 | 250
Acquired immunodeficiency syndrome 2 | 197
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Atrophy of cerebellum 2 | 103
Breast cancer 2 | 3,578
Cerebellar Ataxia 2 | 304
Cerebellar Dysmetria 2 | 56
Cerebellar degeneration 2 | 103
Cocaine-Related Disorders 2 | 92
Cognitive delay 2 | 608
Dysarthria 2 | 192
Dysdiadochokinesis 2 | 25
Endometrial cancer 2 | 311
Epilepsy characterized by intractable complex partial seizures 2 | 28
Esotropia 2 | 31
Global developmental delay 2 | 608
Infantile onset 2 | 238
Infratentorial atrophy 2 | 103
Lennox-Gastaut syndrome 2 | 34
Mental and motor retardation 2 | 608
Migraine Prevention 2 | 23
Mood Disorders 2 | 184
Muscle hypotonia 2 | 571
Neurodegenerative disease 2 | 414
Pick disease 2 | 1,894
Simple partial seizure 2 | 26
Small Cell Lung Carcinoma 2 | 41
Small cell carcinoma of lung 2 | 45
Spinocerebellar Ataxias 2 | 34
Status Epilepticus 2 | 98
Substance-Related Disorders 2 | 115
Tonic-clonic epilepsy 2 | 47
addicted to cocaine 2 | 4
osteosarcoma 2 | 7,950
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
Abnormal coordination 1 | 15
Acquired metabolic disease 1 | 336
Blepharoptosis 1 | 231
Congenital stationary night blindness 1 | 29
DOID:2627 1 | 94
Difficulties with night vision 1 | 87
Dilated ventricles (finding) 1 | 121
Gait Ataxia 1 | 51
Gastroesophageal reflux disease 1 | 110
Gliosis 1 | 56
Hemeralopia 1 | 4
Hyperactive behavior 1 | 91
Hyperreflexia 1 | 209
Hypotrichosis 1 1 | 15
Impaired cognition 1 | 96
Local anesthesia 1 | 40
Mental impairment 1 | 95
Myopia 1 | 176
Narcolepsy 1 | 72
Nerve Degeneration 1 | 121
Neuralgia 1 | 20
Night Blindness 1 | 101
Night blindness, congenital stationary 1 | 16
Pain agnosia 1 | 104
Partial seizure 1 | 15
Retinal Degeneration 1 | 106
Slow progression 1 | 89
Tremor 1 | 113

Tissue

Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Nervous System 11 | 16,725
Digestive Tract 9 | 17,369
Male tissues 9 | 17,142
Skin and soft tissues 9 | 17,230
Respiratory system 8 | 16,393
Urinary Tract 8 | 16,678
Blood and immune system 7 | 16,909
Liver and Pancreas 7 | 16,750
Cardiovascular System 4 | 15,192

Target Family

GPCR 8 | 408
Ion Channel 3 | 344

GO Function

glutamate receptor activity 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Metabotropic glutamate receptor 3 GRM3 Tchem GPCR -2.30964 186.9 274
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
Metabotropic glutamate receptor 4 GRM4 Tchem GPCR -2.34335 217.2 150
Glutamate receptor ionotropic, delta-2 GRID2 Tbio Ion Channel -2.05105 116.1 74
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396
Metabotropic glutamate receptor 8 GRM8 Tchem GPCR -1.95032 89.4 286
Metabotropic glutamate receptor 6 GRM6 Tchem GPCR -1.98705 92.3 263
Metabotropic glutamate receptor 1 GRM1 Tchem GPCR -3.05662 1115.6 490
Metabotropic glutamate receptor 2 GRM2 Tchem GPCR -2.77035 612.3 315
Glutamate receptor 1 GRIA1 Tclin Ion Channel -3.17077 1441.5 761