Development Level

Tbio 8 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

abnormal retina morphology 1 | 71
cardiovascular system phenotyp... 1 | 36
decreased basophil cell number 1 | 16
decreased eosinophil cell numb... 1 | 24
decreased heart rate variabili... 1 | 13
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased or absent threshold ... 1 | 101
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 5 | 11,493
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
Cataract 4 | 297
Erythrokeratodermia variabilis 4 | 10
pancreatic cancer 4 | 2,398
Alopecia 3 | 115
Autosomal recessive predisposition 3 | 1,442
Cancer 3 | 2,499
Clouston syndrome 3 | 9
Deafness, autosomal recessive 1A 3 | 4
Epilepsy 3 | 792
Erythema 3 | 58
Flushing 3 | 60
Hyperkeratosis, generalized 3 | 14
Infantile onset 3 | 238
Lens Opacities 3 | 231
Myopia 3 | 176
Palmoplantar keratosis 3 | 74
Small head 3 | 374
adult high grade glioma 3 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
medulloblastoma, large-cell 3 | 6,241
psoriasis 3 | 6,694
ulcerative colitis 3 | 1,819
Abnormal blistering of the skin 2 | 54
Adenoma 2 | 167
Autistic Disorder 2 | 364
Blister of skin 2 | 54
Breast cancer 2 | 3,578
Cataract, Pulverulent 2 | 11
Charcot-Marie-Tooth disease 2 | 62
Conductive hearing loss 2 | 123
Congenital pes cavus 2 | 88
Corneal diameter decreased 2 | 47
Cortical white matter abnormalities seen on MRI 2 | 18
DEAFNESS, AUTOSOMAL RECESSIVE 1A (disorder) 2 | 3
Deafness 2 | 198
Dry skin 2 | 75
Dull intelligence 2 | 645
Dysarthria 2 | 192
Dystrophic fingernails 2 | 18
Enlarged vestibular aqueduct 2 | 10
Exanthema 2 | 43
Fine hair 2 | 42
Frontal bossing 2 | 157
Glaucoma 2 | 239
Hearing Loss, Sensorineural 2 | 11
Hyperpigmented macules 2 | 42
Intellectual disability 2 | 1,016
Leukoaraiosis 2 | 18
Low Vision 2 | 174
Low intelligence 2 | 645
Lung Neoplasms 2 | 232
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Microcornea 2 | 47
Microphthalmia 2 | 76
Nail dysplasia 2 | 52
Neuropathy 2 | 261
Nonsyndromic deafness 2 | 142
Nuclear cataract 2 | 19
Nuclear non-senile cataract 2 | 18
Oculodentodigital dysplasia 2 | 14
Paraparesis 2 | 6
Patchy palmoplantar keratoderma 2 | 3
Photosensitivity of skin 2 | 51
Poor school performance 2 | 645
Schizophrenia 2 | 1,160
Sensorineural Hearing Loss (disorder) 2 | 284
Sensorineural hearing loss 2 | 106
Short stature 2 | 531
Skin Neoplasms 2 | 69
Skin bulla 2 | 54
Sparse eyelashes 2 | 31
Sparse hair 2 | 59
Thin, sparse hair 2 | 59
Visual Impairment 2 | 174
Weight decreased 2 | 103
X- linked recessive 2 | 110
Xerosis 2 | 75
breast carcinoma 2 | 1,638
cataract 2 multiple types 2 | 9
diabetes mellitus 2 | 1,728
facioscapulohumeral dystrophy 2 | 288
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
Craniofacial hyperostosis 1 | 11
Enlargement of craniofacial bones 1 | 11
Hypertrophy of craniofacial bones 1 | 11
Thick craniofacial bones 1 | 11

Tissue

Endocrine System 10 | 18,159
Urinary Tract 9 | 16,678
Female tissues 8 | 17,400
Digestive Tract 7 | 17,369
Liver and Pancreas 7 | 16,750
Nervous System 7 | 16,725
Skin and soft tissues 7 | 17,230
Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Male tissues 6 | 17,142
Respiratory system 6 | 16,393

Target Family

Non-IDG 10 | 12,091

GO Function

gap junction channel activity 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gap junction alpha-1 protein GJA1 Tbio Non-IDG -3.59195 4122.5 889
Gap junction beta-2 protein GJB2 Tbio Non-IDG -3.17642 1514.7 242
Gap junction beta-1 protein GJB1 Tbio Non-IDG -2.93115 861.6 295
Gap junction alpha-8 protein GJA8 Tbio Non-IDG -2.81282 660.2 196
Gap junction delta-2 protein GJD2 Tbio Non-IDG -2.48933 326.9 192
Gap junction alpha-3 protein GJA3 Tbio Non-IDG -2.14059 135.1 171
Gap junction beta-3 protein GJB3 Tbio Non-IDG -2.13572 133.9 212
Gap junction delta-3 protein GJD3 Tbio Non-IDG -0.48785 4.49 23
Gap junction beta-7 protein GJB7 Tdark Non-IDG -0.50515 3.41 50
Gap junction alpha-10 protein GJA10 Tdark Non-IDG 0.15 0.90 51