Development Level

Tbio 18 | 11,445
Tdark 4 | 6,588
Tchem 2 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal gait 2 | 69
decreased grip strength 2 | 116
abnormal craniofacial morpholo... 1 | 33
abnormal limb bud morphology 1 | 17
abnormal maxilla morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
decreased bone mineral density 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
edema 1 | 59
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating serum al... 1 | 22
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
pale liver 1 | 6
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 19 | 11,493
ovarian cancer 14 | 8,520
medulloblastoma, large-cell 13 | 6,241
osteosarcoma 11 | 7,950
Breast cancer 9 | 3,578
group 3 medulloblastoma 9 | 4,104
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
malignant mesothelioma 8 | 3,232
subependymal giant cell astrocytoma 8 | 2,287
colon cancer 7 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung cancer 7 | 4,740
psoriasis 7 | 6,694
adult high grade glioma 6 | 3,801
Short stature 5 | 531
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
primitive neuroectodermal tumor 5 | 3,035
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Bipolar Disorder 4 | 666
Cancer 4 | 2,499
Cognitive delay 4 | 608
Dull intelligence 4 | 645
Global developmental delay 4 | 608
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Poor school performance 4 | 645
Schizophrenia 4 | 1,160
Small head 4 | 374
ependymoma 4 | 4,679
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
pediatric high grade glioma 4 | 1,064
tuberculosis and treatment for 6 months 4 | 409
Acquired scoliosis 3 | 281
Anemia 3 | 365
Atopic dermatitis 3 | 952
Autistic Disorder 3 | 364
Congenital clinodactyly 3 | 57
Curvature of digit 3 | 57
Curvature of spine 3 | 282
Pick disease 3 | 1,894
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
interstitial cystitis 3 | 2,312
non primary Sjogren syndrome sicca 3 | 891
pancreatic cancer 3 | 2,398
primary Sjogren syndrome 3 | 735
progressive supranuclear palsy 3 | 676
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Abnormality of retinal pigmentation 2 | 111
Abnormally small eyeball 2 | 97
Anteverted nostril 2 | 191
Broad flat nasal bridge 2 | 236
Congenital Epicanthus 2 | 177
Deafness 2 | 198
Decreased size of eyeball 2 | 97
Depressive disorder 2 | 409
Epilepsy 2 | 792
Glaucoma 2 | 239
Hearing Loss, Partial 2 | 185
Isolated cases 2 | 72
Liver Cirrhosis, Experimental 2 | 769
Long narrow head 2 | 75
Narrow cranium shape 2 | 75
Narrow head shape 2 | 75
Narrow skull shape 2 | 75
Nasal bridge wide 2 | 236
Prenatal onset 2 | 139
Prostatic Neoplasms 2 | 495
Retinal pigment epithelial abnormality 2 | 111
Seizures 2 | 596
Turridolichocephaly 2 | 75
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
atypical teratoid/rhabdoid tumor 2 | 357
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 416
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Blood and immune system 26 | 16,909
Cardiovascular System 26 | 15,192
Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678

Target Family

Non-IDG 20 | 12,091
Kinase 4 | 634
Enzyme 2 | 4,145

GO Function

gamma-tubulin binding 26 | 26
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Centrosomal protein of 57 kDa CEP57 Tbio Non-IDG -0.98216 11.8 177
Biogenesis of lysosome-related organelles complex 1 subunit 2 BLOC1S2 Tbio Non-IDG -2.89123 759.6 79
Rab11 family-interacting protein 5 RAB11FIP5 Tbio Non-IDG -1.52843 34.5 62
Gamma-tubulin complex component 6 TUBGCP6 Tbio Non-IDG -0.76777 4.81 83
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945
Breast cancer type 2 susceptibility protein BRCA2 Tbio Non-IDG -3.46139 2647.6 209
cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B Tclin Enzyme -2.13222 124.3 341
Serine/threonine-protein kinase BRSK1 BRSK1 Tchem Kinase -1.44039 28.9 301
Centrosomal protein CEP57L1 CEP57L1 Tdark Non-IDG -0.32451 2.10 64
Oral-facial-digital syndrome 1 protein OFD1 Tbio Non-IDG -1.91225 84.6 54