Development Level

Tbio 10 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal heart morphology 1 | 162
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63

Disease

Carcinoma 11 | 11,493
ovarian cancer 10 | 8,520
atypical teratoid / rhabdoid tumor 8 | 5,112
medulloblastoma, large-cell 8 | 6,241
Cancer 7 | 2,499
Kidney cancer 7 | 2,613
psoriasis 7 | 6,694
ependymoma 6 | 4,679
interstitial cystitis 6 | 2,312
malignant mesothelioma 6 | 3,232
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
glioblastoma 5 | 5,792
group 4 medulloblastoma 5 | 1,855
osteosarcoma 5 | 7,950
primitive neuroectodermal tumor 5 | 3,035
Breast Neoplasms 4 | 445
Colorectal Neoplasms 4 | 243
Melanoma 4 | 711
Pick disease 4 | 1,894
Skin cancer 4 | 469
breast carcinoma 4 | 1,638
esophageal adenocarcinoma 4 | 737
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
pancreatic cancer 4 | 2,398
pediatric high grade glioma 4 | 1,064
Colonic Neoplasms 3 | 142
Neoplasm Invasiveness 3 | 161
Neoplasm Metastasis 3 | 168
Prostatic Neoplasms 3 | 495
Stomach Neoplasms 3 | 300
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
dermatomyositis 3 | 966
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
pituitary cancer 3 | 1,972
Acquired metabolic disease 2 | 336
Adenocarcinoma 2 | 122
Adenoma 2 | 167
Animal Mammary Neoplasms 2 | 136
Bipolar Disorder 2 | 666
Carcinoma of colon 2 | 32
Cardiovascular system disease 2 | 246
Cell Transformation, Neoplastic 2 | 97
Chronic Lymphocytic Leukemia 2 | 262
Dermatitis 2 | 157
Disease Models, Animal 2 | 155
Disease Progression 2 | 136
Endometrial cancer 2 | 311
Hereditary Diffuse Gastric Cancer 2 | 3
Hypotrichosis 2 | 47
Lymphoid leukemia 2 | 160
Mammary Neoplasms 2 | 425
Mammary Neoplasms, Animal 2 | 136
Mesothelioma 2 | 38
Multiple Sclerosis 2 | 540
Neoplasm of stomach 2 | 11
Neoplastic Cell Transformation 2 | 89
Nerve Degeneration 2 | 121
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Stomach Carcinoma 2 | 11
Stomach cancer 2 | 30
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
medulloblastoma 2 | 720
pancreatic carcinoma 2 | 562
primary pancreatic ductal adenocarcinoma 2 | 1,109
ulcerative colitis 2 | 1,819
Adenomatous Polyposis Coli 1 | 16
Carcinoma, Lobular 1 | 6
Eosinophilic esophagitis 1 | 16
Esophagitis 1 | 35
Familial cancer of breast 1 | 12
Hyperglycemia 1 | 137
Keloid 1 | 37
Leiomyosarcoma of uterus 1 | 13
Liver Neoplasms, Experimental 1 | 59
Lobular neoplasia 1 | 15
Malignant tumor of colon 1 | 19
Micronodular cirrhosis 1 | 12
Pilomatrixoma 1 | 12
Prostatic Intraepithelial Neoplasia 1 | 11
Prostatic Intraepithelial Neoplasias 1 | 11
Sebaceous Gland Neoplasms 1 | 1
Transitional cell carcinoma of bladder 1 | 17

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Liver and Pancreas 10 | 16,750
Respiratory system 10 | 16,393

Target Family

Non-IDG 6 | 12,091
Enzyme 3 | 4,145
Transcription Factor 2 | 1,400

GO Function

gamma-catenin binding 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Receptor-type tyrosine-protein phosphatase eta PTPRJ Tbio Enzyme -1.98955 114.2 298
Receptor-type tyrosine-protein phosphatase T PTPRT Tbio Enzyme -1.35450 23.1 83
Cadherin-2 CDH2 Tbio Non-IDG -3.19431 1382.9 993
Cadherin-1 CDH1 Tbio Non-IDG -3.85201 6324.3 1880
Desmocollin-3 DSC3 Tbio Non-IDG -2.47398 295.5 177
Desmoglein-1 DSG1 Tbio Non-IDG -2.72159 516.2 406
Adenomatous polyposis coli protein APC Tbio Non-IDG -1.90646 66.5 508
Lymphoid enhancer-binding factor 1 LEF1 Tchem Transcription Factor -2.60971 375.2 591
Catenin alpha-1 CTNNA1 Tbio Non-IDG -1.94479 78.1 488
Receptor-type tyrosine-protein phosphatase kappa PTPRK Tbio Enzyme -1.45578 31.0 34