Development Level

Tbio 6 | 11,445
Tchem 3 | 1,598

Disease

lung cancer 7 | 4,740
medulloblastoma, large-cell 6 | 6,241
psoriasis 6 | 6,694
Breast cancer 5 | 3,578
Cancer 5 | 2,499
ovarian cancer 5 | 8,520
Carcinoma 4 | 11,493
Short stature 4 | 531
adult high grade glioma 4 | 3,801
glioblastoma 4 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
osteosarcoma 4 | 7,950
Bloom syndrome 3 | 29
Fanconi anemia 3 | 56
Intellectual disability 3 | 1,016
Small head 3 | 374
Werner syndrome 3 | 29
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
atypical teratoid / rhabdoid tumor 3 | 5,112
diabetes mellitus 3 | 1,728
group 3 medulloblastoma 3 | 4,104
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
Alzheimer's disease 2 | 658
Autosomal recessive predisposition 2 | 1,442
Azoospermia 2 | 110
Birthmark 2 | 35
Cafe-au-Lait Spots 2 | 37
Calcium pyrophosphate deposition disease 2 | 13
Chromosome Breakage 2 | 36
Cockayne syndrome 2 | 60
Cognitive delay 2 | 608
Decreased fertility in females 2 | 20
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diarrhea 2 | 253
Dull intelligence 2 | 645
Global developmental delay 2 | 608
Increased chromosomal breakage 2 | 27
Kidney cancer 2 | 2,613
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Myocardial Infarction 2 | 151
Narrow face 2 | 54
Nijmegen breakage syndrome 2 | 24
Osteoporosis 2 | 363
Poor school performance 2 | 645
Rothmund-Thomson syndrome 2 | 19
Thin face 2 | 54
Waldenstrons macroglobulinemia 2 | 765
Xeroderma pigmentosum 2 | 43
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
juvenile dermatomyositis 2 | 1,187
pancreatic cancer 2 | 2,398
Absent upper lateral incisors 1 | 3
Agenesis of maxillary lateral incisor 1 | 3
Almond-shaped eyes 1 | 23
Angiofibroma 1 | 7
Carney complex 1 | 25
Convex nasal ridge 1 | 37
Decreased circulating ACTH level 1 | 12
Decreased male fertility 1 | 7
Galactorrhea 1 | 5
Growth hormone excess 1 | 14
Hematologic Neoplasms 1 | 22
High pitched voice 1 | 23
Hyperinsulinaemic hypoglycaemia 1 | 16
Hyperinsulinemic hypoglycemia 1 | 17
Hyperphagia 1 | 23
Hyperphosphaturia 1 | 21
Increased appetite (finding) 1 | 23
Increased serum parathyroid hormone 1 | 14
Lack of skin elasticity 1 | 10
Micronuclei, Chromosome-Defective 1 | 25
Multiple Endocrine Neoplasia Type 1 1 | 29
Multiple endocrine neoplasia type 2B 1 | 17
Osteosclerosis 1 | 31
Paranasal Sinus Diseases 1 | 34
Parathyroid Adenoma 1 | 19
Parathyroid carcinoma 1 | 7
Peptic Ulcer 1 | 27
Pyridoxine-responsive sideroblastic anemia 1 | 17
Secondary hypothyroidism 1 | 15
Slender build 1 | 14
Stretched skin 1 | 10
Thyroid Gland Follicular Adenoma 1 | 9
Tuberous sclerosis 1 | 19
Urine phosphorous concentration above normal 1 | 21
Zollinger-Ellison syndrome 1 | 18
menstrual periods stopped for over 6 months 1 | 13

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 4 | 12,091
Transcription Factor 4 | 1,400
Enzyme 1 | 4,145

GO Function

four-way junction DNA binding 9 | 9
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA repair protein RAD51 homolog 1 RAD51 Tchem Non-IDG -3.82649 6590.0 594
High mobility group protein B1 HMGB1 Tbio Transcription Factor -3.05199 2190.4 1145
Menin MEN1 Tchem Non-IDG -3.23460 1803.0 382
Transcriptional repressor protein YY1 YY1 Tbio Transcription Factor -2.80737 619.7 475
Werner syndrome ATP-dependent helicase WRN Tbio Enzyme -2.73759 569.7 210
Bloom syndrome protein BLM Tchem Non-IDG -2.03028 104.1 314
High mobility group protein B2 HMGB2 Tbio Transcription Factor -1.52510 34.5 267
High mobility group protein B3 HMGB3 Tbio Transcription Factor -1.48799 33.1 199
Meiotic recombination protein DMC1/LIM15 homolog DMC1 Tbio Non-IDG -1.16534 16.4 260