Development Level

Tchem 4 | 1,598
Tbio 2 | 11,445

IMPC Phenotype

abnormal allantois morphology 1 | 8
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal left-right axis patte... 1 | 2
abnormal limb bud morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal somite shape 1 | 5
abnormal tail bud morphology 1 | 8
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased leukocyte cell numbe... 1 | 73
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, complete... 1 | 979
small testis 1 | 58

Disease

biotin-responsive basal ganglia disease 5 | 8
non-small cell lung cancer 5 | 2,890
Malignant mesothelioma of pleura 4 | 7
psoriasis 4 | 6,694
Acute lymphoid leukemia 3 | 25
Breast cancer 3 | 3,578
Burkitt's lymphoma 3 | 15
Carcinoma 3 | 11,493
Carcinoma of female breast 3 | 20
Gestational trophoblastic neoplasia 3 | 14
Juvenile rheumatoid arthritis 3 | 111
Liver Cirrhosis, Experimental 3 | 769
Malignant tumor of head and/or neck 3 | 15
Malignant tumor of lung 3 | 5
Meningeal Leukemia 3 | 7
Mycosis fungoides 3 | 29
Non-Hodgkin's lymphoma 3 | 22
Osteosarcoma of bone 3 | 6
Rheumatoid arthritis 3 | 1,191
adrenocortical carcinoma 3 | 1,428
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
spina bifida 3 | 1,074
Alcoholic Intoxication, Chronic 2 | 289
Anemia 2 | 365
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Colonic Neoplasms 2 | 142
Myelomeningocele 2 | 16
Neural Tube Defects 2 | 31
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010
Abnormal vision 1 | 52
Adenocarcinoma of lung 1 | 142
Adverse reaction to drug 1 | 61
Alcohol dependence 1 | 107
Anorexia 1 | 43
Atrial Septal Defects 1 | 85
Autistic Disorder 1 | 364
Bladder Neoplasm 1 | 112
Cardiac Arrhythmia 1 | 103
Cardiac conduction abnormalities 1 | 78
Colorectal Neoplasms 1 | 243
Conduction disorder of the heart 1 | 79
Cone dystrophy 1 | 71
Congenital Heart Defects 1 | 58
Craniofacial Abnormalities 1 | 151
Decreased platelet count 1 | 111
Dermatologic disorders 1 | 93
Developmental regression 1 | 95
Diarrhea 1 | 253
Disease Models, Animal 1 | 155
Drug-Related Side Effects and Adverse Reactions 1 | 62
EKG abnormalities 1 | 78
Electrocardiogram abnormal 1 | 81
Electrocardiogram change 1 | 78
Headache 1 | 37
Heart Defects, Congenital 1 | 37
Hoarseness 1 | 31
Hyperhomocysteinemia 1 | 37
Lethargy 1 | 77
Loss of developmental milestones 1 | 95
Mental deterioration in childhood 1 | 95
Nerve Degeneration 1 | 121
Nervous System Diseases 1 | 53
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Neurodegenerative disease 1 | 414
Neurodevelopmental regression 1 | 95
Osteoarthritis 1 | 184
Ovarian Neoplasms 1 | 102
Pallor 1 | 40
Pancytopenia 1 | 45
Paresthesia 1 | 32
Psychomotor regression 1 | 95
Psychomotor regression beginning in infancy 1 | 95
Psychomotor regression in infants 1 | 95
Psychomotor regression, progressive 1 | 95
Retinal Degeneration 1 | 106
Sensorineural Hearing Loss (disorder) 1 | 284
Sensorineural hearing loss 1 | 106
Sideroblastic anemia 1 | 20
Thrombocytopenia 1 | 197
Urinary Bladder Neoplasms 1 | 114
Wernicke encephalopathy 1 | 12
cystic fibrosis and chronic rhinosinusitis 1 | 214
interstitial lung disease 1 | 298
nervous system disorder 1 | 53
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Transporter 4 | 473
Non-IDG 2 | 12,091

GO Function

folic acid transporter activit... 6 | 6
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Proton-coupled folate transporter SLC46A1 Tchem Transporter -2.23182 177.1 76
Folate transporter 1 SLC19A1 Tchem Transporter -2.00363 97.7 67
Folate receptor beta FOLR2 Tchem Non-IDG -1.91119 88.6 222
Mitochondrial folate transporter/carrier SLC25A32 Tbio Transporter -1.31880 19.7 48
Thiamine transporter 1 SLC19A2 Tbio Transporter -2.02810 109.1 49