Development Level

Tbio 15 | 11,445
Tchem 7 | 1,598
Tclin 4 | 613
Tdark 1 | 6,588

IMPC Phenotype

enlarged heart 3 | 210
abnormal heart morphology 2 | 162
abnormal liver morphology 2 | 17
abnormal lung morphology 2 | 26
increased bone mineral content 2 | 108
short tibia 2 | 97
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal seminal vesicle morph... 1 | 114
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
enlarged testis 1 | 6
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased bone mineral density 1 | 72
increased heart weight 1 | 62
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
kinked tail 1 | 2
mammalian phenotype 1 | 17
mydriasis 1 | 6
small superior vagus ganglion 1 | 74

Disease

Carcinoma 20 | 11,493
ovarian cancer 18 | 8,520
Cancer 16 | 2,499
glioblastoma 16 | 5,792
pancreatic cancer 15 | 2,398
Breast cancer 13 | 3,578
diabetes mellitus 13 | 1,728
osteosarcoma 13 | 7,950
Astrocytoma, Pilocytic 12 | 3,081
cystic fibrosis 12 | 1,696
primary pancreatic ductal adenocarcinoma 12 | 1,109
psoriasis 12 | 6,694
tuberculosis 11 | 2,010
interstitial cystitis 10 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
invasive ductal carcinoma 10 | 2,951
medulloblastoma, large-cell 10 | 6,241
ependymoma 9 | 4,679
lung adenocarcinoma 9 | 2,716
lung carcinoma 9 | 2,843
non-small cell lung cancer 9 | 2,890
atypical teratoid / rhabdoid tumor 8 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
pituitary cancer 8 | 1,972
Kidney cancer 7 | 2,613
Liver Cirrhosis, Experimental 7 | 769
adrenocortical carcinoma 7 | 1,428
adult high grade glioma 7 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
group 3 medulloblastoma 7 | 4,104
malignant mesothelioma 7 | 3,232
Arthritis 6 | 290
Atopic dermatitis 6 | 952
Duchenne muscular dystrophy 6 | 601
Kidney disease 6 | 430
Obesity 6 | 678
Schizophrenia 6 | 1,160
gastric carcinoma 6 | 807
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
juvenile dermatomyositis 6 | 1,187
lung cancer 6 | 4,740
pediatric high grade glioma 6 | 1,064
primary Sjogren syndrome 6 | 735
ulcerative colitis 6 | 1,819
Rheumatoid arthritis 5 | 1,191
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
cutaneous lupus erythematosus 5 | 1,057
dermatomyositis 5 | 966
limb girdle muscular dystrophy 2A 5 | 213
primitive neuroectodermal tumor 5 | 3,035
Atherosclerosis 4 | 291
Heart disease 4 | 306
Osteoporosis 4 | 363
Prostatic Neoplasms 4 | 495
active Crohn's disease 4 | 922
acute quadriplegic myopathy 4 | 1,158
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
mucosa-associated lymphoid tissue lymphoma 4 | 484
nasopharyngeal carcinoma 4 | 1,058
subependymal giant cell astrocytoma 4 | 2,287
Arthritis, Rheumatoid 3 | 174
Autistic Disorder 3 | 364
Autosomal recessive predisposition 3 | 1,442
Becker muscular dystrophy 3 | 191
Breast Neoplasms 3 | 445
Carcinoma, Non-Small-Cell Lung 3 | 107
Cerebral Hemorrhage 3 | 42
Cerebrovascular accident 3 | 63
Cerebrovascular disease 3 | 238
Chronic hepatitis C 3 | 12
Contact Dermatitis 3 | 81
Coronary artery disease 3 | 268
Dermatitis, Contact 3 | 71
Diabetic retinopathy 3 | 56
Endometriosis 3 | 540
Glaucoma 3 | 239
Gliosis 3 | 56
Heart failure 3 | 162
Hypertension 3 | 396
Liver Cirrhosis 3 | 181
Mammary Neoplasms 3 | 425
Multiple Sclerosis 3 | 540
Polycystic ovary syndrome 3 | 360
Proteinuria 3 | 144
Stroke 3 | 33
Vascular disease 3 | 319
interstitial lung disease 3 | 298
medulloblastoma 3 | 720
non-small cell lung carcinoma 3 | 317
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Bipolar Disorder 2 | 666
Mental Depression 2 | 333
Myocardial Ischemia 2 | 169
Proliferative vitreoretinopathy 2 | 17
astrocytoma 2 | 1,146
nephrosclerosis 2 | 333
spina bifida 2 | 1,074

Tissue

Female tissues 27 | 17,400
Digestive Tract 26 | 17,369
Skin and soft tissues 26 | 17,230
Blood and immune system 25 | 16,909
Endocrine System 25 | 18,159
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Urinary Tract 25 | 16,678
Cardiovascular System 24 | 15,192

Target Family

Non-IDG 21 | 12,091
Enzyme 6 | 4,145

GO Function

fibronectin binding 27 | 27
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
Very-long-chain 3-oxoacyl-CoA reductase HSD17B12 Tbio Enzyme -1.58879 36.7 136
Insulin-like growth factor-binding protein 5 IGFBP5 Tchem Non-IDG -2.52721 351.8 278
Fibulin-1 FBLN1 Tbio Non-IDG -1.97380 101.1 218
Integrin alpha-4 ITGA4 Tclin Non-IDG -2.53262 310.4 1312
Coiled-coil domain-containing protein 80 CCDC80 Tbio Non-IDG -1.83025 70.8 65
Cathepsin S CTSS Tchem Enzyme -3.31099 1955.9 291
Apolipoprotein(a) LPA Tbio Enzyme -3.51111 3598.6 227
Follistatin-related protein 3 FSTL3 Tbio Non-IDG -1.80964 76.6 138
Uncharacterized protein C6orf15 C6orf15 Tdark Non-IDG -2.78801 624.4 14