Development Level

Tbio 19 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 3 | 278
abnormal embryo size 2 | 220
abnormal retinal vasculature m... 2 | 27
cataract 2 | 92
impaired pupillary reflex 2 | 26
increased circulating choleste... 2 | 66
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal tail morphology 1 | 25
absent startle reflex 1 | 24
cleft palate 1 | 8
corneal opacity 1 | 32
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased spleen weight 1 | 10
decreased threshold for audito... 1 | 26
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
fused cornea and lens 1 | 5
hemorrhage 1 | 23
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
limb grasping 1 | 41
narrow eye opening 1 | 12
no spontaneous movement 1 | 1
persistence of hyaloid vascula... 1 | 33

Disease

Cancer 11 | 2,499
Carcinoma 10 | 11,493
lung cancer 9 | 4,740
invasive ductal carcinoma 8 | 2,951
malignant mesothelioma 8 | 3,232
osteosarcoma 7 | 7,950
psoriasis 7 | 6,694
Breast cancer 6 | 3,578
Cleft Lip 6 | 141
Cleft Palate 6 | 271
diabetes mellitus 6 | 1,728
ovarian cancer 6 | 8,520
cystic fibrosis 5 | 1,696
glioblastoma 5 | 5,792
medulloblastoma, large-cell 5 | 6,241
non-small cell lung cancer 5 | 2,890
Autosomal recessive predisposition 4 | 1,442
LADD syndrome 4 | 9
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
pituitary cancer 4 | 1,972
ulcerative colitis 4 | 1,819
Breast Neoplasms 3 | 445
Carcinoma, Hepatocellular 3 | 228
Depressive disorder 3 | 409
Down syndrome 3 | 499
Liver carcinoma 3 | 240
Lung disease 3 | 142
Mammary Neoplasms 3 | 425
Obesity 3 | 678
Parkinson's disease 3 | 392
Pulmonary Fibrosis 3 | 106
Synostosis 3 | 15
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
oligodendroglioma 3 | 2,850
Abnormality of the voice 2 | 46
Abortion, Spontaneous 2 | 109
Achondroplasia 2 | 21
Acrocephalosyndactylia 2 | 17
Alzheimer's disease 2 | 658
Anosmia 2 | 22
Anterior hypopituitarism 2 | 18
Congenital absence of kidney 2 | 31
Congenital hypoplasia of breast 2 | 25
Congenital hypoplasia of penis 2 | 176
Craniofacial Abnormalities 2 | 151
Craniosynostosis 2 | 74
Cryptorchidism 2 | 296
Decreased bone mineral density Z score 2 | 31
Decreased fertility 2 | 33
Delayed Puberty 2 | 97
Diabetes Mellitus, Type 2 2 | 142
Downward slant of palpebral fissure 2 | 158
Erectile abnormalities 2 | 16
Fatty liver disease 2 | 103
Gynecomastia 2 | 64
Heart disease 2 | 306
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Hypospadias 2 | 53
Hypothalamic gonadotropin-releasing hormone deficiency 2 | 14
Irritable bowel syndrome 2 | 60
Kallmann syndrome 2 | 33
Kidney Diseases 2 | 114
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Klinefelter's syndrome 2 | 56
Liver Cirrhosis 2 | 181
Mesothelioma 2 | 38
Mucositis 2 | 29
Myocardial Ischemia 2 | 169
Orbital separation excessive 2 | 244
Osteoporosis 2 | 363
Polydactyly 2 | 107
Primary physiologic amenorrhea 2 | 55
Prostatic Neoplasms 2 | 495
Renal agenesis 2 | 29
Reperfusion Injury 2 | 86
Sense of smell impaired 2 | 21
Small testicle 2 | 75
Spontaneous abortion 2 | 113
Vascular disease 2 | 319
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
fibroadenoma 2 | 559
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
pancreatic cancer 2 | 2,398
tuberculosis 2 | 2,010
Hernia, Diaphragmatic 1 | 40
Xerostomia 1 | 42

Tissue

Endocrine System 21 | 18,159
Digestive Tract 19 | 17,369
Nervous System 19 | 16,725
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678
Blood and immune system 17 | 16,909
Cardiovascular System 15 | 15,192
Respiratory system 15 | 16,393

Target Family

Non-IDG 20 | 12,091
Enzyme 2 | 4,145

GO Function

fibroblast growth factor recep... 22 | 22
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibroblast growth factor 2 FGF2 Tchem Non-IDG -4.00542 10573.5 798
Fibroblast growth factor 1 FGF1 Tchem Non-IDG -3.21050 1645.9 514
Fibroblast growth factor receptor substrate 2 FRS2 Tbio Non-IDG -2.37203 224.0 344
Fibroblast growth factor 9 FGF9 Tbio Non-IDG -2.30869 217.7 272
Klotho KL Tbio Enzyme -2.86543 790.6 276
Fibroblast growth factor 5 FGF5 Tbio Non-IDG -2.07061 109.8 192
Leucine-rich repeat transmembrane protein FLRT3 FLRT3 Tbio Non-IDG -1.29335 20.6 58
Fibroblast growth factor 7 FGF7 Tbio Non-IDG -3.16409 1534.1 267
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.55166 363.0 320
Fibroblast growth factor 8 FGF8 Tbio Non-IDG -2.73368 532.0 299