Development Level

Tbio 7 | 11,445
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

embryonic lethality prior to o... 2 | 239
preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278

Disease

Autosomal recessive predisposition 5 | 1,442
Carcinoma 4 | 11,493
lung cancer 4 | 4,740
Cancer 3 | 2,499
Depressive disorder 3 | 409
Neoplasm Invasiveness 3 | 161
Obesity 3 | 678
atypical teratoid / rhabdoid tumor 3 | 5,112
medulloblastoma, large-cell 3 | 6,241
psoriasis 3 | 6,694
Aceruloplasminemia 2 | 16
Alcoholic Intoxication, Chronic 2 | 289
Arthritis 2 | 290
Babinski Reflex 2 | 100
Brain disease 2 | 96
Cerebellar Ataxia 2 | 304
Congestive heart failure 2 | 113
Dysarthria 2 | 192
Dystonia 2 | 164
Friedreich ataxia 2 | 24
Gait Ataxia 2 | 51
Heart failure 2 | 162
Hemochromatosis 2 | 54
Hyperferritinaemia 2 | 14
Hypertension 2 | 396
Increased ferritin 2 | 14
Iron Overload 2 | 5
Keloid 2 | 37
Kidney disease 2 | 430
Mesothelioma, Malignant 2 | 105
Muscle Rigidity 2 | 49
Nerve Degeneration 2 | 121
Neurodegeneration with brain iron accumulation 3 2 | 8
Neurodegenerative Disorders 2 | 79
Neurodegenerative disease 2 | 414
Optic Atrophy 2 | 242
Parkinsonian Disorders 2 | 56
Restless legs syndrome 2 | 27
Schizophrenia 2 | 1,160
Serum ferritin increased 2 | 14
Tremor 2 | 113
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Action Tremor 1 | 22
Adenocarcinoma of lung (disorder) 1 | 60
Alcoholism 1 | 45
Areflexia of lower limbs 1 | 9
Arthropathy 1 | 43
Ataxia, Appendicular 1 | 25
Atransferrinemia 1 | 8
Cherubism 1 | 13
Choreoathetoid movements 1 | 32
Choreoathetosis 1 | 32
Combined immunodeficiency 1 | 5
Decreased CSF homovanillic acid 1 | 3
Decreased amplitude of sensory action potentials 1 | 2
Degenerative disc disease 1 | 35
Delirium 1 | 10
Dysphonia 1 | 7
Dystonia, Limb 1 | 9
Favorable response to levodopa 1 | 6
Heart Diseases 1 | 43
Hepatitis 1 | 67
Heredodegenerative Disorders, Nervous System 1 | 3
Hyperostosis 1 | 18
Hyperprolactinemia 1 | 27
Hypochromic anemia 1 | 9
Iron Metabolism Disorders 1 | 5
Iron deficiency anemia 1 | 12
Irregular vertebral endplates 1 | 16
Laryngeal dystonia 1 | 5
Learning Disorders 1 | 29
Little's Disease 1 | 14
Metaphyseal irregularity 1 | 23
Microcytic hypochromic anemia (disorder) 1 | 10
Mutism 1 | 17
Narrow nose 1 | 20
Neurodegeneration with brain iron accumulation 1 | 20
Neurodegenerative Diseases 1 | 38
Ollier disease 1 | 18
Peripheral sensory axonal neuropathy 1 | 7
Pheochromocytoma 1 | 24
Platyspondyly 1 | 56
Sensory axonal neuropathy 1 | 7
Spastic Ataxia 1 | 18
Spondylolisthesis 1 | 22
Substance abuse 1 | 59
Synovitis 1 | 78
T-Lymphocytopenia 1 | 9
Terminal tremor 1 | 20
Type 1 diabetes mellitus 1 | 109

Tissue

Endocrine System 9 | 18,159
Skin and soft tissues 8 | 17,230
Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Urinary Tract 7 | 16,678
Respiratory system 6 | 16,393
Cardiovascular System 5 | 15,192

Target Family

Non-IDG 7 | 12,091
Enzyme 3 | 4,145

GO Function

ferric iron binding 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Ferritin light chain FTL Tbio Non-IDG -2.36162 227.3 549
Ferritin heavy polypeptide-like 17 FTHL17 Tdark Non-IDG -0.94371 8.18 33
Putative ferritin heavy polypeptide-like 19 FTH1P19 Tdark Non-IDG 0.00000 0
Ferritin, mitochondrial FTMT Tbio Non-IDG -1.11598 13.8 34
Frataxin, mitochondrial FXN Tbio Non-IDG -3.02739 1114.8 403
Inositol oxygenase MIOX Tbio Enzyme -1.73181 60.0 146
Ferritin heavy chain FTH1 Tbio Non-IDG -3.00480 982.1 562
Tartrate-resistant acid phosphatase type 5 ACP5 Tbio Enzyme -3.35274 1913.6 333
Tyrosine 3-monooxygenase TH Tclin Enzyme -3.49790 2144.6 1203