Development Level

Tclin 16 | 613
Tbio 2 | 11,445

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
decreased body weight 1 | 161
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 18 | 11,493
Schizophrenia 17 | 1,160
Bipolar Disorder 14 | 666
Kidney cancer 14 | 2,613
atypical teratoid / rhabdoid tumor 13 | 5,112
medulloblastoma, large-cell 13 | 6,241
Epilepsy 11 | 792
General anesthesia 11 | 53
Lennox-Gastaut syndrome 11 | 34
Local anesthesia 11 | 40
Simple partial seizure 11 | 26
ependymoma 11 | 4,679
glioblastoma 11 | 5,792
Epilepsy characterized by intractable complex partial seizures 9 | 28
Migraine Prevention 9 | 23
Tonic-clonic epilepsy 9 | 47
adult high grade glioma 9 | 3,801
astrocytic glioma 9 | 2,597
group 3 medulloblastoma 9 | 4,104
oligodendroglioma 9 | 2,850
primitive neuroectodermal tumor 9 | 3,035
psoriasis 9 | 6,694
Parkinson's disease 8 | 392
lung carcinoma 8 | 2,843
Alcoholism 7 | 45
Arteriosclerotic Parkinsonism 7 | 8
Astrocytoma, Pilocytic 7 | 3,081
Extrapyramidal disease 7 | 8
Influenza A Prevention 7 | 7
Influenza due to Influenza A virus 7 | 7
Melanoma 7 | 711
Parkinsonism 7 | 18
Postencephalitic parkinsonism 7 | 12
Toxic encephalopathy 7 | 141
Depressive disorder 6 | 409
Intellectual disability 6 | 1,016
Major Depressive Disorder 6 | 301
Mental Depression 6 | 333
Skin cancer 6 | 469
osteosarcoma 6 | 7,950
subependymal giant cell astrocytoma 6 | 2,287
Alcoholic Intoxication, Chronic 5 | 289
Autistic Disorder 5 | 364
Liver cancer 5 | 604
Pick disease 5 | 1,894
Alzheimer's disease 4 | 658
Dull intelligence 4 | 645
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Moderate to Severe Alzheimer's Type Dementia 4 | 5
Partial seizure 4 | 15
Poor school performance 4 | 645
lung cancer 4 | 4,740
ovarian cancer 4 | 8,520
Alcohol dependence 3 | 107
Attention deficit hyperactivity disorder 3 | 278
Cocaine-Related Disorders 3 | 92
Cognitive delay 3 | 608
Global developmental delay 3 | 608
Huntington's disease 3 | 76
Mental and motor retardation 3 | 608
Psychosexual Disorders 3 | 6
Psychotic Disorders 3 | 151
Seizures 3 | 596
Sexual Dysfunctions, Psychological 3 | 6
Substance Withdrawal Syndrome 3 | 55
Unipolar Depression 3 | 250
group 4 medulloblastoma 3 | 1,855
non primary Sjogren syndrome sicca 3 | 891
pituitary cancer 3 | 1,972
Amyotrophic lateral sclerosis 2 | 451
Autosomal recessive predisposition 2 | 1,442
Brain Ischemia 2 | 110
Breast cancer 2 | 3,578
Cardiovascular system disease 2 | 246
Cerebrovascular disease 2 | 238
Colorectal Neoplasms 2 | 243
Encephalitis 2 | 64
Endometrial cancer 2 | 311
High pressure neurological syndrome 2 | 9
Highly variable severity 2 | 157
Hyperactive behavior 2 | 91
Hyperalgesia 2 | 83
Hyperkinesis 2 | 32
Hypotension 2 | 82
Infantile onset 2 | 238
Large intestine cancer 2 | 126
Mood Disorders 2 | 184
Morphine dependence 2 | 16
Muscle hypotonia 2 | 571
Neurodegenerative disease 2 | 414
Opiate dependence 2 | 29
Substance-Related Disorders 2 | 115
Variable expressivity 2 | 157
Vascular disease 2 | 319
gastric carcinoma 2 | 807
lingual-facial-buccal dyskinesia 2 | 13
lung adenocarcinoma 2 | 2,716
pediatric high grade glioma 2 | 1,064

Tissue

Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Nervous System 18 | 16,725
Female tissues 17 | 17,400
Male tissues 17 | 17,142
Skin and soft tissues 17 | 17,230
Blood and immune system 16 | 16,909
Respiratory system 16 | 16,393
Urinary Tract 16 | 16,678
Liver and Pancreas 15 | 16,750
Cardiovascular System 11 | 15,192

Target Family

Ion Channel 18 | 344

GO Function

extracellular-glutamate-gated ... 18 | 18
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutamate receptor ionotropic, delta-2 GRID2 Tbio Ion Channel -2.05105 116.1 74
Glutamate receptor ionotropic, kainate 4 GRIK4 Tclin Ion Channel -2.19499 147.3 105
Glutamate receptor ionotropic, kainate 5 GRIK5 Tclin Ion Channel -2.11616 127.3 179
Glutamate receptor ionotropic, NMDA 3A GRIN3A Tclin Ion Channel -1.89138 80.5 24
Glutamate receptor ionotropic, NMDA 3B GRIN3B Tclin Ion Channel -1.43696 28.3 121
Glutamate receptor ionotropic, NMDA 2A GRIN2A Tclin Ion Channel -3.09828 1158.1 555
Glutamate receptor ionotropic, kainate 1 GRIK1 Tclin Ion Channel -2.44487 279.7 219
Glutamate receptor ionotropic, NMDA 2C GRIN2C Tclin Ion Channel -2.21470 153.6 208
Glutamate receptor ionotropic, delta-1 GRID1 Tbio Ion Channel -1.07838 10.7 166
Glutamate receptor 4 GRIA4 Tclin Ion Channel -2.43418 256.1 326