Development Level

Tbio 58 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal kidney morphology 2 | 65
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
impaired glucose tolerance 2 | 75
increased heart weight 2 | 62
persistence of hyaloid vascula... 2 | 33
abnormal coat-hair pigmentatio... 1 | 64
abnormal femur morphology 1 | 14
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal tail morphology 1 | 25
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
dilated heart left ventricle 1 | 11
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased large unstained cell... 1 | 5
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
polycystic kidney 1 | 15

Disease

Carcinoma 56 | 11,493
ovarian cancer 41 | 8,520
Breast cancer 34 | 3,578
glioblastoma 34 | 5,792
lung cancer 32 | 4,740
psoriasis 32 | 6,694
Kidney cancer 31 | 2,613
medulloblastoma, large-cell 31 | 6,241
pancreatic cancer 31 | 2,398
Astrocytoma, Pilocytic 30 | 3,081
atypical teratoid / rhabdoid tumor 28 | 5,112
ependymoma 28 | 4,679
adult high grade glioma 27 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
invasive ductal carcinoma 24 | 2,951
osteosarcoma 24 | 7,950
interstitial cystitis 23 | 2,312
group 3 medulloblastoma 22 | 4,104
lung adenocarcinoma 22 | 2,716
malignant mesothelioma 22 | 3,232
pituitary cancer 22 | 1,972
ulcerative colitis 22 | 1,819
Duchenne muscular dystrophy 21 | 601
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
breast carcinoma 20 | 1,638
cystic fibrosis 20 | 1,696
gastric carcinoma 20 | 807
primitive neuroectodermal tumor 20 | 3,035
nasopharyngeal carcinoma 19 | 1,058
non-small cell lung cancer 19 | 2,890
ductal carcinoma in situ 18 | 1,745
primary pancreatic ductal adenocarcinoma 17 | 1,109
colon cancer 16 | 1,478
lung carcinoma 16 | 2,843
Melanoma 15 | 711
Skin cancer 15 | 469
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 510
subependymal giant cell astrocytoma 15 | 2,287
juvenile dermatomyositis 14 | 1,187
oligodendroglioma 14 | 2,850
pterygium 14 | 76
Autosomal recessive predisposition 13 | 1,442
Liver Cirrhosis, Experimental 13 | 769
adrenocortical carcinoma 13 | 1,428
limb girdle muscular dystrophy 2A 13 | 213
Becker muscular dystrophy 12 | 191
Myopia 12 | 176
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
urothelial carcinoma 12 | 318
Degenerative polyarthritis 11 | 115
Liver cancer 11 | 604
Osteoarthritis 11 | 184
diabetes mellitus 11 | 1,728
esophageal adenocarcinoma 11 | 737
interstitial lung disease 10 | 298
non primary Sjogren syndrome sicca 10 | 891
Atopic dermatitis 9 | 952
Joint hyperflexibility 9 | 78
Short stature 9 | 531
acute quadriplegic myopathy 9 | 1,158
dermatomyositis 9 | 966
Cancer 8 | 2,499
Hypertensive disease 8 | 292
Mitral Valve Prolapse Syndrome 8 | 39
Pectus excavatum 8 | 100
cutaneous lupus erythematosus 8 | 1,057
head and neck cancer and chronic obstructive pulmonary disease 8 | 239
Abortion, Spontaneous 7 | 109
Acquired scoliosis 7 | 281
Cataract 7 | 297
Congenital pectus carinatum 7 | 52
Curvature of spine 7 | 282
Ehlers-Danlos syndrome 7 | 43
Glaucoma 7 | 239
Hernia, Inguinal 7 | 89
Hypoplastic mandible condyle 7 | 275
Mandibular hypoplasia 7 | 275
Micrognathism 7 | 275
Pick disease 7 | 1,894
Platyspondyly 7 | 56
Rheumatoid arthritis 7 | 1,191
Soft skin 7 | 17
Spontaneous abortion 7 | 113
Velvety skin 7 | 17
X-linked cerebral adrenoleukodystrophy 7 | 116
active Crohn's disease 7 | 922
fibroadenoma 7 | 559
group 4 medulloblastoma 7 | 1,855
medulloblastoma 7 | 720
pediatric high grade glioma 7 | 1,064
posterior fossa group A ependymoma 7 | 468
Atherosclerosis 6 | 291
Congenital Epicanthus 6 | 177
Kidney disease 6 | 430
Liver Cirrhosis 6 | 181
Range of joint movement increased 6 | 32
Respiratory Insufficiency 6 | 132
astrocytic glioma 6 | 2,597
astrocytoma 6 | 1,146

Tissue

Endocrine System 58 | 18,159
Digestive Tract 57 | 17,369
Female tissues 57 | 17,400
Male tissues 57 | 17,142
Nervous System 57 | 16,725
Skin and soft tissues 57 | 17,230
Liver and Pancreas 55 | 16,750
Urinary Tract 53 | 16,678
Blood and immune system 52 | 16,909
Respiratory system 52 | 16,393
Cardiovascular System 47 | 15,192

Target Family

Non-IDG 61 | 12,091
Enzyme 1 | 4,145

GO Function

extracellular matrix structura... 62 | 62
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
EGF-containing fibulin-like extracellular matrix protein 2 EFEMP2 Tbio Non-IDG -1.67314 52.3 243
Beta-tectorin TECTB Tbio Non-IDG -1.23705 16.8 72
Hyaluronan and proteoglycan link protein 4 HAPLN4 Tbio Non-IDG -0.76903 6.57 156
Collagen alpha-1(XV) chain COL15A1 Tbio Non-IDG -1.18716 15.5 74
Collagen alpha-1(XI) chain COL11A1 Tbio Non-IDG -2.15516 138.4 96
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
Elastin ELN Tbio Non-IDG -3.36288 2144.5 299
Dentin sialophosphoprotein DSPP Tbio Non-IDG -2.88022 744.2 49
Collagen alpha-1(XIX) chain COL19A1 Tbio Non-IDG -0.75672 6.18 137
Collagen alpha-2(V) chain COL5A2 Tbio Non-IDG -1.69982 44.6 96