Development Level

Tbio 17 | 11,445
Tclin 3 | 613
Tchem 2 | 1,598
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
enlarged kidney 1 | 14
increased heart weight 1 | 62
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
prolonged ST segment 1 | 36

Disease

Carcinoma 20 | 11,493
ovarian cancer 16 | 8,520
glioblastoma 15 | 5,792
Breast cancer 13 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
pancreatic cancer 13 | 2,398
invasive ductal carcinoma 12 | 2,951
psoriasis 12 | 6,694
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Astrocytoma, Pilocytic 10 | 3,081
Cancer 10 | 2,499
breast carcinoma 10 | 1,638
lung cancer 10 | 4,740
osteosarcoma 10 | 7,950
atypical teratoid / rhabdoid tumor 9 | 5,112
ependymoma 9 | 4,679
lung adenocarcinoma 9 | 2,716
primary pancreatic ductal adenocarcinoma 9 | 1,109
ulcerative colitis 9 | 1,819
adult high grade glioma 8 | 3,801
colon cancer 8 | 1,478
cystic fibrosis 8 | 1,696
ductal carcinoma in situ 8 | 1,745
malignant mesothelioma 8 | 3,232
non-small cell lung cancer 8 | 2,890
adrenocortical carcinoma 7 | 1,428
diabetes mellitus 7 | 1,728
interstitial cystitis 7 | 2,312
medulloblastoma, large-cell 7 | 6,241
tuberculosis 7 | 2,010
Atherosclerosis 6 | 291
Autosomal recessive predisposition 6 | 1,442
Kidney cancer 6 | 2,613
group 3 medulloblastoma 6 | 4,104
group 4 medulloblastoma 6 | 1,855
limb girdle muscular dystrophy 2A 6 | 213
oligodendroglioma 6 | 2,850
Cerebral Hemorrhage 5 | 42
Duchenne muscular dystrophy 5 | 601
Liver Cirrhosis, Experimental 5 | 769
gastric carcinoma 5 | 807
lung carcinoma 5 | 2,843
Atopic dermatitis 4 | 952
Cerebrovascular disease 4 | 238
Coronary artery disease 4 | 268
Degenerative disc disease 4 | 35
Endometriosis 4 | 540
Glanzmann's thrombasthenia 4 | 23
Heart disease 4 | 306
Liver Cirrhosis 4 | 181
Osteoarthritis 4 | 184
Rheumatoid arthritis 4 | 1,191
acute quadriplegic myopathy 4 | 1,158
cutaneous lupus erythematosus 4 | 1,057
esophageal adenocarcinoma 4 | 737
pancreatic carcinoma 4 | 562
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
Anemia 3 | 365
Arthritis 3 | 290
Arthritis, Rheumatoid 3 | 174
Becker muscular dystrophy 3 | 191
Cataract 3 | 297
Cerebrovascular accident 3 | 63
Down syndrome 3 | 499
Kidney disease 3 | 430
Multiple Sclerosis 3 | 540
Myocardial Ischemia 3 | 169
Myopia 3 | 176
Neoplasms, Experimental 3 | 40
Osteochondrodysplasias 3 | 72
Osteoporosis 3 | 363
Pick disease 3 | 1,894
Short stature 3 | 531
Stroke 3 | 33
Thrombocytopenia 3 | 197
astrocytic glioma 3 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
gastric cancer 3 | 459
interstitial lung disease 3 | 298
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
non primary Sjogren syndrome sicca 3 | 891
posterior fossa group A ependymoma 3 | 468
primitive neuroectodermal tumor 3 | 3,035
spina bifida 3 | 1,074
urothelial carcinoma 3 | 318
Colonic Neoplasms 2 | 142
Epilepsy 2 | 792
Hemoglobin low 2 | 124
Hypertension 2 | 396
Lung Neoplasms 2 | 232
Lung disease 2 | 142
Polycystic ovary syndrome 2 | 360
Proteinuria 2 | 144
Retinal Detachment 2 | 51
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764

Tissue

Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 18 | 12,091
Enzyme 2 | 4,145
GPCR 2 | 408
Transcription Factor 1 | 1,400

GO Function

extracellular matrix binding 23 | 23
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
Endosialin CD248 Tbio Non-IDG -3.07620 1180.8 253
Collagen alpha-1(XI) chain COL11A1 Tbio Non-IDG -2.15516 138.4 96
A disintegrin and metalloproteinase with thrombospondin motifs 5 ADAMTS5 Tchem Enzyme -2.26251 168.4 371
Transforming growth factor-beta-induced protein ig-h3 TGFBI Tbio Non-IDG -2.63615 441.5 287
A disintegrin and metalloproteinase with thrombospondin motifs 15 ADAMTS15 Tbio Enzyme -0.68544 5.17 77
Testican-2 SPOCK2 Tbio Non-IDG -0.87419 6.75 57
Integrin alpha-IIb ITGA2B Tclin Non-IDG -3.52120 3309.8 1170
Olfactomedin-like protein 2A OLFML2A Tdark Non-IDG -0.09691 1.53 112
SPARC-like protein 1 SPARCL1 Tbio Non-IDG -1.58295 41.0 195