Development Level

Tbio 3 | 11,445
Tchem 1 | 1,598

Disease

Glycoproteinosis 4 | 12
Carcinoma 2 | 11,493
Gangliosidosis 2 | 20
psoriasis 2 | 6,694
Abnormal skeletal development 1 | 60
Abnormal urinary amino-acid findings 1 | 38
Abnormally-shaped vertebrae 1 | 31
Acquired scoliosis 1 | 281
Aminoaciduria 1 | 38
Ascites 1 | 22
Astrocytoma, Pilocytic 1 | 3,081
Autosomal recessive predisposition 1 | 1,442
Broad flat nasal bridge 1 | 236
Cardiomegaly 1 | 116
Cardiomyopathies 1 | 110
Cataract 1 | 297
Cerebellar Ataxia 1 | 304
Cerebellar Dysmetria 1 | 56
Cherry red spot of the macula 1 | 7
Cholera 1 | 34
Clouding of corneal stroma 1 | 50
Coarse facial features 1 | 108
Congenital pectus carinatum 1 | 52
Corneal Opacity 1 | 53
Curvature of spine 1 | 282
Decreased nerve conduction velocity 1 | 35
Decreased visual acuity, progressive 1 | 36
Delayed bone age 1 | 136
Discrete subaortic stenosis 1 | 2
Dull intelligence 1 | 645
Electroencephalogram abnormal 1 | 101
Epilepsy 1 | 792
Facial edema 1 | 1
Frontal bossing 1 | 157
Full lower lip 1 | 64
Gait abnormality 1 | 135
Gas gangrene 1 | 17
Hepatomegaly 1 | 285
Hernia 1 | 9
Hernia, Inguinal 1 | 89
Hydrops Fetalis 1 | 21
Hyperkeratosis 1 | 50
Hyperreflexia 1 | 209
Increased urinary O-linked sialopeptides 1 | 2
Increased urinary sialyloligosaccharides 1 | 1
Intellectual disability 1 | 1,016
Large vacuolated foam cells ('NP cells') on bone marrow biopsy 1 | 5
Lens Opacities 1 | 231
Lipomucopolysaccharidosis 1 | 1
Low Vision 1 | 174
Low intelligence 1 | 645
Mastitis 1 | 48
Mental Retardation 1 | 645
Mental deficiency 1 | 645
Multiple myeloma 1 | 1,332
Muscle Weakness 1 | 170
Muscle hypotonia 1 | 571
Myoclonic Epilepsies, Progressive 1 | 44
Myoclonus 1 | 74
Nasal bridge wide 1 | 236
Neuraminidase 1 deficiency 1 | 1
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Nystagmus 1 | 317
Osteochondrodysplasias 1 | 72
Pasteurellosis 1 | 12
Pfaundler-Hurler Syndrome 1 | 12
Poor school performance 1 | 645
Progressive visual loss 1 | 36
Prominent lower lip 1 | 64
Proteinuria 1 | 144
Retinal Diseases 1 | 55
Rheumatoid arthritis 1 | 1,191
Seizures 1 | 596
Sensorineural Hearing Loss (disorder) 1 | 284
Short stature 1 | 531
Short thorax 1 | 21
Sialidosis type 1 1 | 1
Skeletal muscle atrophy 1 | 139
Skin Diseases, Vascular 1 | 5
Slurred speech 1 | 7
Speech Disorders 1 | 58
Splenomegaly 1 | 190
Stippled epiphyses 1 | 28
Tay-Sachs disease 1 | 6
Thickened facial skin with coarse facial features 1 | 108
Tremor 1 | 113
Type 1 diabetes mellitus 1 | 109
Vacuolated lymphocytes 1 | 8
Vascular abnormalities restricted to skin 1 | 4
Visual Impairment 1 | 174
Vitiligo 1 | 73
glioblastoma 1 | 5,792
inclusion-cell disease 1 | 16
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
medulloblastoma, large-cell 1 | 6,241
muscle degeneration 1 | 139
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
ulcerative colitis 1 | 1,819

Tissue

Female tissues 4 | 17,400
Skin and soft tissues 4 | 17,230
Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Urinary Tract 3 | 16,678
Respiratory system 2 | 16,393

Target Family

Enzyme 4 | 4,145

GO Function

exo-alpha-(2->8)-sialidase act... 4 | 4
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sialidase-3 NEU3 Tbio Enzyme -2.02704 118.2 35
Sialidase-1 NEU1 Tbio Enzyme -2.07548 116.0 278
Sialidase-4 NEU4 Tchem Enzyme -1.39624 25.1 115
Sialidase-2 NEU2 Tbio Enzyme -2.12721 129.5 166