Development Level

Tbio 30 | 11,445
Tchem 7 | 1,598
Tclin 4 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
enlarged heart 4 | 210
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
embryonic lethality prior to t... 3 | 278
increased startle reflex 3 | 112
abnormal bone mineralization 2 | 38
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased prepulse inhibition 2 | 82
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
increased lean body mass 2 | 172
increased monocyte cell number 2 | 63
abnormal bone structure 1 | 187
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal startle reflex 1 | 15
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased lymphocyte cell numb... 1 | 83
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
enlarged uterus 1 | 11
hydrometra 1 | 53
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
pale yolk sac 1 | 25
pallor 1 | 34
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Carcinoma 31 | 11,493
ovarian cancer 31 | 8,520
osteosarcoma 26 | 7,950
medulloblastoma, large-cell 22 | 6,241
atypical teratoid / rhabdoid tumor 18 | 5,112
lung cancer 18 | 4,740
glioblastoma 16 | 5,792
psoriasis 15 | 6,694
Cancer 14 | 2,499
Breast cancer 13 | 3,578
group 3 medulloblastoma 13 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
ependymoma 12 | 4,679
astrocytic glioma 11 | 2,597
malignant mesothelioma 11 | 3,232
primitive neuroectodermal tumor 11 | 3,035
group 4 medulloblastoma 10 | 1,855
non-small cell lung cancer 10 | 2,890
pituitary cancer 10 | 1,972
Breast Neoplasms 9 | 445
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Kidney cancer 8 | 2,613
Mammary Neoplasms 8 | 425
Obesity 8 | 678
diabetes mellitus 8 | 1,728
invasive ductal carcinoma 8 | 2,951
tuberculosis 8 | 2,010
Schizophrenia 7 | 1,160
adult high grade glioma 7 | 3,801
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638
ductal carcinoma in situ 7 | 1,745
lung adenocarcinoma 7 | 2,716
Rheumatoid arthritis 6 | 1,191
acute quadriplegic myopathy 6 | 1,158
interstitial cystitis 6 | 2,312
oligodendroglioma 6 | 2,850
ulcerative colitis 6 | 1,819
Colonic Neoplasms 5 | 142
Colorectal Neoplasms 5 | 243
Endometriosis 5 | 540
Nerve Degeneration 5 | 121
Neurodegenerative disease 5 | 414
Osteoporosis 5 | 363
Prostatic Neoplasms 5 | 495
adrenocortical carcinoma 5 | 1,428
cystic fibrosis 5 | 1,696
gastric carcinoma 5 | 807
non primary Sjogren syndrome sicca 5 | 891
pancreatic cancer 5 | 2,398
pediatric high grade glioma 5 | 1,064
Adenocarcinoma 4 | 122
Alzheimer's disease 4 | 658
Amyotrophic lateral sclerosis 4 | 451
Atherosclerosis 4 | 291
Bipolar Disorder 4 | 666
Carcinoma, Hepatocellular 4 | 228
Heart disease 4 | 306
Intellectual disability 4 | 1,016
Liver cancer 4 | 604
Liver carcinoma 4 | 240
Liver neoplasms 4 | 130
Melanoma 4 | 711
Multiple myeloma 4 | 1,332
Neoplasm Invasiveness 4 | 161
Neoplasm Metastasis 4 | 168
Pick disease 4 | 1,894
Vascular disease 4 | 319
colon cancer 4 | 1,478
hepatocellular carcinoma 4 | 547
juvenile dermatomyositis 4 | 1,187
Acquired metabolic disease 3 | 336
Adenoma 3 | 167
Alopecia 3 | 115
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Bladder Neoplasm 3 | 112
Depressive disorder 3 | 409
Endometrial cancer 3 | 311
Heart failure 3 | 162
Inflammatory bowel disease 3 | 151
Kidney disease 3 | 430
Liver Cirrhosis 3 | 181
Lung Neoplasms 3 | 232
Myocardial Infarction 3 | 151
Neurodegenerative Disorders 3 | 79
Osteoarthritis 3 | 184
Parkinson's disease 3 | 392
Stomach Neoplasms 3 | 300
Urinary Bladder Neoplasms 3 | 114
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
aldosterone-producing adenoma 3 | 665
dermatomyositis 3 | 966
lung carcinoma 3 | 2,843
progressive supranuclear palsy 3 | 676
sonic hedgehog group medulloblastoma 3 | 467
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Endocrine System 40 | 18,159
Female tissues 40 | 17,400
Male tissues 40 | 17,142
Nervous System 40 | 16,725
Skin and soft tissues 40 | 17,230
Blood and immune system 39 | 16,909
Digestive Tract 39 | 17,369
Liver and Pancreas 39 | 16,750
Respiratory system 39 | 16,393
Urinary Tract 39 | 16,678
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 21 | 12,091
Transcription Factor 7 | 1,400
Enzyme 6 | 4,145
Epigenetic 3 | 242
Kinase 2 | 634
Nuclear Receptor 2 | 48

GO Function

estrogen receptor binding 41 | 41
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
PAXIP1-associated glutamate-rich protein 1 PAGR1 Tbio Non-IDG -1.03602 8.61 59
CCR4-NOT transcription complex subunit 1 CNOT1 Tbio Non-IDG -2.10799 119.0 37
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
DDB1- and CUL4-associated factor 13 DCAF13 Tbio Non-IDG -0.63403 3.77 86
DDB1- and CUL4-associated factor 1 DCAF1 Tbio Non-IDG -1.71452 57.7 62
Nuclear receptor-interacting protein 1 NRIP1 Tbio Non-IDG -2.21323 183.8 155
Coiled-coil domain-containing protein 62 CCDC62 Tbio Non-IDG -0.91914 9.09 55
Insulin gene enhancer protein ISL-1 ISL1 Tbio Transcription Factor -2.63352 410.3 382
Transcription initiation factor TFIID subunit 10 TAF10 Tbio Non-IDG -1.26261 15.2 107