Development Level

Tbio 26 | 11,445
Tchem 4 | 1,598
Tclin 3 | 613

IMPC Phenotype

decreased vertical activity 2 | 208
preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased heart left ventricle... 1 | 28
decreased neutrophil cell numb... 1 | 42
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
impaired righting response 1 | 26
increased heart left ventricle... 1 | 4
increased hematocrit 1 | 46
increased mean corpuscular vol... 1 | 92
preweaning lethality, incomple... 1 | 499
thin ventricular wall 1 | 24

Disease

ovarian cancer 21 | 8,520
Carcinoma 20 | 11,493
Cancer 19 | 2,499
psoriasis 18 | 6,694
glioblastoma 14 | 5,792
lung adenocarcinoma 14 | 2,716
osteosarcoma 14 | 7,950
lung cancer 13 | 4,740
Breast cancer 12 | 3,578
medulloblastoma, large-cell 12 | 6,241
interstitial cystitis 11 | 2,312
pancreatic cancer 11 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
ulcerative colitis 10 | 1,819
Rheumatoid arthritis 9 | 1,191
atypical teratoid / rhabdoid tumor 9 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
invasive ductal carcinoma 9 | 2,951
lung carcinoma 9 | 2,843
malignant mesothelioma 9 | 3,232
diabetes mellitus 8 | 1,728
ependymoma 8 | 4,679
non-small cell lung cancer 8 | 2,890
spina bifida 8 | 1,074
breast carcinoma 7 | 1,638
colon cancer 7 | 1,478
pituitary cancer 7 | 1,972
astrocytoma 6 | 1,146
juvenile dermatomyositis 6 | 1,187
primary pancreatic ductal adenocarcinoma 6 | 1,109
Astrocytoma, Pilocytic 5 | 3,081
Down syndrome 5 | 499
Kidney cancer 5 | 2,613
Liver cancer 5 | 604
Prostatic Neoplasms 5 | 495
Schizophrenia 5 | 1,160
adult high grade glioma 5 | 3,801
cutaneous lupus erythematosus 5 | 1,057
gastric carcinoma 5 | 807
group 3 medulloblastoma 5 | 4,104
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
non primary Sjogren syndrome sicca 5 | 891
oligodendroglioma 5 | 2,850
pediatric high grade glioma 5 | 1,064
subependymal giant cell astrocytoma 5 | 2,287
Breast Neoplasms 4 | 445
Mammary Neoplasms 4 | 425
Multiple myeloma 4 | 1,332
Stomach Neoplasms 4 | 300
acute quadriplegic myopathy 4 | 1,158
chronic rhinosinusitis 4 | 512
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
hepatocellular carcinoma 4 | 547
inflammatory breast cancer 4 | 286
non-small cell lung carcinoma 4 | 317
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Amyotrophic lateral sclerosis 3 | 451
Arthritis, Juvenile 3 | 126
Atopic dermatitis 3 | 952
Carcinoma, Non-Small-Cell Lung 3 | 107
Carcinoma, Squamous Cell 3 | 110
Cleft Palate 3 | 271
Duchenne muscular dystrophy 3 | 601
Endometriosis 3 | 540
Erythropoietic protoporphyria 3 | 15
Juvenile arthritis 3 | 126
Liver Cirrhosis, Experimental 3 | 769
Melanoma 3 | 711
Multiple Sclerosis 3 | 540
Nerve Degeneration 3 | 121
Neurodegenerative disease 3 | 414
Protoporphyria, Erythropoietic 3 | 4
Pulmonary Fibrosis 3 | 106
Reperfusion Injury 3 | 86
Squamous cell carcinoma 3 | 129
aldosterone-producing adenoma 3 | 665
astrocytic glioma 3 | 2,597
gastric cancer 3 | 459
mucosa-associated lymphoid tissue lymphoma 3 | 484
nasopharyngeal carcinoma 3 | 1,058
pancreatic carcinoma 3 | 562
tuberculosis and treatment for 6 months 3 | 409
Depressive disorder 2 | 409
Kidney disease 2 | 430
Liver carcinoma 2 | 240
Type 2 diabetes mellitus 2 | 272
Vascular disease 2 | 319
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
fibroadenoma 2 | 559
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
progressive supranuclear palsy 2 | 676
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 33 | 16,909
Cardiovascular System 33 | 15,192
Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Respiratory system 33 | 16,393
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678
Nervous System 30 | 16,725

Target Family

Non-IDG 24 | 12,091
Enzyme 5 | 4,145
Kinase 4 | 634

GO Function

epidermal growth factor recept... 33 | 33
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Anterior gradient protein 2 homolog AGR2 Tbio Non-IDG -2.07496 136.6 594
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
Phospholipid scramblase 1 PLSCR1 Tbio Enzyme -1.81361 77.3 179
Suppressor of cytokine signaling 5 SOCS5 Tbio Non-IDG -2.04740 106.6 135
ADP-ribosylation factor 4 ARF4 Tbio Enzyme -1.67012 46.6 163
Receptor tyrosine-protein kinase erbB-4 ERBB4 Tclin Kinase -2.78704 558.2 1072
B-lymphocyte antigen CD20 MS4A1 Tclin Non-IDG -1.94302 79.5 2278
Protein FAM83B FAM83B Tbio Non-IDG -0.66208 4.45 48
Huntingtin-interacting protein 1 HIP1 Tbio Non-IDG -1.73638 55.9 202
CCR4-NOT transcription complex subunit 9 CNOT9 Tbio Non-IDG -0.98776 10.6 84