Development Level

Tbio 15 | 11,651
Tdark 3 | 6,593

IMPC Phenotype

abnormal behavior 1 | 298
corneal opacity 1 | 32
decreased eosinophil cell numb... 1 | 24
decreased heart rate 1 | 18
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979
prolonged PR interval 1 | 15
prolonged RR interval 1 | 8
thrombocytosis 1 | 27

Disease

Carcinoma 11 | 11,493
ovarian cancer 11 | 8,520
lung cancer 6 | 4,740
psoriasis 6 | 6,694
astrocytic glioma 5 | 2,597
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
atypical teratoid / rhabdoid tumor 4 | 5,112
dermatomyositis 4 | 966
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Autosomal recessive predisposition 3 | 1,442
Multiple myeloma 3 | 1,332
adult high grade glioma 3 | 3,801
colon cancer 3 | 1,478
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
Acquired scoliosis 2 | 281
Astrocytoma, Pilocytic 2 | 3,081
Byzanthine arch palate 2 | 194
Cancer 2 | 2,499
Cognitive delay 2 | 608
Curvature of spine 2 | 282
Global developmental delay 2 | 608
HIV Infections 2 | 102
Hypoplastic mandible condyle 2 | 275
Mandibular hypoplasia 2 | 275
Mental and motor retardation 2 | 608
Micrognathism 2 | 275
Optic Atrophy 2 | 242
Orbital separation diminished 2 | 23
Postnatal microcephaly 2 | 24
Short nose 2 | 132
Small nose 2 | 132
breast carcinoma 2 | 1,638
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
medulloblastoma 2 | 720
primitive neuroectodermal tumor 2 | 3,035
Agyria 1 | 15
Amyotrophic lateral sclerosis type 5 1 | 13
Axenfeld-Rieger syndrome 1 | 14
Blindness, Cortical 1 | 24
Charcot-Marie-Tooth disease 1 | 62
Congenital pectus carinatum 1 | 52
Convex nasal bridge 1 | 57
Cortical visual impairment 1 | 24
Decreased projection of maxilla 1 | 66
Decreased projection of midface 1 | 105
Deficiency of upper jaw bones 1 | 66
Delayed Puberty 1 | 97
Everted lower lip vermilion 1 | 54
Fatty liver disease 1 | 103
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Gait, Drop Foot 1 | 24
Generalized hirsutism 1 | 36
Global brain atrophy 1 | 7
Hyperkyphosis 1 | 111
Hyperlipidemia 1 | 43
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Hypoplasia of scrotum 1 | 24
Hypoplasia of the maxilla 1 | 66
Hypoplastic toes 1 | 29
Hypotrophic maxilla 1 | 66
Hypotrophic midface 1 | 105
Joint stiffness 1 | 84
Kyphosis deformity of spine 1 | 114
Liver Neoplasms, Experimental 1 | 59
Lordosis 1 | 54
Low posterior hairline 1 | 52
Maxillary retrognathia 1 | 66
Metatarsus Varus 1 | 24
Microphthalmia 1 | 76
Midface retrusion 1 | 105
Neuroleptic malignant syndrome 1 | 9
Postnatal growth retardation 1 | 57
Precociously senile appearance 1 | 18
Primitive reflexes (palmomental, snout, glabellar) 1 | 7
Progressive mental retardation 1 | 37
Prominent nasal bridge 1 | 57
Protruding lower lip 1 | 54
Pulmonary emphysema 1 | 48
Retrusion of upper jaw bones 1 | 66
Scurvy 1 | 10
Serum cholesterol raised 1 | 22
Shared Paranoid Disorder 1 | 5
Short hands 1 | 50
Small midface 1 | 105
Toeing-in 1 | 24
inflammatory breast cancer 1 | 286
non-small cell lung carcinoma 1 | 317
steroid-induced glaucoma 1 | 8

Tissue

Blood and immune system 18 | 16,909
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678
Cardiovascular System 17 | 15,192
Nervous System 17 | 16,725
Respiratory system 16 | 16,393

Target Family

Enzyme 12 | 4,145
Non-IDG 6 | 12,091

GO Function

enzyme regulator activity 18 | 18
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dolichol phosphate-mannose biosynthesis regulatory protein DPM2 Tdark Non-IDG -0.95378 9.57 34
Myotubularin-related protein 9 MTMR9 Tbio Non-IDG -0.73836 6.81 80
26S proteasome non-ATPase regulatory subunit 3 PSMD3 Tbio Enzyme -1.22269 15.9 168
V-type proton ATPase subunit H ATP6V1H Tbio Enzyme -1.26664 18.3 119
Apolipoprotein C-III APOC3 Tbio Non-IDG -2.93348 875.2 267
Glutamate--cysteine ligase regulatory subunit GCLM Tbio Enzyme -2.23855 156.3 277
Cytochrome c oxidase subunit 6A1, mitochondrial COX6A1 Tbio Enzyme -1.06552 12.3 194
Lys-63-specific deubiquitinase BRCC36 BRCC3 Tbio Enzyme -1.15215 13.4 225
Rab3 GTPase-activating protein non-catalytic subunit RAB3GAP2 Tbio Enzyme -0.61182 2.71 65
mRNA-decapping enzyme 1B DCP1B Tdark Non-IDG -0.31352 1.45 115