Development Level

Tbio 27 | 10,625
Tchem 13 | 1,890
Tdark 7 | 7,003
Tclin 1 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 3 | 633
abnormal eye morphology 2 | 38
anophthalmia 2 | 20
abnormal behavior 1 | 226
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal esophagus morphology 1 | 4
abnormal eye size 1 | 11
abnormal motor learning 1 | 4
abnormal pancreas morphology 1 | 6
abnormal pharyngeal arch morph... 1 | 2
abnormal placement of pupils 1 | 4
abnormal skin coloration 1 | 18
abnormal thyroid gland morphol... 1 | 3
abnormal trachea morphology 1 | 3
absent lymph nodes 1 | 3
athymia 1 | 1
corneal opacity 1 | 25
decreased body weight 1 | 174
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
enlarged spleen 1 | 26
hyperactivity 1 | 108
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased mean corpuscular hem... 1 | 93
narrow eye opening 1 | 15
thrombocytopenia 1 | 46

Disease

osteosarcoma 25 | 7,933
ovarian cancer 25 | 8,484
glioblastoma 16 | 5,572
psoriasis 16 | 6,685
medulloblastoma, large-cell 15 | 6,234
lung cancer 13 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
Cancer 10 | 2,346
atypical teratoid / rhabdoid tumor 10 | 4,369
invasive ductal carcinoma 8 | 2,950
lung carcinoma 8 | 2,844
malignant mesothelioma 8 | 3,162
Carcinoma 7 | 2,147
lung adenocarcinoma 7 | 2,713
oligodendroglioma 7 | 2,849
Pick disease 6 | 1,893
adrenocortical carcinoma 6 | 1,427
astrocytic glioma 6 | 2,241
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
non-small cell lung cancer 6 | 2,798
pilocytic astrocytoma 6 | 3,086
subependymal giant cell astrocytoma 6 | 2,287
acute myeloid leukemia 5 | 780
adult high grade glioma 5 | 2,148
astrocytoma 5 | 1,493
colon cancer 5 | 1,475
cutaneous lupus erythematosus 5 | 1,056
diabetes mellitus 5 | 1,663
ependymoma 5 | 2,514
group 3 medulloblastoma 5 | 2,254
interstitial cystitis 5 | 2,299
medulloblastoma 5 | 1,524
pancreatic cancer 5 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
tuberculosis 5 | 1,557
ulcerative colitis 5 | 2,087
Asthma 4 | 349
Vascular disease 4 | 281
active Crohn's disease 4 | 918
acute quadriplegic myopathy 4 | 1,157
group 4 medulloblastoma 4 | 1,875
non primary Sjogren syndrome sicca 4 | 840
pediatric high grade glioma 4 | 2,712
primary pancreatic ductal adenocarcinoma 4 | 1,271
primitive neuroectodermal tumor 4 | 3,031
progressive supranuclear palsy 4 | 674
Asymptomatic dengue 3 | 5
Atherosclerosis 3 | 275
Atopic dermatitis 3 | 944
Bipolar Disorder 3 | 266
Breast cancer 3 | 3,094
Multiple Sclerosis 3 | 498
Multiple myeloma 3 | 1,327
Obesity 3 | 616
breast carcinoma 3 | 1,614
cystic fibrosis 3 | 1,665
dermatomyositis 3 | 933
esophageal adenocarcinoma 3 | 737
inflammatory breast cancer 3 | 404
juvenile dermatomyositis 3 | 1,189
pituitary cancer 3 | 1,972
primary Sjogren syndrome 3 | 789
sonic hedgehog group medulloblastoma 3 | 1,482
Actinic keratosis 2 | 22
Alzheimer's disease 2 | 644
Amyotrophic Lateral Sclerosis 2 | 431
Barrett's esophagus 2 | 183
Chronic obstructive pulmonary disease 2 | 146
Coronary artery disease 2 | 240
Diabetes Mellitus, Experimental 2 | 106
Down syndrome 2 | 548
IGA Glomerulonephritis 2 | 454
Intellectual disability 2 | 573
Neurotoxicity Syndromes 2 | 26
Pancreatitis 2 | 97
Parkinson's disease 2 | 364
Parkinsonian Disorders 2 | 23
Peripheral Neuropathy 2 | 303
Pneumonia 2 | 133
Rheumatoid Arthritis 2 | 1,160
Schizophrenia 2 | 501
active ulcerative colitis 2 | 477
aldosterone-producing adenoma 2 | 664
atypical teratoid/rhabdoid tumor 2 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
chronic lymphosyte leukemia 2 | 232
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 557
gastric carcinoma 2 | 832
hepatocellular carcinoma 2 | 532
hereditary spastic paraplegia 2 | 313
interstitial lung disease 2 | 291
nasopharyngeal carcinoma 2 | 1,056
pancreatic carcinoma 2 | 567
posterior fossa group A ependymoma 2 | 1,511
sarcoidosis 2 | 358
spina bifida 2 | 1,064
tuberculosis and treatment for 6 months 2 | 686
Metachromatic Leukodystrophy, Adult-Type (disorder) 1 | 2

Tissue

Endocrine System 47 | 18,512
Digestive Tract 46 | 18,473
Female tissues 46 | 18,647
Liver and Pancreas 46 | 18,136
Urinary Tract 46 | 18,444
Male tissues 45 | 17,969
Nervous System 45 | 18,561
Blood and immune system 44 | 17,995
Skin and soft tissues 44 | 18,115
Cardiovascular System 43 | 17,958
Respiratory system 43 | 17,484

Target Family

Enzyme 22 | 4,146
Non-IDG 21 | 11,971
Kinase 4 | 634
Epigenetic 1 | 242

GO Function

enzyme activator activity 48 | 48
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Replication factor C subunit 1 RFC1 Tbio Non-IDG -1.40675 26.5 184
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OGT Tchem Enzyme -2.92944 916.6 217
mRNA-decapping enzyme 1B DCP1B Tdark Non-IDG -0.31186 1.45 90
CASP8 and FADD-like apoptosis regulator CFLAR Tchem Non-IDG -2.85930 837.3 538
Proactivator polypeptide-like 1 PSAPL1 Tdark Non-IDG 0.00000 64
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF N/A Tdark Non-IDG 0.00000 0
Leucine-rich colipase-like protein 1 LRCOL1 Tdark Enzyme 0.00000 0
Drebrin-like protein DBNL Tbio Non-IDG -1.15640 20.7 166
Apolipoprotein A-V APOA5 Tbio Non-IDG -2.54064 400.3 366
Matrix metalloproteinase-15 MMP15 Tchem Enzyme -1.67824 42.3 272