Development Level

Tbio 12 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal heart morphology 2 | 162
decreased lymphocyte cell numb... 2 | 83
enlarged heart 2 | 210
preweaning lethality, complete... 2 | 979
abnormal facial morphology 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
cleft palate 1 | 8
cyanosis 1 | 7
decreased prepulse inhibition 1 | 82
enlarged spleen 1 | 41
hydrometra 1 | 53
increased monocyte cell number 1 | 63
preweaning lethality, incomple... 1 | 499
scaly skin 1 | 4
small superior vagus ganglion 1 | 74

Disease

Carcinoma 13 | 11,493
ovarian cancer 12 | 8,520
osteosarcoma 10 | 7,950
psoriasis 9 | 6,694
Cancer 8 | 2,499
medulloblastoma, large-cell 8 | 6,241
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 7 | 5,792
lung cancer 7 | 4,740
malignant mesothelioma 7 | 3,232
ependymoma 6 | 4,679
Breast cancer 5 | 3,578
Craniofacial Abnormalities 5 | 151
ductal carcinoma in situ 5 | 1,745
pancreatic cancer 5 | 2,398
primitive neuroectodermal tumor 5 | 3,035
Congenital heart disease 4 | 93
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
diabetes mellitus 4 | 1,728
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
Acquired scoliosis 3 | 281
Astrocytoma, Pilocytic 3 | 3,081
Congenital Heart Defects 3 | 58
Congenital deafness 3 | 185
Curvature of spine 3 | 282
Deafness 3 | 198
Failure to gain weight 3 | 365
Hearing Loss, Partial 3 | 185
Hypoplastic mandible condyle 3 | 275
Kidney cancer 3 | 2,613
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Orbital separation excessive 3 | 244
Osteoarthritis 3 | 184
Pediatric failure to thrive 3 | 365
Pneumonia 3 | 174
active ulcerative colitis 3 | 764
cystic fibrosis 3 | 1,696
group 4 medulloblastoma 3 | 1,855
hearing impairment 3 | 199
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
medulloblastoma 3 | 720
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Abortion, Spontaneous 2 | 109
Alzheimer's disease 2 | 658
Autism spectrum disorder 2 | 101
Brachycephaly 2 | 88
Breast Neoplasms 2 | 445
Broad cranium shape 2 | 88
Broad forehead 2 | 59
Chemical and Drug Induced Liver Injury 2 | 195
Chronic otitis media 2 | 52
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Down syndrome 2 | 499
Exophthalmos 2 | 112
Frontal bossing 2 | 157
Hypertension 2 | 396
Kidney disease 2 | 430
Liver Cirrhosis 2 | 181
Liver disease 2 | 237
Male infertility 2 | 206
Melanoma 2 | 711
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Nonsyndromic deafness 2 | 142
Pick disease 2 | 1,894
Precursor Cell Lymphoblastic Leukemia-Lymphoma 2 | 49
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Right atrial isomerism 2 | 29
Spontaneous abortion 2 | 113
Stomach Neoplasms 2 | 300
Strabismus 2 | 270
Vascular disease 2 | 319
Waldenstrons macroglobulinemia 2 | 765
Wide skull shape 2 | 88
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
ear infection chronic 2 | 52
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
lung carcinoma 2 | 2,843
urothelial carcinoma 2 | 318

Tissue

Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Skin and soft tissues 15 | 17,230
Female tissues 14 | 17,400
Respiratory system 14 | 16,393
Urinary Tract 14 | 16,678
Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Liver and Pancreas 13 | 16,750

Target Family

Transcription Factor 11 | 1,400
Enzyme 2 | 4,145
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GO Function

enhancer binding 15 | 15
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Steroid hormone receptor ERR2 ESRRB Tchem Nuclear Receptor -1.95523 86.9 173
Mesoderm posterior protein 1 MESP1 Tbio Transcription Factor -1.38536 26.8 208
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657
Transcription factor E2-alpha TCF3 Tbio Transcription Factor -2.80290 601.6 434
Aryl hydrocarbon receptor AHR Tchem Transcription Factor 0.00000 773
Transcription factor 12 TCF12 Tbio Transcription Factor -2.24606 159.8 253
Retinoic acid-induced protein 1 RAI1 Tbio Epigenetic -1.75290 58.1 53
Aryl hydrocarbon receptor nuclear translocator ARNT Tbio Transcription Factor -2.53687 261.2 474
Mothers against decapentaplegic homolog 3 SMAD3 Tbio Transcription Factor -3.19667 1403.6 1526